4OHN is not suppressive

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  1. 4OH is not suppressive


    My ass. I've been on VPX 4-OH for only one week and my sex drive is dead and I couldn't cum tonight when I had sex, I think its worse then 1-AD.
    Last edited by badbart; 11-11-2003 at 01:53 PM.


  2. From my experience with anabolics, everything is suppressive.
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  3. I think 4-OH surpression comes on much faster and harder then test. One freaking week and my nuts are small and my sex drive is gone. 4-AD didn't shrink the nuts this bad after 2 weeks. Other then this it seems to be quit effective at bulding muscle.

  4. Well... it seems to be a compound somewhat similar to decca, which is infamous for shutting your sex drive down and shrinking your nuts.

    ManBeast
    -Saving random peoples' nuts, one pair at at time... PCT info:
    http://anabolicminds.com/forum/steroids/192992-pct-what-why.html
    -Are you really ready for a cycle? Read this link and be honest:
    http://anabolicminds.com/forum/steroids/191120-checklist-before-thinking.html
    *I am not a medical expert, my opinions are not professional, and I strongly suggest doing research of your own.*

  5. That sucks, I was thinking of stacking 4OHT with m-1-t which happens to be a potent ball shrinker as well.
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  6. I would not rely on "nut shrinkage" as a true measure of HPTA suppression.

  7. Whoever said 4-OHT isn't suppressive?

    Effects of 4-hydroxyandrost-4-ene-3,17-dione and its metabolites on 5 alpha-reductase activity and the androgen receptor.

    Davies JH, Shearer RJ, Rowlands MG, Poon GK, Houghton J, Jarman M, Dowsett M.

    Department of Urology, St. Georges Hospital, London, England, UK.

    The steroidal aromatase inhibitor, 4-hydroxyandrost-4-ene-3,17-dione (4OHA) and its metabolites, 4-hydroxytestosterone (4OHT), 3 beta,17-dihydroxy-5 alpha-androstan-4-one (metabolite A) and 3 alpha, 17-dihydroxy-5 beta-androstan-4-one (metabolite B) were evaluated as inhibitors of the human prostatic 5 alpha-reductase enzyme and for binding to the rat prostatic androgen receptor. 4OHA and 4OHT were weak inhibitors of 5 alpha-reductase with IC50 values of 15-29 microM. Metabolites A and B had no significant inhibitory activity. 4OHA and metabolites A and B bound weakly to the androgen receptor. The binding affinities (RBA) relative to mibolerone (RBA = 100) were 0.085, 0.485 and 0.016, respectively. However, 4OHT (RBA = 75) was a more potent binder than the endogenous androgen 5 alpha-dihydrotestosterone (RBA = 66). ability of these metabolites, in particular 4OHT, to bind to the androgen receptor explain the in vivo androgenic activity of 4OHA.
    For answers to board issues, read the Suggestion and News forum at the bottom of the main page.

  8. Just out of curiosity, are you injecting? I assume that you are. If so, how much and what kind of results are you seeing? I wanna try this stuff out, but am waiting on other suppliers to come out with this product. thanks

  9. Good **** bobo, you da man!

    ManBeast
    -Saving random peoples' nuts, one pair at at time... PCT info:
    http://anabolicminds.com/forum/steroids/192992-pct-what-why.html
    -Are you really ready for a cycle? Read this link and be honest:
    http://anabolicminds.com/forum/steroids/191120-checklist-before-thinking.html
    *I am not a medical expert, my opinions are not professional, and I strongly suggest doing research of your own.*

  10. Oral not injecting. I've read a couple other post that were asking if 4OHN was surpressive.

  11. Ummm... VPX hasn't released their OHN yet. Only the OHT.

  12. Woops I meant OHT.

  13. Nothing better than some suppressive-ass androgens to make you a marathon man. It's a dead giveaway to my old lady when I'm on, 'cause she walks around with sore jaws! LOL!

  14. I was really surprised suppression happened in such a short time. The stuff works but its also a sex drive killer. I used it once before but it was with 4-AD and I didnít notice the lack of sex drive. I also seem to shut down faster then most people I notice suppression on 4-ad after only one and a half weeks, not total shut down but noticeable lack of sex drive when I quit for about one week.

  15. Are you taking any liquid PCT? Let us know if it helps.

  16. Are you taking any liquid PCT? Let us know if it helps.

    No, I was only on it a week. I already feel a little better but it has taken 5 days after only 7 days on. I wanted to do a 3 to 4 week cycle but this has sort of scared me away from doing that. Iím not worried about recovery I was surprised how fast suppression happened.

  17. Did you take a long(enough) time off before your current cycle? Maybe you weren't fully recovered yet.

  18. I haven't done a cycle in months.

  19. Fast shutdown does not mean that recovery will be difficult, and less than a week to return to normal after being shutdown for an entire week without the use of PCT is nothing to complain about.

    ManBeast
    -Saving random peoples' nuts, one pair at at time... PCT info:
    http://anabolicminds.com/forum/steroids/192992-pct-what-why.html
    -Are you really ready for a cycle? Read this link and be honest:
    http://anabolicminds.com/forum/steroids/191120-checklist-before-thinking.html
    *I am not a medical expert, my opinions are not professional, and I strongly suggest doing research of your own.*

  20. all AAS are going to be suppressive to some degree, but what I have found is that 4-OHT and some metabolites stimulate LH to a small degree. Nothing to be noted of though, just blown out of proportion by VPX.

  21. I actually have a study that show D-bol raises LH within the first week. After that we all know what happens. Its just another way to exploit a study by giving you only partial inforamtion.
    For answers to board issues, read the Suggestion and News forum at the bottom of the main page.

  22. It wasn't meant to be a complaint just an observation. I never seem to have a hard time recovering. I think the stuff works well next time I need to add a little 4-AD. I've been looking for an alterative to 1-Test/1-Ad and 4-Ad because 4-AD seems to attack my prostate and 1-Test seems to kill my immune system. If its either a swelled prostate and or dead immune or no sex drive I'll take no sex drive any day.

    Anyone make 4-OH in an inject able version. I know VPX is suppose to be but it seems thick and I've heard painful stories about it.
    .

  23. Exactly, kind of what VPX does best.... but they feel no need to cite the study either...

  24. P.S. I was a little drunk when I first posted this.

  25. You seem to have the same response to 4AD that I do BAD.

    After just a week I was almost completely shut down. Prostate and testicles were enlarged and tingling a lot. A short course of saw palmetto seemed to clear this up although it could have just been my body adapting to the higher androgen level on its own.

  26. Originally posted by nsruffryder34
    Exactly, kind of what VPX does best.... but they feel no need to cite the study either...
    Do you know were I can get injectable 4-OH?

  27. I think instynct has it, animal has it, and sledgehammer shuld have it soon. I would wait for sledge to have it, he is the cheapest.

  28. Originally posted by bioman
    You seem to have the same response to 4AD that I do BAD.

    After just a week I was almost completely shut down. Prostate and testicles were enlarged and tingling a lot. A short course of saw palmetto seemed to clear this up although it could have just been my body adapting to the higher androgen level on its own.
    Yep, if I use it again I'm going to use a very small dose. I Amazes me how bad the stuff kills me. I've tried everything to see if I can combat the sides but nothing helped for very long. Iíve tried saw palmetto, pumpkin seeds, finaside and nolva nothing worked for very long. But Iíve never tried finaside and nolva together I wonder if that would do the trick? But now when I've tried it I can feel my balls hurting after only a couple days. I also wonder if its more of an inflammation of my plumbing below rather them my prostate enlarging since it happens so fast.

  29. Originally posted by nsruffryder34
    I think instynct has it, animal has it, and sledgehammer shuld have it soon. I would wait for sledge to have it, he is the cheapest.
    Whats sledgehammer's wed address.

  30. Im not sure if he has one yet, Ill talk to him later and get back to you as soon as I do...
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