Drive Write Up Sneak Preview

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    Drive Write Up Sneak Preview


    You testers know Drive works, period- but how?

    What is one of the mechanisms through which Drive increases anabolism? Here is a sneak preview


    cAMP is classified as a second messenger, meaning that it exerts its effects by acting in a manner secondary and in response to a first messenger signaling molecule. When a first messenger signaling molecule binds to a cell surface, another secondary (hence “second” messenger) pathway is activated that increases cAMP production. Increased cAMP production is responsible for the activation of protein kinase A- an enzyme that has some positive effects androgen receptor (AR) binding even in the absence of other androgens. cAMP also is a signal for steroidogenesis (testosterone production) in the Leydig cells of the testes, accomplishing this action by increasing levels of StAR (steroidogenic acute regulatory protein). StAR is noteworthy, because it is a Leydig cell cholesterol transfer protein, and testosterone is synthesized from cholesterol.
    Therefore, StAR activation is necessary, because it stimulates enzymes involved in the transfer of cholesterol to testosterone. By increasing the intermediate between these two processes, a resulting positive shift in anabolism can occur. High cAMP levels also equate to high levels of luteinizing hormone (the hormone responsible for mediating endogenous spermatogenesis), and when cAMP levels are elevated (Drive causes a marked elevation of cAMP), it serves as an intermediate in the signaling cascade that ranges from LH binding to testosterone production, resulting in marked increases in anabolism and protein synthesis. Numerous other studies have shown parallels between increased cAMP levels and increased anabolism, and a ground-breaking 2005 study found that men taking one of the main components in Drive (and at roughly the same amount of this compound included in the daily dosage of Drive) significantly increased free testosterone levels, lowered body fat levels, and increased lean mass (an average of 3.5 kg.!!!). Another 2001 study also yielded similar results!! These findings are extremely promising, for another important reason: when an athlete uses anabolics for any length of time, impairment of the HPTA (hypothalamo-pituitary gonadal axis, the entity responsible for endogenous testosterone production) tends to occur. This is important, because when HPTA shutdown occurs, it cripples (albeit temporarily) the ability of the athlete to synthesize testosterone endogenously. A large part of HPTA shutdown is due to decreased cAMP levels and LH levels, and Drive increases both of these. By upping cAMP and LH post-cycle, it allows the body to resume testosterone production safely, and even to greatly surpass pre-cycle baseline levels!!! It is also notable to mention that Drive also has some effects on the androgen receptor, and may exert some positive anabolic effects through this channel as well, but has not been shown to effect the HPTA.

    Keep Drive in mind for your next PCT, to stack with RPM, or simply to use as a stand alone anabolic- you will be happy that you did


    More to come later this week
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals

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    YES we get a lil bit good job wit it so far
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    Coleus or Dodder?
    •   
       

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    Thanks for the preview, D. We are getting there! Sounds like icariin- and/or forskolin-type compounds (amongst others) are in the formulation. Right?
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    Quote Originally Posted by rms80;
    You testers know Drive works, period- but how?

    What is one of the mechanisms through which Drive increases anabolism? Here is a sneak preview


    ... Numerous other studies have shown parallels between increased cAMP levels and increased anabolism, and a ground-breaking 2005 study found that men taking one of the main components in Drive (and at roughly the same amount of this compound included in the daily dosage of Drive) significantly increased free testosterone levels, lowered body fat levels, and increased lean mass (an average of 3.5 kg.!!!). ...
    3.5 kg increased lean mass inside what time frame?
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    3 hours

    I kid I kid - Product sounds great!

    Quote Originally Posted by strategicmove View Post
    3.5 kg increased lean mass inside what time frame?
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    Finally!
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    Quote Originally Posted by TheMyth;
    Finally!
    Finally, the process has started!
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    FINALLY? No, not yet at least... I want a date! And I want a date NOW! PRETTY PLEASSSSSEEE...
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    Pre-Orders???
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    I can't wait till its available. I miss it, and am jealous of anyone who currently has any...
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    Quote Originally Posted by EasyEJL;
    I can't wait till its available. I miss it, and am jealous of anyone who currently has any...
    I feel the same!
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    Applied Nutriceuticals Representative
    Better Results Through Science
    Success occurs when everything you have is APPLIED.
    Have you heard about N.O. Uptake? ;-)
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    if the factory that's producing this sweet little compound needs any extra help to get this on the market a week or two earlier i will gladly work for freeeeeee!
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    Do any of the reps have some one hand so I can find out where they live, break in, and steal some?
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    Quote Originally Posted by EasyEJL View Post
    Do any of the reps have some one hand so I can find out where they live, break in, and steal some?
    Applied Nutriceuticals Representative
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    Success occurs when everything you have is APPLIED.
    Have you heard about N.O. Uptake? ;-)
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    Quote Originally Posted by Lanbane View Post
    Hmmm i'll be in san diego next week, doesn't themyth live around them parts?
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    Woot, woot!!

    More write-up..... me want more write-up.
    ~ Nothing can kill the Grimace!!


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    Nope I used to live there, I am in northern cali now! Plus, I wouldn't be of any service to you, I still don't even have any Drive!
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    Let's toss around some stack ideas....butclear up now
    RPM STACKS WITH ANYTHING!!! haha what else? Maybe some P-Slin? Annabolic Pump? Incarnate?
    Serve em' Up!
    This way when people ask, we send them here...
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    Can I trade the woman I live with in for some Drive?
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    No X, nobody wants her but you, sorry, the going rate for drive is more than 2 cents. lol
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    Quote Originally Posted by TheMyth View Post
    No X, nobody wants her but you, sorry, the going rate for drive is more than 2 cents. lol
    ouch thats cold
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    Quote Originally Posted by strategicmove View Post
    3.5 kg increased lean mass inside what time frame?
    10-12 weeks
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by EasyEJL View Post
    Do any of the reps have some one hand so I can find out where they live, break in, and steal some?
    I got plenty! come on down man, im in SC!!!!!
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    Quote Originally Posted by EasyEJL View Post
    I can't wait till its available. I miss it, and am jealous of anyone who currently has any...
    I don't think anyone does (except Wedgylx maybe)- I have been out for about 3 weeks




    But don't worry- coming soon
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by MentalTwitch View Post
    Let's toss around some stack ideas....butclear up now
    RPM STACKS WITH ANYTHING!!! haha what else? Maybe some P-Slin? Annabolic Pump? Incarnate?
    Serve em' Up!
    This way when people ask, we send them here...
    Stacks well w/ IGF-2, NeoVar, RPM, X-Factor, very long list....
    Dirk Tanis, BA, MSci
    Chief Operating Officer, Applied Nutriceuticals
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    Quote Originally Posted by ugab37 View Post
    I got plenty! come on down man, im in SC!!!!!
    I stand corrected- I am coming down to steal that **** back from you
    Dirk Tanis, BA, MSci
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    Quote Originally Posted by ugab37 View Post
    I got plenty! come on down man, im in SC!!!!!
    Hmm where in SC?
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    Quote Originally Posted by rms80 View Post
    Stacks well w/ IGF-2, NeoVar, RPM, X-Factor, very long list....
    I think i'm going to do the drive / xfactor combo as part of my next pct. Seems like a nice way to continue gains.
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    Quote Originally Posted by EasyEJL View Post
    I think i'm going to do the drive / xfactor combo as part of my next post cycle therapy. Seems like a nice way to continue gains.
    Definitely...
    Dirk Tanis, BA, MSci
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    Quote Originally Posted by TheMyth View Post
    No X, nobody wants her but you, sorry, the going rate for drive is more than 2 cents. lol
    Uncool.
    Applied Nutriceuticals Representative
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    I am giddy waiting for Drive to arrive.


    "RPM and Drive are a freight train from hell, and they're going strraight up the ass of the competition"
    ~Lanbane, after watching Blades of Glory for the 2nd time.
    Applied Nutriceuticals Representative
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    I want it....now!







    Please....
  35. O.G. Appnut
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    Quote Originally Posted by haiz69 View Post
    I want it....now!







    Please....
    I know what you're saying man...... As soon as all the pieces fall together, Drive will hit the market.
    Then I can build a small stockpile of my new favorite supplement. I will always love and use RPM, but Drive just has that new-girlfriend feel right about now....... hahaha
    Applied Nutriceuticals Representative
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    Never enough
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    Luckily since i'm doing that PAL transformation contest, I couldn't take drive anyhow so its not completely bad. It just needs to be out by november
  37. O.G. Appnut
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    Quote Originally Posted by EasyEJL View Post
    Luckily since i'm doing that PAL transformation contest, I couldn't take drive anyhow so its not completely bad. It just needs to be out by november
    How's your contest coming along Easy? Do you have a set end date?
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    i have like 5 bags of drive still wooohooooo
    toes-on-the-nose.blogspot.com Deployed blogging
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    Quote Originally Posted by EasyEJL View Post
    Luckily since i'm doing that PAL transformation contest, I couldn't take drive anyhow so its not completely bad. It just needs to be out by november
    I hope to start using it ~1 month before my fight in November (wink, wink, nudge, nudge)...
    M.Ed. Ex Phys
    Performax Labs Product Specialist

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    I also want to say the sweet spot for me has been

    3 drive and 2 rpm, without any doubt in this world as honest as my son is alive today this has been the best 1 -2 punch ive had
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