Progesterone and Prolactin
- 04-24-2009, 03:48 PM
wow guys a whole host of info here!
right now i am 4 weeks after a course of superdrol and it has cause some gyno, now i have been all over the boards and came to the conclusion that i need to do get hold of cabaser (carbogoline) to supress my prolactin levels... i have done this but with no effect!
i currently have cabaser and nolva on hand and i was scared to use the nolva as it was considered bad for this type of gyno.
now from what i have read it would be best for me to run a low dose of nolva for an extended period of time so that my SHBG levels would be up after a while... my question is if i took cabaser at the same time would this have me coverd or surpress my SHGB
i want to bring up letro as a hot potato here and what role that would play as iv not seen it mentioned yet....
from all the boards i have read it seems this is the most knowledgeable and i woud greatly respect your opinion on this matter thanks lee
- 04-24-2009, 06:52 PM
Now, I will say that a qualified opinion always carries more weight than an unqualified one (that is why they have experts testify in court) but good ideas can come from anywhere. It is easy from me. I can stay here and state my theories and answer questions or I can not. My expertise is recognized outside of these boards. The difficult part is for the guys looking for answers because they have to weed through the bullsh-t and make a determination as to who is believable and what is a good idea.
- 04-24-2009, 06:55 PM
04-24-2009, 07:02 PM
04-24-2009, 07:13 PM
04-24-2009, 07:23 PM
04-24-2009, 07:26 PM
Great thread and thanks for taking the time to do this. Maybe post this at bb.com. I post there the most, but there are ALOT of questions in regards to prolactin, progesterone, gyno and so forth.
04-24-2009, 08:26 PM
04-24-2009, 08:40 PM
There is also some potential for cardiac valvulopathy but that is generally with longer term use.
The larger concern is not even listed as a potential side effect. In the lab we used dopamine agonists to desensitize dopamine receptors. We did it to mimic parkinson's and though i doubt that is a concern here, the desensitization is a concern because the loss of dopaminergic suppression of lactotropes could actually result in prolactin excess.
04-25-2009, 05:02 PM
04-26-2009, 08:07 AM
04-26-2009, 12:16 PM
04-26-2009, 12:49 PM
04-26-2009, 03:39 PM
seth, eric: what are your views on Bromocriptine in the event of prolactin problems? will it be effective against 1-t tren gyno? (if any occurs) im also confused about its long term effects, will there be any effects of a short 1.25mg ED sort of course if I needed it to cure issues on/after 1-t tren? Do either of you also have views on running it on cycle, or is it just overkill?
04-26-2009, 04:11 PM
I’d appreciate it if you could touch on the anadrol-winstrol relationship. It’s got me a little confused.
Anadrol doesn’t aromatize obviously… Historically its sides have been attributed to progestins, as it binds PR but not AR. Now, you’ve stated that the release of bound estrogens due to lowered SHBG levels, as well as the loss of the general protective effects of SHBG can explain gyno with certain compounds such as SD, phera, anadrol and tren. That makes sense to me so far.
Running winny alongside anadrol seems to cut down on sides. Yet winny supposedly knocks down SHBG levels greatly. It’s also been said that winny has “anti-progestagenic” effects. I don’t know what that really entails. If anadrol’s sides are indeed due to freed estrogen and a lowered SHBG environment, can you explain what happens when winny is added to the model? Why aren't anadrol's sides more pronounced? TIA.
04-26-2009, 06:26 PM
04-26-2009, 06:32 PM
04-26-2009, 06:35 PM
04-26-2009, 06:41 PM
04-26-2009, 06:52 PM
04-26-2009, 07:13 PM
04-26-2009, 07:36 PM
04-26-2009, 07:45 PM
04-26-2009, 07:51 PM
Damn - It looks like a missed quite a bit in the week i was gone. I have some catching up to do with reading.
I have some good endocrine/pathophysiology info to add to this discussion.
Evolutionary Muse - Inspire to Evolve
04-26-2009, 08:16 PM
04-26-2009, 08:17 PM
04-28-2009, 01:27 PM
What to do on cycle and PCT for Tren? I can firmly agree with you on the matter of controlling estrogen to avoid gyno of any type, but you don't recommend the use of AI's, even the weaker ones, while on cycle. Why? I thought AI's did just that -- control estrogen levels. And yes, I heard about the whole idea of Tren shutting you down and making the body "vulnerable" to "free" estrogen, which is suspect to cause all this gyno in the first place. AI's don't have any affect on free estro?
I would almost think a reasonable dose of AI while on cycle would work just fine. That is what I'm currently doing, and so far no problems have arised. Of course, I'm using Formex, which is formestane. The me and thebigT are the current people using Tren and formestane, although he is using the transdermal form, I am not.
But the real question for myself is how to come off the AI once the cycle is over. Cold turkey sounds like a recipe for estrogen spikes to me. What would you recommend?
04-28-2009, 02:34 PM
The theory makes sense, but I would still caution against the SERM administration and instead opt for prolactin control. (Being a potent co-factor in breast growth, perhaps keeping it in the sub-physiological range will partly cripple estrogens ability to induce mammary growth)
04-28-2009, 02:35 PM
04-28-2009, 04:41 PM
and I might consider buying the Vitrix stuff, since I've heard good results in libido enhancements, or I might opt for Hydrotest. So if anyone on here has experience with the same or similar PCT please chime in on how to use them together in regards to Tren or Trenlike PH's. Thanks.
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