Bulk Berberine

[dsade]

A supplier has some overstock of Berberine that he is going to sell to us at a discount. We should be able to put together a VERY kickass SesaThin/DCP/Berberine stack for the holidays.

 

[johnfaceman]

Damn D, how am I suppose to order the whole stock if you go advertising it. Keep us updated brotha!:cheers:

 

[jdev]

what products is berberine in? or what does it do?

 

[scott72]

what products is berberine in? or what does it do?

http://anabolicminds.com/forum/supplement-articles/50900-berberine-aids-insulin.html?highlight=Berberine

 

[johnfaceman]

I know it is in Alri Lean Dreams.

 

[Jayhawkk]

Berberine seems to be the 'in' topic at the moment

 

[johnfaceman]

Berberine seems to be the 'in' topic at the moment

Yea just saw what you are talking about :head:

 

[Rodja]

What is DCP?

 

[WannaBeHulk]

What is DCP?

i think its dsades capped concoction that nutra will be carrying standing for Damage Control Protocol. very good idea IMO

 

[Rodja]

i think its dsades capped concoction that nutra will be carrying standing for Damage Control Protocol. very good idea IMO

That would make sense. I think that if you don't lose weight on that stack, then there needs to be a scientific study on their metabolism.

 

[WhatsaRoid?]

Lets be real man, how does that bulk Berberine compare to AP? I jus want the bulk Berberine to add to everything else I have I don't need the stack. how soon will Berberine be up for purchase?

 

[WannaBeHulk]

That would make sense. I think that if you don't lose weight on that stack, then there needs to be a scientific study on their metabolism.

very true but i think it will be marketed to use when the diet is subpar or slacking... i.e. the holiday season, on vacation, or the infamous cheats. i would like it for contest prep myself

 

[Rodja]

very true but i think it will be marketed to use when the diet is subpar or slacking... i.e. the holiday season, on vacation, or the infamous cheats. i would like it for contest prep myself

I want to try before I have to cut weight. I know that I would probably have to stop the TTA usage about 2 wks before weigh-in for water retention, but I can only imagine how potent this stack is, especially if you stack some LX with it.

 

[I-Vtec]

is this similiar to Yellow gold?

how is this dosed?

sign me up for a few pounds

 

[prld2gr8ns]

is this similiar to Yellow gold?

how is this dosed?

sign me up for a few pounds

Similiar in that it's a percentage of the whole, have no idea how ithwould be dosed though, but my guess would be in much larger quanities then AP.

 

[dsade]

I would say 100-200mg would be POTENT.

This shipped out today, and should be on the site by Thursday.

 

[prld2gr8ns]

Perhaps large was an overstatement.

 

[dsade]

Pricing should be somewhere near the following:

25 grams: $9.95, 50 grams $15

 

[scott72]

I would say 100-200mg would be POTENT.

This shipped out today, and should be on the site by Thursday.

How many doses a day would be optimal?

 

[dsade]

It looks to be a tradoff between possible detrimental effects on hypertrophy, and AMPk activation.

Still looking into it more.

 

[WhatsaRoid?]

I would say 100-200mg would be POTENT.

This shipped out today, and should be on the site by Thursday.

You are the man...hell yea I been waiting all this time for my god damn ap so I can place a order. **** it ima buy this..dsade did it again.

 

[P01Shooter]

Pricing should be somewhere near the following:

25 grams: $9.95, 50 grams $15

Have you guys thought about volume discounts? There are several herbs I'd be willing to get a kilo or 500 g's if it was worth it.

 

[johnfaceman]

Have you guys thought about volume discounts? There are several herbs I'd be willing to get a kilo or 500 g's if it was worth it.

Im with you on that one brotha. or at least like 200 grams :hot:

 

[freezito]

whats the dosing on this stuff

 

[warnerve]

^^^^^^^^

I would say 100-200mg would be POTENT.

 

[Mulletsoldier]

I do not wish to cause any controversy or argument so I will make this brief. Bulk Berberine is not Anabolic Pump, Phellodendron contains Berberine, though our extract does not utilize AMPK activation, and does not pose a detriment to protein synthesis

-Mullet

 

[johnfaceman]

I do not wish to cause any controversy or argument so I will make this brief. Bulk Berberine is not Anabolic Pump, Phellodendron contains Berberine, though our extract does not utilize AMPK activation, and does not pose a detriment to protein synthesis

-Mullet

No controversy here :drunk: . I just want this to hold me till AP arrives. If it works well I may use it in conjunction with a lower dose of AP to alleviate the cost.

 

[WhatsaRoid?]

No controversy here :drunk: . I just want this to hold me till AP arrives. If it works well I may use it in conjunction with a lower dose of AP to alleviate the cost.

i feel the same way...

 

[scott72]

^^^^^^^^

A day or several times a day??

 

[warnerve]

My guess would be around 3 times a day a little bit before a meal, similar to yellow gold. I could be wrong though, I would wait for dsade for the final word

 

[dsade]

FYI...Nobody claimed that this was Anabolic Pump.

 

[wojo]

FYI...Nobody claimed that this was Anabolic Pump.

i was wondering about that.seems nutra and usplabs have a very good relationship and i know in previous post you have said that you didnt wanna try to copy there formulations.theres a lot of assumptions being made by people tho

 

[dsade]

i was wondering about that.seems nutra and usplabs have a very good relationship and i know in previous post you have said that you didnt wanna try to copy there formulations.theres a lot of assumptions being made by people tho

Berberine was requested as something that would stack well with DCP.

I also went over my supplier's overstock list, and he had it for me.

As for the jabs being thrown our way that we are aching to copy USP...ridiculous. I can do my own research and design, as I have already proven.

 

[johnfaceman]

Berberine was requested as something that would stack well with DCP.

I also went over my supplier's overstock list, and he had it for me.

As for the jabs being thrown our way that we are aching to copy USP...ridiculous. I can do my own research and design, as I have already proven.

Yea... I think you reaking HAVOC, and the beauty of DCP will prove that. Anyway AP is being reformulated for any of those thinking it will be a copy.

 

[dsade]

Derived from the Vinegar discussion at M&M, and the article cited:

Cellular Basis of Exercise-induced Changes in Substrate Metabolism
Finally, Neil Ruderman, MD, PhD, of the Boston University School of Medicine, a leader in the enzymology of muscle metabolic pathways, discussed the latest information on the cellular basis for exercise-induced changes in substrate metabolism.[7] Dr. Ruderman addressed the regulatory events that allow the muscle cell to utilize glucose or fatty acids at rest and during exercise, and he focused particularly on the role of AMP-activated protein kinase (AMPK) in fatty acid oxidation.
Skeletal muscles consume 80% to 90% of whole body oxygen utilized during exercise. Their choice of substrate for fuel differs during rest and exercise in normal persons. At rest (while fasting) about 90% of fuel consumption is fatty acid-derived and about 10% is carbohydrate-derived. But with moderate exercise, there are substantial increases in both fatty acid and carbohydrate oxidation. How do these shifts occur? There is an important molecular sensor that regulates the change the level of AMP in the cell, which reflects a decrease in the fuel supply.

During exercise, as a result of increased glucose uptake and glycogenolysis, glucose-6-phosphate increases in muscle cells. Normally it is not permitted to accumulate because pyruvate dehydrogenase is activated within seconds, resulting in increased flux through the Krebs cycle leading to increased glucose oxidation. Fatty acids are likewise oxidized but via a different pathway under different regulation. Lipolysis during exercise leads to increased delivery of free fatty acids to muscle cells. These are taken up by the cells, initially bound to a fatty acid binding protein, and then acted on by fatty acyl-CoA synthase to produce long chain fatty acyl-CoA.

A crucial next step is the activation of carnitine palmitoyl transferase I (CPT I) to shuttle the fatty acyl-CoA into the mitochondria for oxidation. CPT I is inhibited by malonyl-CoA, which is synthesized by the action of acetyl-CoA carboxylase (ACC), ACC is regulated positively by increased citrate (an allosteric activator that accumulates in the presence of insulin and glucose) and negatively by AMPK. Citrate activates ACC, while AMPK phosphorylates and inhibits ACC in a manner that supersedes the effect of insulin and glucose. A third regulator of malonyl-CoA is malonyl-CoA decarboxylase, the activity of which is also increased by AMPK, and which decreases malonyl-CoA levels in the cytosol.

To put these events in a physiologic context: during feeding, in the presence of insulin and glucose, malonyl-CoA accumulates and inhibits CPT I, thus inhibiting fatty acid oxidation. Conversely, when the muscle cell is deprived of glucose, or when it is contracting, malonyl-CoA decreases due to increased AMPK activity (resulting from low fuel supply and increased cellular AMP) as well as increased malonyl-CoA decarboxylase activity -- fatty acyl-CoA can then be transferred to the mitochondrion for oxidation.

So, as a result of AMPK activation during muscle contraction, the activity of ACC goes down and the activity of malonyl-CoA decarboxylase goes up, and they remain in this state for some time after the contraction. During this time the concentration of malonyl-CoA presumably remains low, permitting enhanced fatty acid oxidation. This mechanism may be a major pathway of enhancing lipid oxidation after exercise. There are also other amplifying effects of this mechanism. For instance, AMPK can also phosphorylate and inhibit glycerol phosphate acyl-transferase, an early step in forming diacylglycerol and triglycerides. It would be beneficial to prevent the accumulation of these lipid moieties in the muscle cell, inasmuch as increases in muscle diacylglycerol, triglyceride, fatty acyl-CoA, and the resultant activation of protein kinase C isoforms, are associated with insulin resistance. Furthermore, data from research by Goodyear and colleagues[8] at the Joslin Diabetes Center, Boston, show AMPK activity enhances glucose uptake into muscle cells.[8]

These data underscore the importance of effective lipid oxidation in response


taken from:Log In Problems

Correct me, then, if I am wrong...but a DCP/SesaThin/Berberine dose before workout, then Anti-Oxidants/HCA/Vinegar/citrate post workout would seem to be an extremely potent Recomp protocol?

Thoughts?

 

[johnfaceman]

Not the smartest person here, but it sounds pretty damn spot on to me. I might give it a run when I can buy some DCP samples and let you know.

 

[wojo]

yea im hoping dcp becomes available soon

 

[dsade]

yea im hoping dcp becomes available soon

I'll have the firm date for you guys today.

 

[stryder]

I love the addition of RK in the formula...read a very good write up on the benefits for fat loss over at BB.com

This design will truly change the direction of fat loss supplements in the industry!

 

[Max32]

interesting.....

 

[johnfaceman]

Whats the good news?!? :blink:

 

[johnfaceman]

Whats the good news?!? :blink:

Bump, was hoping to make an order soon.

 

[Jayhawkk]

Sorry guys I bought it all up... Please move along.

 

[johnfaceman]

Sorry guys I bought it all up... Please move along.

Now we all know thats not true. D was told to hold a couple kilos for me :twisted:

 

[dsade]

There was a miscalculation on the total amount he had on hand. There is only going to be a little bit available. I did, however, talk to my overseas source to bring in more material.

The price wont be beat by anyone.

 

[johnfaceman]

There was a miscalculation on the total amount he had on hand. There is only going to be a little bit available. I did, however, talk to my overseas source to bring in more material.

The price wont be beat by anyone.

When will you have that little bit available. Im ready to buy.

 

[dsade]

When will you have that little bit available. Im ready to buy.

Monday.

 

[Jayhawkk]

2 days to steal the ATM on the corner...check.

 

[stryder]

Bulk Berberine HCL now in stock

 

[johnfaceman]

Bulk Berberine HCL now in stock

Got some coming my way! :bb2: