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PHASE 2 with IGF, MGF, Endo Amp, White Flood and some Prime has begun!
This log will be different from anything else I have seen on here. It will include REAL sarms and someone completely trying to restart many major systems of their body at once. Interested yet? Below are just some of the supplements to be logged!
I have been on this board for a few years but started on other boards years before that. I discovered super supplements early on, too early. I tried many combos of supplements and super supplements and was always a hard gainer. I am not the ecto type, more like endo - skinny fat. I am very insulin resistant, think I may acutally be diabetic and have problems with t3 (probably from being diet conscious since age 15.)
I have been as large as 240 with some blubber to as ripped as 200lb at sub 6% (more like 5ish). I've done more stacks of supps and super supps than I would care to admit. Overall nothing worked amazingly well.
I got myself rahter out of shape and started a major rebuilding project around April. things went great. With the help of Lyle McDonalds Ultimate diet 2.0 which I altered to a more ketogenic diet I was able to get ripped. Unfortunetly somethign was awry with my water and it only really showed on PGCL (Force of Green saw it ha - no pics from then unfortunetly). Unfortunetly though none of this is maintainable. My genetics just don't allow it. I don't discuss what I take exactly but I have used far to many super sups over this time, MASSIVE amounts of stimulants and t3.
Right now I am just fed up. my adrenals simply cant take this anymore. No stims effect me, NOTHING. with enough stims my heart will get pounding but no mental high. I use to nearly breakdown from geranium now I can take it and sleep, and thats just one example. Also I am super stressed all day and can't ever sleep.
I have begun adding carbs back in at 150-200 grams a day and have begun tapering off super supps while i save money for a proper pct. Also have begun tapering down my t3 doses.
All carb meals will be taken with 900mg Yellow Gold and 100mg 20% Banaba
Week 1-4
HERE come the SARMS and IGF/MGF!
Note PegMGF is over a year old - may be denatured some but is still lypholized so should be decent
Week 7,9,11,13 - 40-60mcg Receptor grade IGF Post WO - 4 times a week
Week 6,8,10,12 - 500mcg PegMgf Post WO - 4 times a week
Obviousoly this is FAR in the future BUUUUT My general plan is
PLEASE DO NOT ASK ME FOR SOURCES OF ANY OF THE PRODUCTS! - If you can't get it at NP it doesn't exist!
I hope to follow this log as a way to stay motivated over a 5 month period.
I will reserve the posts below for updates and pictures.
Pharmacodynamics of selective androgen receptor modulators.
Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT.
Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
The present study aimed to identify selective androgen receptor modulators (SARMs) with in vivo pharmacological activity. We examined the in vitro and in vivo pharmacological activity of four chiral, nonsteroidal SARMs synthesized in our laboratories. In the in vitro assays, these compounds demonstrated moderate to high androgen receptor (AR) binding affinity, with K(i) values ranging from 4 to 37 nM, and three of the compounds efficaciously stimulated AR-mediated reporter gene expression. The compounds were then administered subcutaneously to castrated rats to appraise their in vivo pharmacological activity. Androgenic activity was evaluated by the ability of these compounds to maintain the weights of prostate and seminal vesicle, whereas levator ani muscle weight was used as a measure of anabolic activity. The maximal response (E(max)) and dose for half-maximal effect (ED(50)) were determined for each compound and compared with that observed for testosterone propionate (TP). Compounds S-1 and S-4 demonstrated in vivo androgenic and anabolic activity, whereas compounds S-2 and S-3 did not. The activities of S-1 and S-4 were tissue-selective in that both compounds stimulated the anabolic organs more than the androgenic organs. These two compounds were less potent and efficacious than TP in androgenic activity, but their anabolic activity was similar to or greater than that of TP. Neither S-1 nor S-4 caused significant luteinizing hormone or follicle stimulating hormone suppression at doses near the ED(50) value. Thus, compounds S-1 and S-4 were identified as SARMs with potent and tissue-selective in vivo pharmacological activity, and represent the first members of a new class of SARMs with selective anabolic effects.
PMID: 12604714 [PubMed - indexed for MEDLINE]
THE HOOK!
This log will be different from anything else I have seen on here. It will include REAL sarms and someone completely trying to restart many major systems of their body at once. Interested yet? Below are just some of the supplements to be logged!
- Cre-02 by MST
- Cordygen5 by MST (possibly VO2 as well)
- REAL Sarms!! - (s-4)
- EndoAmp and Toco-8 and Sustain Alpha by Primordial
- Adaptogen Blend
- 20% Colosoric Acid Banaba!
- High dose Yellow Gold
- Receptor grade IGF
- Reset AD
- Thyroid Energy by Now and Lugols Iodine
History
I have been on this board for a few years but started on other boards years before that. I discovered super supplements early on, too early. I tried many combos of supplements and super supplements and was always a hard gainer. I am not the ecto type, more like endo - skinny fat. I am very insulin resistant, think I may acutally be diabetic and have problems with t3 (probably from being diet conscious since age 15.)
