Ok so I have a question about a supplement dosage but to find the answer to my question I have to know this. Is it true that when insulin goes up GH release goes down? and the same thing other way around? or am I completely fukking wrong?!
I was wondering something similar. I know insulin rls lowers Gh not sure if the reverse is true. I also wanted to ask anyone is there a possibility of taking an insulin mimicker + ghenerate preworkout? I love ghenerate for burning fat, my joints are hell without it, and buiding muscle, but I love the strength from the carbs
I, unfortunately, am not familiar with the relationship between GH/Insulin. I will sub for the answer though
Where did you hear GH suppresses insulin? GH promotes insulin-like growth factor (IGF-1) which is homologous to proinsulin, an insulin precursor. Hence GH and insulin are directly related, not inversely related.
btw - IGF-1 is actually a great supplement to take in place of GH. It not only has similar effects but it actually increases the body's sensitivity to natural insulin.
On another forum i believe but i dont trust anywhere else but AM So if spike your insulin you increase your GH release? For example if one takes an insulin mimicker Pre-workout cause of a carbed intra workout your body releases more GH. I've also heard after workout your insulin spikes so after workout your body releases more GH for better recovery, is that correct?
SO, GH will increase insulin but insulin will decrease GH (in a rather simplified model).
This why people think that insulin and GH are inversely related, because usually when your GH is thru the roof you have nearly no insulin and vice versa. However this is because the lack of insulin is invoking GH production, NOT because GH production is shutting down insulin. That is why high GH is seen when insulin is minimal. A ton of insulin will, however, invoke the negative feedback for GH and that is why high insulin yields lower GH.
So, yes, taking a GH or proGH would be better than taking insulin or an insulin mimicker.
I beleive the production of gh and its effects are blunted in the presence of insulin. I know when you shoot gh, a big no no is carbs and insulin within 20 minutes of the injection or it is essentially pointless.
A low carb environment is conducive for optimal GH levels. Conversely, a high carb (insulin release) antagonizes GH release.
However, the relationship described above is based on macro intake and not direct drug use.
Elevated insulin levels (via insulin administration) will adversely impact GH levels. HGH use/injections will cause optimal insulin GROWTH FACTORS like IGF,etc (which are different from Insulin).
GH causes hypoglycemia in many which would support the argument that it lowers insulin sensitivity. If you blood sugar drops, so does your insullin as therre si no "need" for insulin (body will up the glucagon hormone instead; insulin's opposite).
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In order for GH to be anabolic you NEED to inject insulin after the GH. GH is not anabolic without insulin and it also increases blood sugar on its own if taken with carbs so clearly it does something to blunt the function of endo produced GH.
Carbs before is bad and carbs after is bad without insulin but then again GH without insulin is not for growth... For fat loss, no carbs before or after
Every single protocol for mass building I have seen, states to wait until the conversion of gh to igf in the liver occurs, which takes 20 minutes post a IM injection to take insulin. 20 minutes after injecting gh, you shoot slin, eat a big protein/carb meal. I have seen tons of different gh mass building protocols, and never once since that part different.
I'm not concerned, ill stick to the 20 minute rule like I have always read, I know first hand it works amazing.
subd for discussion
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