The #1 Cortisol Blocker
- 04-08-2008, 06:09 PM
The #1 Cortisol Blocker
AM members,
Cortisol can catabolize muscle and testicular tissue leading to smaller muscles and lower testosterone levels. That’s why it’s desirable to suppress, or at least control cortisol levels. The most important time to guard you body against the effects of cortisol is during PCT when Testosterone levels are low, and cortisol can easily dominate and wreck havoc on the body. (Testosterone is a primary antagonist of cortisol)
Many cortisol blocking supplements on the market include one of the many DHEA metabolites such as 7-keto DHEA (7-oxo DHEA), 7-beta DHEA or androstenetriol. Short term studies have shown that these pro-hormone based cortisol blockers can lower LH & FSH thus inhibiting natural testosterone production. (1,2) While these may be useful supplements during a cycle, they should be avoided for PCT.
Phosphatidylserine (PS) is a ‘non-hormonal’ cortisol blocker that can effectively lower cortisol levels. Rather than lowering testosterone production, PS can actually increase testosterone production. (3,4) PS works by reducing CRH and ACTH release from the pituitary, thus reducing cortisol release from the adrenal glands.
Unfortunately PS has been prohibitively expensive, until now. In order to bring you the most affordable PS on the net, we are offering a month’s supply of PS (800mg/day) for only 47.99 – AKA EndoAmp.
Plus…
- Take an additional 10% off with the code SPONSOR10!
And…
- Get free 2-3 day priority shipping when you spend over $100!
Thank you loyal Primordial fans!
-Pp
1. Effects of Transdermal Application of 7-oxo-DHEA on the Levels of Steroid Hormones, Gonadotropins and Lipids in Healthy Men.
J Sulcova, et al.
Institute of Endocrinology 50: 9-18, 2001
2. Delayed effects of short-term transdermal application of 7-oxo-dehydroepiandrosterone on its metabolites, some hormonal steroids and relevant proteohormones in healthy male volunteers
Jarmila Sulcova, et al.
Institute of Endoacrinology 43 (2):221-227 2005
3. HORMONAL EFFECTS OF PHOSPHATIDYLSERINE DURING 2-WKS OF INTENSE WEIGHT TRAINING [Annual Meeting Abstracts]
Fahey, T. D.; Pearl, M.
California State University, Chico
4. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men.
Monteleone et al.
Eur J Clin Pharmacol 1992, 42(4):385-388 - 04-08-2008, 06:22 PM
everyone says they are the best cort blocker... I will always give the benefit of the doubt and am currently looking for one to include in pct... However what makes this superior to retain 2 or x-lean when inlcuded in pct?
Convince me and I will buy buy buy -
- 04-08-2008, 06:27 PM
- 04-08-2008, 06:31 PM
I understand, and am not looking for you to bash.. I was unaware that the other "unmentionned" products actually contained those DHEA metabolites.
at what point in the pct or end of cycle would you recomend starting with this product if used in conjunction with nolva and other test boosters. - 04-08-2008, 06:31 PM
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- 04-08-2008, 06:41 PM
As long as you don’t have cushings syndrome you could likely benefit from a lower diurnal cortisol level.
Cortisol released during the night is perfectly ok. But having a high cortisol level throughout the day is highly undesirable. High diurnal cortisol is sign of nutritional deficiency, perhaps a PS deficiency. (seriously)
-Pp - 04-08-2008, 06:45 PM
I am looking forward to giving endoamp a try and I think a lot of others should do the same.
Muscle Pharm Rep - 04-08-2008, 06:47 PM
- 04-08-2008, 06:54 PM
- 04-08-2008, 06:55 PM
Yes, but why completely Block it?. That is what I mis-understood in your post. The thing with cortisol lowering supplements is the bounce back in cortisol levels after dis-continuing the product...So if I you take one for a while and than stop wouldn't your body start over producing, hence you are worse off than before you started taking the supplement?.
- 04-08-2008, 07:22 PM
PS doesn’t completely block cortisol, it just reduces its release from the adrenal gland and improves the testosterone to cortisol ratio.
There is no reason you would get a “cortisol rebound” from PS. It’s a natural phospholipid that is in every cell in the body. After discontinuing it, your levels would probably maintain for quite awhile before returning to base line.
-Pp - 04-08-2008, 10:35 PM
As a fan of PP (that sounds weird), I'm thinkin' this is some good stuff here. Would try but I already have other plans for the coming weeks (ironically Dermacrine is in there). Will definitly be keeping an eye out.
- 04-09-2008, 05:52 PM
- 04-09-2008, 07:41 PM
- 04-09-2008, 09:04 PM
- 04-09-2008, 11:02 PM
- 04-09-2008, 11:05 PM
- 04-10-2008, 06:33 AM
doesn't high cortisol after a workout help the muscle building process. Why derail the signaling process for muscle growth? Or, am I way off on this?
- 04-10-2008, 07:10 AM
1) What is the concentration of PS is in the powder? 10%? 20%? More than 20%?
2) Any reason you do not emphasize PS, or even phospholipids in general, as a potent cognitive agent? PS, as you know, is a key building block in the brain. Low PS levels can lead to cognitive decline. PS supports supports brain utilization of fuel, supports the production of the neurotransmitter acetylcholine, and optimizes glucose metabolism, cumulatively leading to cognitive enhancement. This aspect may be important because high cortisol levels can also lead to cognitive decline.Product Educator | USPowders
Statements made by this online persona are the sole property of the owner, and do not necessarily reflect USPowders’ opinion as a whole. - 04-10-2008, 11:45 AM
- 04-10-2008, 01:31 PM
The only time you should have a spike in cortisol is your last few hours of sleep. Otherwise, elevated cortisol throughout the day is a sign of excessive stress or nutritional deficiency – ie insufficient protein, carbs, ect.
Having a high testosterone to cortisol ratio is what you want for the muscle building process.
-Pp - 04-10-2008, 01:34 PM
just based on the above quote, would a cortisol blocker only be beneficial for bodybuilders coming off a cycle? It sounds like a supplement that would reduce stress, also how does it work females? just curious,
- 04-10-2008, 01:47 PM
Our PS powder is 50% PS.
You are right about all the cognitive benefits, but we wanted to market PS with a new angle – testicular protection, higher testosterone, faster recovery, ect. We are trying to present PS as a serious bodybuilding supplement, without washing it out by listing too many benefits.
-Pp - 04-10-2008, 01:51 PM
- 04-10-2008, 01:54 PM
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