- 09-02-2012, 09:32 PM
- 09-02-2012, 09:48 PM
- 09-06-2012, 02:26 AM
09-06-2012, 01:57 PM
09-07-2012, 06:31 PM
09-09-2012, 01:35 AM
09-10-2012, 01:17 PM
I picked up some of the liver lock, same stuff.
Rejoice not against me, O mine enemy: when I fall, I shall arise; when I sit in darkness, the LORD shall be a light unto me. Micah 7:8
09-10-2012, 01:23 PM
Yup looks like liver lock is back in stock.
10-06-2012, 12:26 PM
NP needs to give us the option to select USPS for the package handler. I hate FedEx with a burning passion.
10-06-2012, 12:30 PM
10-06-2012, 12:58 PM
Hell I've ordered stuff from Canada that was handled from Canada and domestically through USPS and still received it in 5 days (ordered on Monday morning, received Friday mid-afternoon of the same week).
FedEx is just.. slow as balls. Always has been with my packages =\
10-06-2012, 02:07 PM
I still have yet to have an issue with FedEx. UPS on the other hand is a different story. I've had everything from delivering to the wrong address to the train carrying my package derailing.
M.Ed. Ex Phys
10-06-2012, 06:06 PM
10-07-2012, 11:55 AM
10-09-2012, 01:29 AM
05-19-2013, 08:37 PM
05-21-2013, 11:57 PM
05-22-2013, 01:09 AM
I'd have to read more, but this product isn't making sense to me. TUDCA is a metabolite of UDCA. Okay, sweet... we see UDCA used clinically for cholesterol gallstones, which makes sense given it's a bile acid. WE also see it in patients with primary sclerosing cholangitis But, it seems like people are taking it because it reduces AST/ALT. However, that's in patients with primary sclerosing cholangitis, which narrows the bile tree meaning that heavy bile production could easily lead to cholestasis, a mechanism by which people with PSC see development of transaminitis (elevated AST/ALT). You'll also notice that although it's reducing an improvement in liver chemistry in patients with PSC, it didn't reduce their mortality or incidence of liver transplantation because all it's doing is addressing the cholestasis aspect of PSC, not the underlying histopathological changes that lead to fulminant hepatic failure. It seems a fair extrapolation to say that if you don't have some form of cholestasis, you shouldn't be expecting too much assistance from TUDCA/UDCA because that's not the primary mechanism by which steroid users are experiencing a transaminitis. We call it "chemical hepatitis" for a reason--the chemical is having a direct effect on the liver's parenchyma.
All I'm seeing here is that, unless you've got confirmed cholesterol gallstones or are unfortunate enough to have symptomatic primary sclerosiing cholangitis, you're supplementing with an expensive product that probably won't do anything to help you combat steroid-induced hepatitis.
NAC on the other hand augments glutathione reserves in the body, which is a powerful anti-oxidant and plays a direct role in detoxification. So, it's supplementation makes a whole lot more sense empirically.
But hey, that's just my .02.
"I'm not fat, I'm big boned!"
05-22-2013, 05:13 AM
But you know the fear factor shrouding orals still runs rampant 'round these here parts. Fear kept alive by the occasional hepatic horror story of some guy exploding at the gym from biliary obstruction. It's almost achieved an urban legend status at this point...... "and just then as we were all sitting around the campfire, this crazed killer wearing a hockey mask ran up to us from out of the woods, holding a bloody bottle of dbol in his hideous cholecystitic hands! Take your TUDCA and Milk Thistle cuz he's probably coming for you too... Ahhhh!!!!"
05-22-2013, 09:20 AM
Good discussion and all, but the one time I ran UDCA is also the one time I had outstanding CBC results just two days after the cycle. But milk thistle isn't all that effective. It takes a lot of it to actually make a difference, which still winds up being marginal. It seems to me that the best approach is to limit the cycle of orals with plenty of time off in between cycles and avoiding alcohol in general. Between those two you can remain in a safe stance against liver problems.
If you just wanted to lower cholesterol levels there are a host of other options out there that can easily do that...
05-24-2013, 09:10 AM
05-24-2013, 09:10 AM
05-27-2013, 07:56 AM
05-28-2013, 06:08 PM
05-28-2013, 06:08 PM
05-29-2013, 07:07 AM
05-30-2013, 12:09 AM
05-30-2013, 08:31 AM
05-31-2013, 02:25 AM
05-31-2013, 02:20 PM
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