new to chemicals trying to learn more

[Affliction2u]

honestly is there much difference between test e and finaflex's 1-andro???

 

[rochabp]

honestly is there much difference between test e and finaflex's 1-andro???

test e is testosterone while 1 andro (1-test) very different...first off all test is king, no arguing that. If you look at the molecular structure test has a double bond at the 4 position while 1 andro, well you guessed it has it at the 1 position

test

1 andro

the double bond is the little dash inside the first hexagon. the 1 position starts at the top of hexagon and goes to 4th position counter clockwise to 4th position at bottom of the 1st hexagon.

the double at the 1 i believe helps it resist liver breakdown

 

[TheProfessor]

The enone is key to binding to the androgen receptor. This is why it's not a "pro" hormone.

Orally active steroids are alkylated at the 17 position to inhibit liver breakdown (ring D)

The "pro" hormone shown needs to be metabolized first, that Alcohol attached to C-3 needs to be oxidized, in order to be relatively active.

the E in Test E has to do with the ester that's attached, a heptanoic acid that has an ester bond to the D ring alcohol on the testosterone molecule. This makes the testosterone "fatty" and therefore accumulates in the tissue and is released over a longer time period.

 

[Affliction2u]

wow i definately didnt realize how different the two compounds really were, thanks for the info guys

 

[Affliction2u]

so i have one more question, is there a way to reduce the attached alcohol without completely changing the supplement itself? say for instance, could you take something else to make it more active.

 

[TheProfessor]

Not a chance. It takes a very strong oxidizing agent to attack that alcohol. And even so, you'd have side reactions that would result in a Dione as well. It would take legitimate chemistry in (relatively) low yields and a large pain in the ass. Don't try it at home

 

[rebelhead]

test e is testosterone while 1 andro (1-test) very different...first off all test is king, no arguing that. If you look at the molecular structure test has a double bond at the 4 position while 1 andro, well you guessed it has it at the 1 position

test
View attachment 45820

1 andro
View attachment 45819

the double bond is the little dash inside the first hexagon. the 1 position starts at the top of hexagon and goes to 4th position counter clockwise to 4th position at bottom of the 1st hexagon.

the double at the 1 i believe helps it resist liver breakdown

the compound shown above is not 1-andro. it is 1-ad.
1-andro is 1-DHEA

3-hydroxy-5 alpha-androst- 1-en-17-one
it will require a 2 step conversion to the active 1-testosterone

 

[rochabp]

the compound shown above is not 1-andro. it is 1-ad.
1-andro is 1-DHEA
View attachment 45847
3-hydroxy-5 alpha-androst- 1-en-17-one
it will require a 2 step conversion to the active 1-testosterone

ur rite

 

[TheProfessor]

the compound shown above is not 1-andro. it is 1-ad.
1-andro is 1-DHEA
View attachment 45847
3-hydroxy-5 alpha-androst- 1-en-17-one
it will require a 2 step conversion to the active 1-testosterone

Good luck with that in your garage in any appreciable yield . Unfortunately any strong oxidizing/reducing agents are notoriously promiscuous and the ones that aren't don't have the greatest yields. I'll leave the chemistry up to my body.:09: