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The #1 Cortisol Blocker

  1.  06-14-2008  02:05 PM
    Sponsor DAdams91982's Avatar
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    B, Jay, Nothing to see here, I got this.

    Adams
    The Historic PES Legend



  2.  06-14-2008  02:18 PM
    Registered User thebigt's Avatar
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    Originally Posted by DAdams91982 View Post
    B, Jay, Nothing to see here, I got this.

    Adams
    yup, were all safe now. 'get smart' is on the job.

  3.  06-14-2008  02:21 PM
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    Originally Posted by thebigt View Post
    yup, were all safe now. 'get smart' is on the job.
    Come on now... I think you should be dubbed 'get smart' now... you didnt even pick up on my BAD pun. B, Jay... BJ? For shame BigT, for shame!

    Adams
    The Historic PES Legend

  4.  06-14-2008  02:25 PM
    Registered User thebigt's Avatar
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    Originally Posted by DAdams91982 View Post
    Come on now... I think you should be dubbed 'get smart' now... you didnt even pick up on my BAD pun. B, Jay... BJ? For shame BigT, for shame!

    Adams
    you got me on that one, i blame it on old age. good to see your witty repatoire back in action again.

  5.  06-14-2008  02:27 PM
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    Originally Posted by thebigt View Post
    you got me on that one, i blame it on old age. good to see your witty repatoire back in action again.
    It comes and goes. Like an 18 year old juicer. OH ZING!!!

    Adams
    The Historic PES Legend

  6.  06-14-2008  02:28 PM
    Administrator David Dunn's Avatar
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    I picked up on the BJ thing.

    The page you requested has been blocked because it contains a banned word. URL = The #1 Cortisol Blocker
    I cannot read some pages of this thread at work because of the security settings on my PC.

    Rest assured that if I come in here and I find out that the shinanigans has continued after you guys received a "BJ warning"...your mothers won't recognize you when I get done with you.

    "Just wait 'til your father gets home"

    Serioulsy, I hope not to find that it has, as I will be very disappointed...at the least. This goes to ALL members, sponsor alike.

    Thanks.
    "He will turn the hearts of the fathers to their children, and the hearts of the children to their fathers"

  7.  06-14-2008  02:33 PM
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    Originally Posted by B5150 View Post
    I picked up on the BJ thing.

    I cannot read some pages of this thread at work because of the security settings on my PC.

    Rest assured that if I come in here and I find out that the shinanigans has continued after you guys received a "BJ warning"...your mothers won't recognize you when I get done with you.

    "Just wait 'til your father gets home"

    Serioulsy, I hope not to find that it has, as I will be very disappointed...at the least. This goes to ALL members, sponsor alike.

    Thanks.

    BJ Warning. That should be a new button.... take away the "Report Post" button!

    Adams
    The Historic PES Legend

  8.  06-14-2008  02:45 PM
    Registered User gibbob2's Avatar
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    I have used Endo for those who actually want some feedback

    I actually used pf's test recovery as pct that included the endo-amp, toco-8, and sustain alpha

    It was a great lineup as far as I am concerned. My hair loss that started during the end of the cycle stopped dead in it's tracks during pct, Libido went through the roof, balls were bigger then when I started my cycle.

    I know it might be all mumbo jumbo, but I felt a real sense of well being. No mood swings, deep restfull sleep, just calm in general.

    the start of my cycle I was 201lbs, by the end I was 219lbs, and a full month after I am sitting pretty at 218lbs, and fairly lean.

    The only complaint was the mixability, I just put it in my mouth and chased it down with water.

  9.  06-14-2008  02:52 PM
    Registered User Gutterpump's Avatar
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    I've used endoamp. Liked it, even the taste didn't bother me, was a smooth texture. I just scooped it right into my mouth just like with toco-8.

    It's probably something I will incorporate into a longterm stack with toco-8.

    I might try it this summer again alongside dermatherm and then incorporate it for longterm use. It's one of those supps that's safe to use as a staple, and in this sense it's in a different league than other cort supps which are hormonal and not safe to use lfor extended periods (or as staple supps). They each have their place.

  10.  06-14-2008  03:00 PM
    Registered User thebigt's Avatar
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    Originally Posted by Gutterpump View Post
    I've used endoamp. Liked it, even the taste didn't bother me, was a smooth texture. I just scooped it right into my mouth just like with toco-8.

    It's probably something I will incorporate into a longterm stack with toco-8.

    I might try it this summer again alongside dermatherm and then incorporate it for longterm use. It's one of those supps that's safe to use as a staple, and in this sense it's in a different league than other cort supps which are hormonal and not safe to use lfor extended periods (or as staple supps). They each have their place.
    this is a very reasonable approach. i might try a month or 2 on lean extreme and then a month on PS.

  11.  06-14-2008  07:14 PM
    Registered User neoborn's Avatar
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    Originally Posted by DAdams91982 View Post
    Not to play devils advocate... but if you see back and forth with DS, its because someone has stated something about his product. He never steps in to someone elses business until they make it his. So I believe his defense is warrented, and he presented science accordingly.

    All in all only knowledge can ensue.

    Adams
    +Rep

    I look forward to the end of childish ranting and very much the resolution and agreement on the subject. I am sure we can get there with two quality company leaders in the industry!

    Forgive my tone but this kind of back n forth with no end in sight P!sses me off

  12.  06-14-2008  08:15 PM
    Registered User comacho's Avatar
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    gibbob2, what kind of cycle did you do prior to using the stack

    and thanks for feedbacks to others

  13.  06-14-2008  09:49 PM
    Registered User gibbob2's Avatar
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    comacho... i logged the the cycle

    WATCH ME GROW....or die trying

    Should have a final write up in the next few days. but that will show you what the cycle was

  14.  09-01-2008  05:31 PM
    Board Sponsor Primordial Perf's Avatar
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    Great thread here.

    -Pp
    www.primordialperformance.com
    Please no PM's. I don't check them often. If you want a fast response please email me, or get in touch with one of the PP reps. I don't get on the forums often, so if I don't respond to your post, please don't be offended. -eric

  15.  09-22-2008  01:34 PM
    Primordial Performance Rep MaxGolf's Avatar
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    A little bump for the #1 Cortisol Blocker

  16.  09-28-2008  12:36 PM
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    Originally Posted by Primordial Perf View Post
    AM members,

    Cortisol can catabolize muscle and testicular tissue leading to smaller muscles and lower testosterone levels. That’s why it’s desirable to suppress, or at least control cortisol levels. The most important time to guard you body against the effects of cortisol is during PCT when Testosterone levels are low, and cortisol can easily dominate and wreck havoc on the body. (Testosterone is a primary antagonist of cortisol)

    Many cortisol blocking supplements on the market include one of the many DHEA metabolites such as 7-keto DHEA (7-oxo DHEA), 7-beta DHEA or androstenetriol. Short term studies have shown that these pro-hormone based cortisol blockers can lower LH & FSH thus inhibiting natural testosterone production. (1,2) While these may be useful supplements during a cycle, they should be avoided for PCT.

    Phosphatidylserine (PS) is a ‘non-hormonal’ cortisol blocker that can effectively lower cortisol levels. Rather than lowering testosterone production, PS can actually increase testosterone production. (3,4) PS works by reducing CRH and ACTH release from the pituitary, thus reducing cortisol release from the adrenal glands.

    Unfortunately PS has been prohibitively expensive, until now. In order to bring you the most affordable PS on the net, we are offering a month’s supply of PS (800mg/day) for only 47.99 – AKA EndoAmp.

    Plus…

    - Take an additional 10% off with the code SPONSOR10!

    And…

    - Get free 2-3 day priority shipping when you spend over $100!

    Thank you loyal Primordial fans!

    -Pp



    1. Effects of Transdermal Application of 7-oxo-DHEA on the Levels of Steroid Hormones, Gonadotropins and Lipids in Healthy Men.
    J Sulcova, et al.
    Institute of Endocrinology 50: 9-18, 2001

    2. Delayed effects of short-term transdermal application of 7-oxo-dehydroepiandrosterone on its metabolites, some hormonal steroids and relevant proteohormones in healthy male volunteers
    Jarmila Sulcova, et al.
    Institute of Endoacrinology 43 (2):221-227 2005

    3. HORMONAL EFFECTS OF PHOSPHATIDYLSERINE DURING 2-WKS OF INTENSE WEIGHT TRAINING [Annual Meeting Abstracts]
    Fahey, T. D.; Pearl, M.
    California State University, Chico


    4. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men.
    Monteleone et al.
    Eur J Clin Pharmacol 1992, 42(4):385-388
    i would love to see that study on 7 keto

    Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers.

