zman86
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EDIT: I want to thank Hi-tech for selecting me to log their 1-Testosterone, which is 1-Andro utilizing the cyclosome tech. Once I receive the bottles I will link the log here. I also purchased a bottle of OL TheOne to use afterwards to compare effects.
Currently looking for a good Andro product for my pre-contest cut. I was going to go with the OL line Andros but I've read mix reviews.
Here are some that are on the market:
OL's S-SEDD: "Self-emulsifying drug delivery systems (SEDDS). SEDDS have been proven in the last two decades to be a phenomenal success. They are able to overcome some of the biggest challenges confronting contemporary delivery science today by improving on the oral bioavailability of compounds with poor and inconsistent gastrointestinal absorption. SEDDS do so by facilitating absorption of compounds via the intestinal lymphatic system and thus circumnavigating the hepatic first-pass effect. The lymphatic system is a drainage network that extends throughout the entire body in proximity to the circulatory system and is a logical target since orally administered compounds can work more effectively when transported selectively to the intestinal lymphatic system. The bioavailability of compounds that undergo significant first-pass metabolism in the liver, as Andros do without enhanced delivery methods, can be improved dramatically by utilizing the lymphatic system for absorption in the intestine, thus avoiding the destructive first-pass effect in the liver."
Primeval Lab, Black Stone Lab uses Liposomal technology: "Liposomes are sub-microscopic bubbles made from phospholipids. Phospholipids surround every type of cell in the human body. When placed in liquid solutions phospholipids automatically form bubbles that encapsulate the host solution, thus protecting the substance from its surrounding environment. Scientists discovered that these tiny liposomes can be filled with nutrients in order to protect them during digestion and thus allow for increased bioavailability. Phospholipids are resistant to the digestive enzymes found in the gut that would normally be responsible for prematurely breaking down nutrients. They also pass through intestinal barriers with ease due to their small size. Some studies have shown that liposomal encapsulation can increase bioavailability by as much as 1500%."
Hi-Tech Pharma, LG Science uses Cyclosome Delivery: "This one-of-a-kind technology brought to you by the leaders in Prohormones involves the entrapment of hydrophobic prohormones and other Testosterone boosting compounds in the form of water-soluble Prohormone–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to combine the relative advantages of CDs and liposomes into one system, namely Prohormone-in-CD-in-liposome systems called Cyclosome's
. You can think of all this in terms of a ‘Trojan Horse,’ passing through the liver unharmed and intact. As opposed to being destroyed in the liver like all other hormonal products on the market, past and present. This new Cyclosome technology allows the ‘Trojan Horse’ to deliver prohormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. Almost all previous Oral capsules and tablets manufactured to increase testosterone — including Testosterone itself — are involved in the "first pass affect" which renders the active compounds virtually useless."
Any test results and research done on which is the best with the most bio-availability?
Currently looking for a good Andro product for my pre-contest cut. I was going to go with the OL line Andros but I've read mix reviews.
Here are some that are on the market:
OL's S-SEDD: "Self-emulsifying drug delivery systems (SEDDS). SEDDS have been proven in the last two decades to be a phenomenal success. They are able to overcome some of the biggest challenges confronting contemporary delivery science today by improving on the oral bioavailability of compounds with poor and inconsistent gastrointestinal absorption. SEDDS do so by facilitating absorption of compounds via the intestinal lymphatic system and thus circumnavigating the hepatic first-pass effect. The lymphatic system is a drainage network that extends throughout the entire body in proximity to the circulatory system and is a logical target since orally administered compounds can work more effectively when transported selectively to the intestinal lymphatic system. The bioavailability of compounds that undergo significant first-pass metabolism in the liver, as Andros do without enhanced delivery methods, can be improved dramatically by utilizing the lymphatic system for absorption in the intestine, thus avoiding the destructive first-pass effect in the liver."
Primeval Lab, Black Stone Lab uses Liposomal technology: "Liposomes are sub-microscopic bubbles made from phospholipids. Phospholipids surround every type of cell in the human body. When placed in liquid solutions phospholipids automatically form bubbles that encapsulate the host solution, thus protecting the substance from its surrounding environment. Scientists discovered that these tiny liposomes can be filled with nutrients in order to protect them during digestion and thus allow for increased bioavailability. Phospholipids are resistant to the digestive enzymes found in the gut that would normally be responsible for prematurely breaking down nutrients. They also pass through intestinal barriers with ease due to their small size. Some studies have shown that liposomal encapsulation can increase bioavailability by as much as 1500%."
Hi-Tech Pharma, LG Science uses Cyclosome Delivery: "This one-of-a-kind technology brought to you by the leaders in Prohormones involves the entrapment of hydrophobic prohormones and other Testosterone boosting compounds in the form of water-soluble Prohormone–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to combine the relative advantages of CDs and liposomes into one system, namely Prohormone-in-CD-in-liposome systems called Cyclosome's
. You can think of all this in terms of a ‘Trojan Horse,’ passing through the liver unharmed and intact. As opposed to being destroyed in the liver like all other hormonal products on the market, past and present. This new Cyclosome technology allows the ‘Trojan Horse’ to deliver prohormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. Almost all previous Oral capsules and tablets manufactured to increase testosterone — including Testosterone itself — are involved in the "first pass affect" which renders the active compounds virtually useless."Any test results and research done on which is the best with the most bio-availability?
I *really* think we are seeing that the most milligrams for the cheapest price is the way to go - if it happens to include a fancy "system" even better, but price per mg rules the roost.
