As in other parts of nature, the human body is regulated by the storage and expenditure of energy – this process is at the heart of each one of the body’s metabolic processes, from growth, to vision, to digestion, to excrement. As an evolutionary response, the human body became a finely tuned complex of mechanisms meant to opportunistically metabolize energy – that is, store energy for future use, or during times of adequate intake to facilitate growth (anabolic response); or, to produce energy from stored nutrients in times of inadequate intake (catabolism). Sounds like a sweet deal, huh? Your cells demand energy, or reject it, and your body metabolizes nutrients accordingly! However, a certain problem has arisen, leading to issues of adipogenesis – the modern diet!
Quite simply, the evolution of the human body’s energy metabolism pathways were born of necessity: our ancestors scarcely ate high levels of ligands, choosing instead animal proteins and lipids, while simultaneously encountering long bouts of famine. In this respect, our storage pathways, especially in terms of adipocytes (fat cells) were necessary, as whatever nutrients were encountered needed to be fully utilized. However, these once ‘life-saving’ energy mechanisms are now ‘diet-killing’ frustrations! With a fitness diet, ample with caloric energy for cells, these mechanisms now lead to the hypertrophy of fat cells, via the binding to blood lipids, GLUT4 upregulation leading to adipocyte glucose storage, and deregulation of energy expenditure messengers. The solution: The Six Pack Stack!
Both Anabolic Pump and ReCreate are veritable titans of energy homeostasis – regulating all of the body’s major metabolic pathways to assist in achieving the most favorable tissue composition possible! Here is how:
As much as Anabolic Pump is a supplement meant to achieve glucosehomeostasis, and thought of as such, its success is due to its ability to mitigate energy expenditure pathways within the body. Specifically, Berberine's direct stimulation of AMPk, a master regulatory 'switch', so to speak, of intracellular energy metabolism. In normal (i.e., non-supplemented) states of exercise, AMPk plays a vital role in maintaining cellular energy, via both a glycolytic and oxidative role - that is, initially inducing glycolysis to provide energy for cellular reactions, and oxidizing fatty acids in longer bouts. This occurs due to an increase in the extracellular AMP:ATP ratio. As ATP increases, the body is in extreme demand for cellular energy during exercise. At this point, AMPk upregulates energy producing mechanisms (translocation of GLUT4, FFA oxidation) and downregulates energy consuming pathways (protein and fatty acid synthesis).
This glycolytic and oxidative manners of energy exchange is why AP provides tangible body composition changes - delivering intracellular messages, at the genetic level (via PPAR family) for adipocytes to oxidize and expend energy, while signaling for myocytes to do the complete opposite. Amazingly, the regulation of energy metabolism is not exclusive to Berberine, but is accomplished by Lagerstroemia Speciosa as well; constituents within LS have been shown to selectively regulate proteins responsible for the induction of GLUT4 in myocytes, while denying the same process in adipocytes. Further, the PPAR family of lipid-binding proteins mentioned previously in relation to Berberine are mitigated by LS as well! Simply put, Anabolic Pump genetically alters the mechanisms our body uses to maintain energy homeostasis – effectively upregulating energy expenditure –very selectively – in order to produce body composition changes!
The amount of energy expenditure pathways that ReCreate modulates is quite astounding! In respects to the AMPk discussion had previously, ReCreate increases, very prominently, levels of cAMP and ATP – key messengers of extracellular energy metabolism; in terms of nutrient synthesizing, ReCreate vastly increases levels of T3, the active Thyroid Hormone responsible for the metabolism of lipids, proteins, and carbohydrates; in terms of energy production and stress response, ReCreate inhibits the production of Cortisol at the enzymatic level, ensuring that catabolic response Is attenuated in skeletal muscle, thereby further sensitizing muscle cells to Insulin, ensuring nutrient metabolism occurs efficiently, and that the body remains in positive nitrogen balance; and finally, in a lipid-specific respect, ReCreate even mitigates HSL (hormone sensitive lipase), an enzyme responsible for the induction of lipolysis dependent on the hormone’s which ReCreate is already modulating!
Plainly, the combination of Anabolic Pump and ReCreate alters your body’s natural energy pathways at the genetic level