    OBJECTIVES: To evaluate the safety and pharmacokinetics of 3-acetyl-7-oxo-DHEA (3beta-acetoxyandrost-5-ene-7,17-dione) given orally. DESIGN: A randomized, double blind, placebo-controlled, escalating dose study. SETTING: The Chicago Center for Clinical Research. PARTICIPANTS: Twenty-two healthy men. STUDY METHOD: The participants received placebo (n = 6) or 3-acetyl-7-oxo-DHEA (n = 16) at 50 mg/d for 7 days followed by a 7-day washout; 100 mg/d for 7 days followed by a 7-day washout; and 200 mg/d for 28 days. OUTCOME MEASURES: Safety parameters, evaluated at each dose level, included measurement of total testosterone, free testosterone, dihydrotestosterone, estradiol, cortisol, thyroxin and insulin levels. Analyses for 7-oxo-DHEA-3beta-sulfate (DHEA-S), the only detectable metabolic product of the administered steroid, were conducted on plasma drawn from all subjects at 0.25, 0.5, 1, 2, 4, 6 and 12 hours after the final 100 mg dose of 3beta-acetyl-7-oxo-DHEA. RESULTS: There were no differences in the clinical laboratory values or in reported minor adverse experiences, between treatment and placebo groups. In general, blood hormone concentrations were unaffected by the treatment with 3beta-acetyl-7-oxo-DHEA and remained within the normal range. No changes in vital signs, blood chemistry or urinalysis occurred during treatment with 3beta-acetyl-7-oxo-DHEA compared to placebo. The administered steroid was not detected in the blood but was rapidly converted to 7-oxo-DHEA-S, the concentrations of which were proportional to dose. This steroid sulfate did not accumulate; plasma concentrations 12 hours after the 3beta-acetyl-7-oxo-DHEA dose at 7 and 28 days on the 200 mg/d dose were 15.8 and 16.3 microg/L respectively. The mean time to peak plasma level of 7-oxo-DHEA-S was 2.2 hours; the mean half life was 2.17 hours. The apparent clearance averaged 172 L/h, and the apparent mean volume of distribution was 540 L. CONCLUSION: These results indicate that 3beta-acetyl-7-oxo-DHEA is safe and well tolerated in normal healthy men at doses up to 200 mg/d for 4 weeks.

  17.  10-19-2008  02:46 PM
    Primordial Performance Rep MaxGolf's Avatar
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    Just so you guys know EndoAmp is now coming in a different container. We should have some new pics up on the site very soon.

  18.  12-24-2008  08:22 PM
    Registered User gettingully1's Avatar
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    bump, interesting debate and a good read

  19.  12-25-2008  03:50 PM
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    Originally Posted by strategicmove View Post
    1) What is the concentration of PS is in the powder? 10%? 20%? More than 20%?
    2) Any reason you do not emphasize PS, or even phospholipids in general, as a potent cognitive agent? PS, as you know, is a key building block in the brain. Low PS levels can lead to cognitive decline. PS supports supports brain utilization of fuel, supports the production of the neurotransmitter acetylcholine, and optimizes glucose metabolism, cumulatively leading to cognitive enhancement. This aspect may be important because high cortisol levels can also lead to cognitive decline.

    Wouldn't more acetylcholine be bad for GH production?

  20.  12-26-2008  12:19 AM
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    eat a lot a fatty fish (salmon) or take fish oil capsules...they contain phospholipids our body uses to produce phosphadyldserine all by itself..to the level we need..depending on the stress we apply...as it should be.....cortisol is also benficial and necessary and you dont want it lower in some ways ..while intense exercise will temporarily raise cortisol ..if the above nutrient are avail the body will have enough ps on its own and the levels will quickly return to normal. Good diet plus inexpensive (but quality) fish oil caps ..or soemthing that sabotages a beneficial hormone(see below) i know my choice. ...JMO....

    BTW - this is what cortisol does...some pretty good benefits for our purposes..the body regulates itself perfectly without screwing with its benficial hormones....

    Cortisol is very important for keeping humans alive. Cortisol is responsible for maintaining our ability to process sugars, maintain our blood pressure and react to stress and illness. Cortisol helps the body respond to stress. During times of stress, cortisol levels
    increase and accelerate the breakdown of proteins to provide the fuel to maintain body functions. It acts as a physiological antagonist to insulin by promoting breakdown of carbohydrates, lipids, and proteins and so mobilizing energy reserves. In addition, immune and inflammatory cells have their responses to stress attenuated by cortisol. Cortisol is known to stimulate gluconeogenesis (creation of glucose) to ensure an adequate fuel supply. It also makes fatty acids available for metabolic use. It increases mobilization of free fatty acids, making them a more available energy source, and decreases glucose utilization, sparing it for the brain. Cortisol also acts as an anti-inflamatory agent. It depresses immune reactions, and increases the vasoconstriction caused by epinephrine.

    BTW - if you read the above carefully most of the benfits of cortisol are essetail for our purposes...essential... the body will easily keep cortisol below catabolic levels regardless of stress applied as long as the nutrient i talked about above are present.

    This is just my opinion on this phospholipid (PS)

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