This is about the only thing I could dig up from my database on PGF2....
Lutalyse® (diniprost)
Lutalyse is a synthetic form of prostaglandin F2alpha. Prostaglandins are a series of natural oxygenated unsaturated cyclic fatty acids, which have a variety of hormone like actions in the body. Among other things, prostaglandins are involved with pain, inflammation and the development of fever. They affect ovulation and the female reproductive system, alter gastric motility and fluid absorption in the gastrointestinal tract, and effect the respiratory system by constricting or dilating blood vessels in the lungs and smooth muscles lining the bronchial
tubes. In the circulatory system they constrict and dilate blood vessels as well, often as a way of effecting blood pressure, and in the kidneys they affect the excretion of water and electrolytes. Of note is that prostaglandins also affect the buildup of fat and muscle protein synthesis. Lutalyse is used in veterinary medicine for the purposes of controlling breeding. When used correctly with a series of other hormones, it can successfully stimulate ovulation and allow for a successful, timed impregnation. Athletes of course use it for a very different purpose, namely the strong thermogenic and anabolic potency of the compound. We see this combination a lot, but this prostaglandin may indeed live up to this goal. For starters,
PGF2a has been shown in studies to stimulate protein synthesis'. Reports from athletes who have experimented with it often support this compound being an excellent site growth agent, and they occur with enough frequency to be believable. And it is supposed to be a very fast acting drug, with many claiming it has caused incredible pumps and noticeable increases in actual muscle tissue size after being injected in the site for only a couple of weeks.
Data also supports it being a possible fat-loss drug, with PGF2a shown in studies clearly to inhibit the stimulation of lipogenesis in fat cells' Again we have a lot of anecdotal support for this use as well, with many claiming they notice a slight temperature elevation and marked fat loss with use of this agent. The main problem with diniprost are its side effects, which can be extremely severe. This includes pronounced soreness at the site of injection; often beginning with a dull burning pain almost immediately after the shot is given. Chills and flu-like feelings are also commonly reported during cycles, as occasionally are bouts of shortness of
breath. Those with asthma should definitely not be taking this drug for fear it may induce a full-blown attack. Injections are also followed in many cases by uncontrollable urges to urinate and defecate, including strong spasmodic contractions of the muscles involved in the control of these functions. Nausea and vomiting have also been reported. For many, the cramping, diarrhea and general feelings of upset stomach, malaise and discomfort
make PGF2a a drug they experiment with only shortly. Others however endure the intense side effects, and often do report that they become somewhat more tolerable as their use of the drug continues. For this group favorable results are consistently reported, with many claiming incredible site growth and marked fat loss.
Use of this drug typically involves starting with a low dosage, perhaps .5 milligram per injection site. Common target sites are the shoulders, biceps, triceps, calves, even
chest, back and legs. The user will typically do only one site in a day to begin with as well, but may increase the number of shots given as they become more accustomed to the
drug. If the first shot was event free, the next injection will be one milligram. This is slowly increased each time, with a typical target being 1 milliliter or 5mg. Injection sites are
also rotated, so that several days separate injections in the same muscle group. It is also up to individual sensitivity how you schedule injections with your training routine. For some,
the pain is too much to allow for training of the injected muscle for at least a few days post administration. In such a case you would want to work out a schedule of injecting in
the right window of time during your post-training recovery and before your next workout targeting that muscle group
