Truthornothin's Ursobolic Log The Whole Truth and Nothing But the Truth! - AnabolicMinds.com

Truthornothin's Ursobolic Log The Whole Truth and Nothing But the Truth!

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    Truthornothin's Ursobolic Log The Whole Truth and Nothing But the Truth!


    I started Ursobolic this morning.

    I am a 46 year old maleI've been working out for approximately 20+ years

    6'1" 204 lbs
    Measurements:

    Bi's: 18" Right 17.75" Left

    Chest 49'

    stomach 34

    Thighs 26.5

    BF 8%




    My diet is on the low carb side but not totally carb deficient

    Macros: 50%protein 25%carbs 25% fat, I vary my diet according to my look. If I am looking flat I bump up the carbs and reduce the fats, if I feel that I am gaining fat I drop the carbs,



    I just came off ostarine. I am using this in PCT in hopes of maintaining my gains and becoming perhaps leaner or at the very least able to eat a reasonable amount without losing my definition. I just came off a cut and unfortunately a bad personal situation wreck my last week, so I am not as lean as I was the week prior. Need 50 post to post pics? I've already posted pics some time ago I am puzzled on this one, guess I had better start posting

    I am going to run this for 8 weeks at the 9 cap a day dosage.
    I intend to try to recomp perhaps gaining a few pounds of muscle while losing a little more fat. I think for this compound the camera will be the best judge of results. I will post weekly pics after week 2. That is going to be the difficult part of this log getting through two weeks of no expected results.


    Observations:
    Today just started taking Ursobolic and appetite is definitely reduced. Could be placebo effect as I was expecting that. I also noticed I was hot as hell at work and sweating like a pig, have the ac on now and still sweating. It appears this stuff has an immediate effect on core temp. That, I wasn't expecting.

    Will not log diet today as basically I didn't eat, still stressed over my personal issue drank 5 protein shakes 50 grams each whey only

    Took my Ursobolic doses with 2 tbsp of natty peanut butter each.

    Workout:

    Back and bi's
    very heavy, No cardio Truthornothin' does not do cardio. Tomorrow will post pics and will be back on track nutritionally will post detailed nutrition intake as I weigh my food so this'll be pretty precise. Hope some of you sign on for the ride.

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    First one INNNN
    SNS - Serious Nutrition Solutions
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    Subbed!! Everything looks good so far. Let's see how good this product really is!!!!
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    In for The Whole Truth and Nothing But the Truth
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    Ursobolic Day 2


    Day Two:

    Took 3 caps 3 times over the course of the day

    Nutrition:

    Breakfast:

    4 whole eggs
    25 grams of oatmeal
    8 oz V-8 juice

    Mid Morning:

    50 Grams Whey Protein
    30 grams of almonds

    Afternoon:
    50 grams of Whey Protein
    30 grams almonds

    Pre Workout:

    2 servings White Flood
    1 serving Purple Wraath

    Post Work Out:

    50 Grams of protein
    30 grams oat starch

    Workout:

    Today was chest, delts and tris

    I did my standard workout nothing new to report its only day two. I was able to work chest hard for the first time in a while as I've been nursing an injured shoulder and elbow was able to push for the first time in a month on chest and it felt good. Shoulders and tris good too.

    Observations:

    Appetite suppression, but not extreme just not always hungry like I usually am. I love to eat stay this lean is hard.

    Heat, noticed that I still feel warmer and am sweating more profusely That is all, I am not going to say I feel all these effects from it at this point . This is my log but its for your benefit. Tell me what information you are looking for and I'll share it. If you want more detailed work out info let me know. Here are the before pics Name:  2011_0930picsnew0027.JPG
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    Nice update. And glad to see you will be posting before and after pictures (no homo)
    I hope you are sticking to your regular diet... That way we could gauge the effects solely from Ursobolic

    Or are you going to change it up much?
    SNS - Serious Nutrition Solutions
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    Quote Originally Posted by ConcreteConny
    Nice update. And glad to see you will be posting before and after pictures (no homo)
    I hope you are sticking to your regular diet... That way we could gauge the effects solely from Ursobolic

    Or are you going to change it up much?
    Interested to hear your reply and props on the pics. When I get back on the computer I'll sen you some reps.
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    Quote Originally Posted by ConcreteConny View Post
    Nice update. And glad to see you will be posting before and after pictures (no homo)
    I hope you are sticking to your regular diet... That way we could gauge the effects solely from Ursobolic