I have been as large as 240 with some blubber to as ripped as 200lb at sub 6% (more like 5ish). I've done more stacks of supps and super supps than I would care to admit. Overall nothing worked amazingly well.
Current
I got myself rahter out of shape and started a major rebuilding project around April. things went great. With the help of Lyle McDonalds Ultimate diet 2.0 which I altered to a more ketogenic diet I was able to get ripped. Unfortunetly somethign was awry with my water and it only really showed on PGCL (Force of Green saw it ha - no pics from then unfortunetly). Unfortunetly though none of this is maintainable. My genetics just don't allow it. I don't discuss what I take exactly but I have used far to many super sups over this time, MASSIVE amounts of stimulants and t3.
Right now I am just fed up. my adrenals simply cant take this anymore. No stims effect me, NOTHING. with enough stims my heart will get pounding but no mental high. I use to nearly breakdown from geranium now I can take it and sleep, and thats just one example. Also I am super stressed all day and can't ever sleep.
I have begun adding carbs back in at 150-200 grams a day and have begun tapering off super supps while i save money for a proper pct. Also have begun tapering down my t3 doses.
The Outline
All carb meals will be taken with 900mg Yellow Gold and 100mg 20% Banaba
Phase 1 - Weeks 1-6 - Adrenal and thyroid Recover
Week 1-4
- Now Rhodiola - 500mg x 3
- Bacopa - Dosing TBD - 2/3 x day
- Holy Basil - 450mg x 3
- 1-Carboxy - Dosing TBD Before bed (2g?)
- NOW Thyroid Energy - Label dosing
- Lugols Iodine - 4 drops ED
- Colleus - 40-60mg actives 2-3 x day
- Reset AD - 3 x day
- Cordygen5 - 2 caps pre-wo / 1 in AM
- CRE-02 - 3 caps pre-wo
- Personal blended pre-WO mix (GMS, ALCAR tyrosine, Chocamine and AAKG)
- Tyrosine and ALCAR ro energy as needed
- Toco-8(starting week 2 or 3)
Phase 2 - Weeks 5/6-11/12 - PCT for HPTA
HERE come the SARMS and IGF/MGF!
- Toremifen Citrate - 90mg to 60mg - 6 weeks
- Clomid 50 mg ED - 6 weeks
- SARM S-4 - TBD - 150-180mg ED - 6 weeks
- Endo amp - 2400mg (1.5 Label) - 6 weeks
- Adaptogen blend from above + Relora
- CONTINUE FROM ABOVE - Lugols, tyrosine, alcar, pre-wo blend, hopefully cre-02 - any other I may have forgotten ha!
Note PegMGF is over a year old - may be denatured some but is still lypholized so should be decent
Week 7,9,11,13 - 40-60mcg Receptor grade IGF Post WO - 4 times a week
Week 6,8,10,12 - 500mcg PegMgf Post WO - 4 times a week
Phase 3 - Weeks13-20 - Moving More Towards the light
Obviousoly this is FAR in the future BUUUUT My general plan is
- Sutain Alpha / Demacrine
- Lean X-treme
- Some IGF in the last 3 weeks
Final Words from Outline
PLEASE DO NOT ASK ME FOR SOURCES OF ANY OF THE PRODUCTS! - If you can't get it at NP it doesn't exist!
I hope to follow this log as a way to stay motivated over a 5 month period.
I will reserve the posts below for updates and pictures.
Sarms Research
Pharmacodynamics of selective androgen receptor modulators.
Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT.
Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
The present study aimed to identify selective androgen receptor modulators (SARMs) with in vivo pharmacological activity. We examined the in vitro and in vivo pharmacological activity of four chiral, nonsteroidal SARMs synthesized in our laboratories. In the in vitro assays, these compounds demonstrated moderate to high androgen receptor (AR) binding affinity, with K(i) values ranging from 4 to 37 nM, and three of the compounds efficaciously stimulated AR-mediated reporter gene expression. The compounds were then administered subcutaneously to castrated rats to appraise their in vivo pharmacological activity. Androgenic activity was evaluated by the ability of these compounds to maintain the weights of prostate and seminal vesicle, whereas levator ani muscle weight was used as a measure of anabolic activity. The maximal response (E(max)) and dose for half-maximal effect (ED(50)) were determined for each compound and compared with that observed for testosterone propionate (TP). Compounds S-1 and S-4 demonstrated in vivo androgenic and anabolic activity, whereas compounds S-2 and S-3 did not. The activities of S-1 and S-4 were tissue-selective in that both compounds stimulated the anabolic organs more than the androgenic organs. These two compounds were less potent and efficacious than TP in androgenic activity, but their anabolic activity was similar to or greater than that of TP. Neither S-1 nor S-4 caused significant luteinizing hormone or follicle stimulating hormone suppression at doses near the ED(50) value. Thus, compounds S-1 and S-4 were identified as SARMs with potent and tissue-selective in vivo pharmacological activity, and represent the first members of a new class of SARMs with selective anabolic effects.
PMID: 12604714 [PubMed - indexed for MEDLINE]
