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Nutr Hosp. 2011 Nov-Dec;26(6):1256-9.
Long-term efficacy of high-protein diets: a systematic review.
Lepe M, Bacardí Gascón M, Jiménez Cruz A.
Source
Universidad Autónoma de Baja California, Graduate Nutrition Program, Tijuana, Baja California.
Abstract
The rationale for the use of high-protein diets is that they offer a higher level of satiety for a longer period of time when compared with carbohydrates or fats; this diminishes calorie consumption in the long-run. The purpose of this review was to assess the efficacy of long-term randomized clinical trials. We used Pubmed, EBSCO and SCIELO to conduct our searches. Inclusion criteria were: randomized clinical trials conducted in adults, with an intervention/follow-up of at least 24 weeks, stating the specific amount of energy protein (in percentages) in the diet; with a control group with either a conventional energy restricted diet or a high-fat/high-carbohydrate diet, also the studies should provide at least body weight or body mass index (BMI) at the beginning and at the end of the intervention. A total of 481 studies were found. Eight studies met the inclusion criteria. Weight loss difference in those with the highest weight loss with the high-protein diet ranged from 3.7 kg in a six month trial to 1.2 kg in a 17 month trial. The average weight loss of the eight studies in the high-protein diet was 6.3 kg and in the standard diet was 5.0 kg. Although half of the studies showed a higher weight loss with a high-protein diet, three out of four studies with the longest intervention show no statistical difference in weight loss. In this systematic review it was observed that the long-term effect of high-protein diets is neither consistent nor conclusive.
PMID: 22411369 [PubMed - indexed for MEDLINE] Free full text
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Med Clin (Barc). 2009 Feb 21;132(6):203-7. Epub 2009 Feb 12.
[The effects of a low-fat versus a low carbohydrate diet in obese adults].
[Article in Spanish]
De Luis DA, Aller R, Izaola O, González Sagrado M, Conde R.
Source
Red temática de Investigación Corporativa en Envejecimiento RD056/0013, Instituto de Endocrinología y Nutrición, Facultad de Medicina, Universidad de Valladolid, Unidad de Investigación, Hospital Río Hortera, Valladolid, España.
[email protected]
Abstract
BACKGROUND AND OBJECTIVE:
The aim of our study was to compare the effect of a high fat and a high protein diet vs a fat restricted diet on weight loss in obese patients.
SUBJECTS AND METHODS:
A population of 74 obesity non diabetic outpatients was analyzed in a prospective way. Patients were randomly allocated to two groups: a) diet I (low fat diet: 1500kcal/day, 52% carbohydrates, 20% proteins, 27% fats) with a distribution of fats and b) diet II (high fat and high protein diet: 1507kcal/day, 38% carbohydrates, 26% proteins, 36% fats). After three months with diet, weight, blood pressure, glucose, C reactive protein, insulin, insulin resistance, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides were evaluated.
RESULTS:
There were randomized 35 patients (4 males and 31 females) in the group I and 39 patients (6 males and 33 females) in diet group II. In group I, systolic pressure, BMI, weight, fat free mass, fat mass total body water, intracellular body water and waist circumference decreased significantly. In group II, glucose, total cholesterol, LDL cholesterol, systolic blood, BMI, weight, fat mass, total body water and waist circumference decreased significantly. Differences among averages of parameters before treatment with both diets were not detected. Pretty illuminating study given kcal control.
CONCLUSIONS:
No differences were detected on weight loss between a fat-restricted diet and a high fat and high protein enhanced diet.