im looking to lower estrogen, but i dont wanna completely destroy it, as it is necessary for growth and i shed like crazy when i dont have enough, anything that will lower it but not to far??
anything but an ATD. the newest ones are anything with 6-bromo in it and transresveratrol has some AI properties. also a tried and true product is 6-oxo, very cheap in bulk powderim looking to lower estrogen, but i dont wanna completely destroy it, as it is necessary for growth and i shed like crazy when i dont have enough, anything that will lower it but not to far??
i don't think so. pretty sure bromo is more than enough. would be kind of overkill for bothOTC, and 6-oxo made my hair fall out, i tried it a few times a while back, im interested are there any products with both reversitol and 6 bromo??
here is why i want one, last time i went and got blood work done, estro was above normal, but not much, now ever since i had pubertal gyno, my nipples have been sore and sensitive, well just recently i have noticed it has worsened, it hurt more, and when i get blood drawn i pass out so getting blood work all the time is a pain in the a$$, and my doctor is stupid and doesnt believe that they are sore....(retard)
so i wanted to make the "normal", not to low/not to high, so i was wondering if there is anything that would help this, and i am thinking about running divanil (divanex or testabolan v2) and, i have read that raises estro levels aswell as free up test......so i would need it for there aswell
hmmmm, how low of a dose can i go while still seeing results, i just dont want something heavy
are you talking about gaspari novedex xt or nolvedex being the one used to reduce estrogen in cancer patients?if you haven't had a test from the time you started nolvedex xt I'm sure your levels are low or very low using gaspari's novledex xt.I'd wait in till the test results are back than go from there. remember nolvedex xt drops estrogen so low and then estrogen climbs back up....so it depends on how long since you've done nolvedex for estrogen levels to stabilize. I'd say a month or two after your done(not messing with any other hormonal s) and to be sure two-three months after using nolvedex xt(or any estrogen inhibitor)
most normal healthy men don't have to worry about htr(including lower estrogen ) in till forty - fifty years old ,when test starts dropping off bigtime. Most guys freak and think they have bitch tits when in fact its just an extra amount of fat. lose the fat. the more fat you have the more puff you'll carry in your chest. (and yes too much fat causes estrogen levels to go up)
resveratrol is pointless to take orallyMaybe try some of iforces resveratrol it has a interesting ingredient profile
it's because it's natural and the 6-oxo is an AI which keeps levels down. it's not going to raise test a ridiculous amount so you don't have to worry about that. people take AI's during cycle for very androgenic compounds to keep estrogen down. it's not like the raise in test will outpower the 6-oxo.Idont follow this argument about 6 oxo .can anyone explain my point is this --- if using an AI like 6 oxo reduces e and produces more test, then that test has the potential to produce more estrogen , the 6 oxo lowers that , produces more test so more e.It seems to be a vicious circle .Isnt a new base line being produced for both test and e which has been elevated above that it was before supplementing with 6 oxo?
resveratrol is pointless to take orally
If you are worried about estro levels dipping too low, pick one or the other, not both. You don't always need to STACK!!! (That was me yelling at EVERYONE out there!!!)yah, im gunna do hyperdrol x2 and divanex from NP, and the statement i made above is about 6-oxo i have never used nolvadex xt or Novedex...only clomid and 6-oxo....but any way how does my stack sound??
resveratrol is pointless to take orally
i know they don't but how much does that actually help with absorption. does it make it go from like 5% to 10% or like 5% to 90%?I dont think Anabolic Innovations would agree with you on that.(see their Stoked product) Quercetin & Piperine have been included to enhance absorption and bioavailability
well obviously but some things have a higher biovalibility than other things. and if you take say 500mg of vit c and you're body only absorbs like 5mg of it you wouldn't waste your money on it.you could argue how much of anything is absorbed just cos you take 500 mg of vit c it doesnt mean youll absorb that ,that applies with anything
from what i've read. i bought sustain alpha and felt more than with stokedis rez ocay as a transdermal?
Actually, I think TD is a great idea TD. The user feedback on SA sure agrees Orally, unless it is acetylated (or otherwise enhanced like taken with bioperine), the bioavailability is quite low.is rez ocay as a transdermal?
yes i think everybody knows that piperine and others can help increase absorbtion. nobody was disputing thatOn absorbtion of transreservatrol , the study below suggest certain ingredients enhance biovailability
De Santi et al. Xenobiotica 30, 609-617 (2000).
Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum
Abstract
1. Resveratrol, a polyphenolic compound present in grapes and wine, has beneficial effects against cancer and protective effects on the cardiovascular system. It is present in the diet, and the hepatic and duodenal sulphation might limit the bioavailability of this compound. The aim was to study the sulphation of resveratrol in the human liver and duodenum. 2. A simple and reproducible radiometric assay for resveratrol sulphation was developed. It employed 3'-phosphoadenosine-5'-phosphosulphate-[S-35] as the sulphate donor and the rates of resveratrol sulphation (mean +/- SD, pmol/min/mg cytosolic protein) were 90+/-21 (liver, n = 10) and 74+/-60 (duodenum, n = 10, P = 0.082).3. Resveratrol sulphotransferase followed Michaelis-Menten kinetics and K-m, (mean+/-SD; mu M) was 0.63=/-0.03 (liver, n = 5) and 0.50+/-0.26 (duodenum, n = 5, p = 0.39) and V-max (mean+/-SD, pmol/min/mg cytosolic protein) were 125+/-31 (liver, n = 5) and 129+85 (duodenum, n = 5, p = 0.62).4. Resveratrol sulphation was inhibited by the flavonoid quercetin, by mefenamic acid and salicylic acid, two commonly used non-steroidal anti-inflammatory drugs. IC50 of resveratrol sulphation for quercetin was 12+/-2 pM (liver) and 15+/-2 pM (duodenum), those for mefenamic acid were 24+/-3 nM (liver) and 11+/-0.6 nM (duodenum), and those for salicylic acid were 53+/-9 mu M (liver) and 66+/-4 mu M (duodenum).5. The potent inhibition of resveratrol sulphation by quercetin, a flavonoid present in wine, fruits and vegetables, suggests that compounds present in the diet may inhibit the sulphation of resveratrol, thus improving its bioavailability. http://serials.cib.unibo.it/cgi-ser/...iew=arti coli
whilest not directly talking about transreservatrol, another polyphenol curcumin was tested for absorbtion using piperine
the study follows
Bioprene has been shown to enhance the serum concentration/bioavailability of polyphenols, by significantly blunting the extensive intestinal and/or hepatic glucuronidation and sulfation. The lecethin should speed-up the entire process via enhanced dissolution kinetics and transit times.
"Concomitant administration of piperine 20 mg produced much higher concentrations from 0.25 to 1 h post drug (P < 0.01 at 0.25 and 0.5 h; P < 0.001 at 1 h), the increase in bioavailability was 2000%."
"The study shows that in the dosages used, piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects."
Planta Med. 1998 May;64(4):353-6.
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.
http://www.ncbi.nlm.nih.gov/pubmed/9619120
why worry about it, i thought u were going with the hyperdrol?it was still useful to me, i was wondering about both of the ingredients used to help bioavailability
haha u lazy bastardyah..........so, i want to know more about the world of supplements....and i didnt feel like searching my self so it was helpful
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