    Or are you going to change it up much?
    Pics are important, without them you can say anything you want, pics are the proof. My diet I actually intend to increase calories after week 2 to intentionally test the effects of this compound I can cut on my own with out a supp if I just have to cut my calories. I am hoping I can be looser with my diet and still keep my abs, that would be worth the price Ya' know?
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    Quote Originally Posted by mattrag View Post
    Interested to hear your reply and props on the pics. When I get back on the computer I'll sen you some reps.
    Thanks man, I can use the reps. I intend to make this a good test. Again anything you guys want me to keep track of or that you want to know that I am not posting let me know. I am open to input.
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    Quote Originally Posted by truthornothin
    Thanks man, I can use the reps. I intend to make this a good test. Again anything you guys want me to keep track of or that you want to know that I am not posting let me know. I am open to input.
    Will do and good luck with the run. I'll check in as often as I can.
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    Quote Originally Posted by truthornothin View Post
    My diet I actually intend to increase calories after week 2 to intentionally test the effects of this compound I can cut on my own with out a supp if I just have to cut my calories. I am hoping I can be looser with my diet and still keep my abs, that would be worth the price Ya' know?
    That sounds like a great plan
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    I want this log to be informative too check out this article, at my age I am just as interested in Ursobolic's many health benefits as I am its muscle building fat burning effects
    J Pharm Pharmacol. 2008 Oct;60(10):1347-54.
    The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis models.
    Kang SY, Yoon SY, Roh DH, Jeon MJ, Seo HS, Uh DK, Kwon YB, Kim HW, Han HJ, Lee HJ, Lee JH.
    Source
    Department of Veterinary Physiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul, South Korea.
    Abstract
    Ursolic acid (UA) is pentacyclic triterpenoic acid that naturally occurs in many medicinal herbs and plants. In this study, we examined the possible suppressive effect of UA extracted from Oldenlandia diffusa on zymosan-induced acute inflammation in mice and complete Freund's adjuvant (CFA)-induced arthritis in rats. UA treatment (per oral) dose-dependently (25-200 mg kg(-1)) suppressed zymosan-induced leucocyte migration and prostaglandin E2 (PGE(2)) production in the air pouch exudates. Since the maximal effective dose of UA was 50 mg kg(-1) in the zymosan experiment, we used this dose of UA in a subsequent study using an adjuvant-induced rheumatoid arthritis model. UA treatment (50 mg kg(-1), per oral, once a day for 10 days) was started from day 12 after adjuvant injection. UA dramatically inhibited paw swelling, plasma PGE(2) production and radiological changes in the joint caused by CFA injection. Moreover, UA significantly suppressed the arthritis-induced mechanical and thermal hyperalgesia as well as the spinal Fos expression, as determined by immunohistochemistry, which was increased by CFA injection. In addition, overall anti-arthritic potency of UA was comparable with ibuprofen (100 mg kg(-1), oral) while UA did not induce significant gastric lesions as compared with the ibuprofen treatment group. These findings strongly suggest that UA is a useful suppressive compound for rheumatoid arthritis treatment with low risk of gastric problems.

    PMID: 18812028 [PubMed - indexed for MEDLINE]
    Publication Types, MeSH Terms, Substances

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    Great log so far
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    Quote Originally Posted by Ev52 View Post
    Great log so far
    Thanks, if you have any input feel free, I want to make this the definitive Ursobolic log, If I miss something point it out.
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    Subscribed.
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    Quote Originally Posted by DevotedDad View Post
    Subscribed.
    welcome aboard
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    Performing your original search, ursolic acid liver ethanol, in PubMed will retrieve 3 records.
    Life Sci. 2006 Jan 11;78(7):713-8. Epub 2005 Aug 30.
    Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats.
    Saravanan R, Viswanathan P, Pugalendi KV.
    Source
    Department of Biochemistry, Faculty of Science, Annamalai University, Annamalai Nagar 608 002, Tamilnadu, India.
    Abstract
    Ursolic acid is a triterpenoid that exists in nature and is the major component of some traditional medicinal herbs. In this study, ursolic acid has been evaluated for its hepatoprotective effect against chronic ethanol-mediated toxicity in rats. Ethanol administration (7.9 g/kg/day) for 60 days resulted in increased oxidative stress, decreased antioxidant defense and liver injury. It also negatively affected the serum total protein, albumin and A/G ratio. Subsequent to the experimental induction of toxicity (i.e. after the initial period of 30 days) ursolic acid treatment performed by co-administering ursolic acid (10, 20 and 40 mg/kg body weight) for 30 days along with the daily dose of ethanol. While this treatment causing a significant improvement in body weight, food intake and serum protein levels, it decreases serum aminotransferase activities (aspartate aminotransferase and alanine aminotransferase) and total bilirubin levels. Ursolic acid improved the antioxidant status of alcoholic rats, which is evaluated by the decreased levels of lipid peroxidation markers in plasma (thiobarbituric acid reactive substances and lipid hydroperoxides) and increased levels of circulatory antioxidants such as reduced glutathione, ascorbic acid and alpha-tocopherol. Histopathological observations were also in correlation with the biochemical parameters. The activity of ursolic acid (20 mg/kg) compares well with silymarin, a known hepatoprotective drug, and seems to be better in certain parameters. The protective effect of ursolic acid is probably related to its antioxidant activities.

    PMID: 16137716 [PubMed - indexed for MEDLINE]
    Publication Types, MeSH Terms, Substances

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    Hmmm! May be more protective than Milk Thistle, Seems like an excellent PCT choice
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    Quote Originally Posted by truthornothin

    Hmmm! May be more protective than Milk Thistle, Seems like an excellent PCT choice
    Interestingly this makes me want to take more methylated phs. Haha

    Man if I had known that I would have ordered it @14.99 and just run two bottles for on month...
    Sub it out for my ala/nac purchase this month. Lol
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    In very intrested as I have 8 bottles coming
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    Quote Originally Posted by dollar662
    In very intrested as I have 8 bottles coming
    Omfg. Loggin it?
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    Great find on the article bubba. I also like the plans for this run. This compound looks very promising for us elder gents.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    Quote Originally Posted by mattrag View Post
    Omfg. Loggin it?
    Not sure yet , I dont really have the time right now with work to log. Will see though ... Havent decided dose thinking 12 a day

    and sorry not trying to jack thread
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    Quote Originally Posted by dollar662 View Post
    Not sure yet , I dont really have the time right now with work to log. Will see though ... Havent decided dose thinking 12 a day

    and sorry not trying to jack thread
    Its all good, Hope you follow along
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    Plan looks good. I'm in for this one
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    Day 3

    Took 3 caps 3 times over the course of the day

    Nutrition:

    Breakfast:

    4 whole eggs
    30 grams of barley
    8 oz V-8 juice

    Mid Morning:

    50 Grams Whey Protein
    30 grams of walnuts

    Afternoon:
    50 grams of Whey Protein
    30 grams almonds

    Pre Workout:

    2 servings White Flood
    1 serving Purple Wraath

    Post Work Out:

    50 Grams of protein
    30 grams oat starch

    Dinner:

    300 grams Grilled Chicken
    40 grams rice
    Broccoli


    Workout:

    Today was leg day, Worked out at home today, Squats To 325 , leg extensions , and leg curls. Did high reps and numerous sets got a good leg pump and a back twinge, worked abs and done. Pretty much my standard workout no changes good or bad


    Observations

    Nothing new to report, just minor appetite suppression and the sweats. Is anybody else noticing this. I am taking it as a good sign something is happening especially since it was unanticipated . More tomorrow folks
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    Anti Cancer Study, Showing COX2 suppression by ursolic acid. Appears some serious anti-inflammatory action here

    Ursolic Acid Inhibits Cyclooxygenase-2 Transcription in Human Mammary Epithelial Cells 1
    Kotha Subbaramaiah, Pedro Michaluart, Michael B. Sporn, and Andrew J. Dannenberg2
    + Author Affiliations

    Department of Medicine [K. S., A. J. D.] and Surgery [K. S., A. J. D.], New York Presbyterian Hospital-Cornell, New York, New York 10021, USA; Anne Fisher Nutrition Center [K. S., A. J. D.] at Strang Cancer Prevention Center, New York, New York 10021, USA; and Head and Neck Service [P. M.], Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA, and Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA [M. B. S.]
    Abstract

    We investigated the effects of ursolic acid, a chemopreventive agent, on the expression of cyclooxygenase-2 (COX-2) in phorbol 12-myristate 13-acetate (PMA)-treated human mammary and oral epithelial cells. Treatment with ursolic acid suppressed PMA-mediated induction of COX-2 protein and synthesis of prostaglandin E2. Ursolic acid also suppressed the induction of COX-2 mRNA by PMA. Nuclear run-offs revealed increased rates of COX-2 transcription after treatment with PMA, an effect that was inhibited by ursolic acid. Transient transfections indicated that the effects of PMA were mediated by a cyclic AMP response element in the COX-2 promoter. Ursolic acid inhibited PMA-mediated activation of protein kinase C, extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinases. Treatment with PMA increased activator protein-1 activity and the binding of c-Jun to the cyclic AMP response element of the COX-2 promoter, effects that were blocked by ursolic acid. These data are important for understanding the anticancer and anti-inflammatory properties of ursolic acid.

    Footnotes

    The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked advertisement in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
    ↵1 This work was supported in part by NIH Grant P01 CA29502 (to K. S.), the Cancer Research Foundation of America (to K. S.), the American Institute for Cancer Research (to A. J. D.), and the Lawrence A. Miller Memorial Foundation.
    ↵2 To whom requests for reprints should be addressed, at New York Presbyterian Hospital-Cornell, 525 East 68th Street, Room F-206, New York, NY 10021. Phone: (212) 746-4403; Fax: (212) 746-4885; E-mail: ajdannen@mail.med.cornell.edu.
    Received October 20, 1999.
    Accepted February 28, 2000.
    ©2000 American Association for Cancer Research.
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    Like the articles! You using swedish oat starch? Love that stuff.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    Quote Originally Posted by AZMIDLYF View Post
    Like the articles! You using swedish oat starch? Love that stuff.
    Yes I do, the place I get it from adds flavorings, electrolytes vitamins, I make my own MRP's
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    True Protein?
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    Yes, was't sure if AM likes us to post other suppliers, but yes I order a good bit from them, they can be pricey but I like having ultimate control over what I am taking
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    Quote Originally Posted by truthornothin View Post
    Yes, was't sure if AM likes us to post other suppliers, but yes I order a good bit from them, they can be pricey but I like having ultimate control over what I am taking
    They used to be on here but have since left and I agree with you on both points regarding them.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    Day 4

    Took 3 caps 3 times over the course of the day

    Nutrition: Cheat Day

    Breakfast:

    4 whole eggs
    35 grams oatmeal with 3 tbsp brown sugar cinnamon and raisins LOTS!!! its cheat day
    8 oz V-8 juice
    5 cups of coffee and about 8tbsp half and half

    Mid Morning:

    50 Grams Whey Protein
    30 grams of walnuts
    1 cup gourmet Granola...Locally made Pecan Chocolate Cherry mmm mmmm MMMM!

    Afternoon:
    50 grams of Whey Protein
    30 grams almonds
    Half cup Granola

    Pre Workout:

    1 serving AI Maniac
    1 serving Purple Wraath

    Post Work Out:

    50 Grams of protein
    30 grams oat starch

    Dinner:

    300 grams Grilled Chicken
    70 grams of beans smothered in cheese and bacon tomato sauce and olive oil
    1/4 cup granola



    Workout:

    Today was back and bi's I love cheat day workouts. Even though I had a back twinge from yesterday turned in a solid workout,

    Unassisted chins 1 x 24 1x20 1x16 1 x10 3 x 8 3x5 Too many sets probably but felt strong did pulldowns on Nautilus unilateral plate loaded pull down machine up to 4 45's each side for three sets of 6, pyramided up and down, didn't do low rows because of a back twinge, used machine that replicates the movement of a low row but braces the core. Went way heavy, felt good. Did a couple other machines got a good back pump.

    Bis used cables, up to stack for sets of 8. Preacher machine plate loaded, with 2 45's and 2 tens 6 sets of 8-10 then a seated curl machine to 120. My biceps were so pumped it felt like the skin would split.

    Observations:

    Definitely ate above maintenance calories today, I give myself 1 cheat day a week, I usually cheat harder lol. But I do intend at week two to sloppy up my diet. I am doing to risk my six pack to give this a true test. I usually get a good pump on high carb days but today it has stayed. Not sure if the Ursobolic is the cause but it is different than normal so I am reporting it. Its been hours and I still have a good pump. The Truth likey

    Still sweating profusely and still have a slightly surpressed appetite but mostly in the day, I forget about breakfast until late and forget lunch but at night my appetite comes roaring to life. Thats all for this evening more tomorrow
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    Nice Updates
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    Nice workout. Better safe than sorry on back issues that's for sure. Oatmeal and raisins is one of my favorite things and that granola sounds rediculous!
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    truthornothin's Avatar
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    Quote Originally Posted by AZMIDLYF View Post
    Nice workout. Better safe than sorry on back issues that's for sure. Oatmeal and raisins is one of my favorite things and that granola sounds rediculous!
    You got that right, The granola is ridiculous. I get all my cheat day supplies from www.bigbossbaking.com It is owned by a local lady, she used to be a figure competitor, all her cookies brownies whoopie pies and gourmet granola are cheat day worthy. I figure if your gonna cheat cheat delicious
  37. Senior Member
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    Took 3 caps 3 times over the course of the day

    Nutrition: Cheat Day

    Breakfast:

    4 whole eggs
    1 large Peach
    8 oz V-8 juice
    5 cups of coffee and about 8tbsp half and half

    Mid Morning:

    50 Grams Whey Protein
    30 grams of walnuts


    Afternoon:
    50 grams of Whey Protein
    30 grams almonds


    Dinner:

    275 grams Grilled Chicken
    70 grams of beans smothered in cheese and bacon tomato sauce and olive oil

    Cheat Snack:
    Was invited to Greek Orthodox function by friends, tried to resist delicious Greek Food FAILED!!! Ate one slice Pastitsio, Fasolakia(green beans in tomato sauce with garlic and olive oil) and one small ok big piece of baklava....going to put this supp to the test lol

    Before Bed:
    50 grams whey protein
    ! cup Fiber One
    1/2 cup milk


    Observations:

    Today was my day off the gym, did nothing physical, back twinge is gone. Folks, I am not sure if I am getting more ripped but even with my currrent indulgences, I may look a might trimmer, and my muscles are way fuller. Talked to the gf on skype and out the blue she asked if I'd gotten bigger. I told her I was just happy to see her lol wink wink, But seriously my muscle bellies are fuller possibly from the partitioning effects of the Ursolic acid. She hasn't seen me in a week so she'd be apt to notice a difference and she did. Still not hungry during the day still ravenous at night and still sweating when everyone else is cold. This stuff is doing something. Tomorrow Pecs, Delts and Tris
  38. Senior Member
    truthornothin's Avatar
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    Interesting article. Shows Ursolic acid as a glucose moderator and a cholesterol reducer
    Metabolism. 2010 Apr;59(4):512-9. Epub 2009 Oct 28.
    Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice.
    Jang SM, Kim MJ, Choi MS, Kwon EY, Lee MK.
    Source
    Department of Nutrition Education, Graduate School of Education, Sunchon National University, Suncheon 540-742, Republic of Korea.
    Abstract
    The effects of ursolic acid on the polyol pathway and glucose homeostasis-related metabolism were examined in the livers of streptozotocin (STZ)-induced diabetic mice fed a high-fat (37% calories from fat) diet for 4 weeks. Male mice were divided into nondiabetic, diabetic control, and diabetic-ursolic acid (0.05% wt/wt) groups. Diabetes was induced by the injection of STZ (200 mg/kg body weight, intraperitoneally). Although an ursolic acid supplement lowered the blood glucose level, it did not affect the plasma leptin and adiponectin levels. The present study shows that the blood glucose levels have a positive correlation with the hepatic sorbitol dehydrogenase activities (r = 0.39, P < .05). Ursolic acid significantly inhibited sorbitol dehydrogenase activity as well as aldose reductase activity in the liver. The supplementation of ursolic acid significantly increased glucokinase activity, while decreasing glucose-6-phosphatase activity in the livers of STZ-induced diabetic mice. Ursolic acid significantly elevated the hepatic glycogen content compared with the diabetic control group. Supplementation with ursolic acid significantly lowered the plasma total cholesterol, free fatty acid, and triglyceride concentrations compared with the diabetic control group, whereas it normalized hepatic triglyceride concentration. A negative correlation was found between the hepatic triglyceride concentration and blood glucose levels (r = -0.50, P < .01) in regard to insulin-dependent diabetic mice. The hepatic fatty acid synthase activity was significantly lower in the ursolic acid group than in the diabetic control group, whereas hepatic fatty acid beta-oxidation and carnitine palmitoyltransferase activities were significantly higher. These results indicate that ursolic acid may be beneficial in preventing diabetic complications by improving the polyol pathway as well as the lipid metabolism and that it can function as a potential modulator of hepatic glucose production, which is partly mediated by up-regulating glucose utilization and glycogen storage and down-regulating glyconeogenesis in the liver.

    Copyright 2010 Elsevier Inc. All rights reserved.

    PMID: 19846180 [PubMed - indexed for MEDLINE]
    Publication Types, MeSH Terms, Substances

    LinkOut - more resources
  39. Diamond Member
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    The facts just keep getting better and better on this compound! I like what I'm reading in these studies and your experience with it so far. Also glad to hear the back is coming along.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
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    This supp looks great. Reminds me if all the good this trans rev had shown. But of course low bio avail.
    Hopefully this dosing protocol is enough. I bought four bottles to run in my transaderm pct.
    RecoverBro ELITE
  

  
 

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