T-Rez has arrived! Hear it roar!
- 08-28-2008, 06:57 PM
- 08-28-2008, 07:07 PM
08-28-2008, 07:09 PM
I know piperine exerts it's effects for several hours after taking it, so ideally one would take something with piperine then either soon after or at most an hour or two after take the resveratrol.
No idea about quercetin though, i imagine it follows a similar pattern so you'd be best dosing within a short time frame.
08-28-2008, 08:05 PM
Some info you guys may enjoy
De Santi et al. Xenobiotica 30, 609-617 (2000).
Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum
1. Resveratrol, a polyphenolic compound present in grapes and wine, has beneficial effects against cancer and protective effects on the cardiovascular system. It is present in the diet, and the hepatic and duodenal sulphation might limit the bioavailability of this compound. The aim was to study the sulphation of resveratrol in the human liver and duodenum. 2. A simple and reproducible radiometric assay for resveratrol sulphation was developed. It employed 3'-phosphoadenosine-5'-phosphosulphate-[S-35] as the sulphate donor and the rates of resveratrol sulphation (mean +/- SD, pmol/min/mg cytosolic protein) were 90+/-21 (liver, n = 10) and 74+/-60 (duodenum, n = 10, P = 0.082).3. Resveratrol sulphotransferase followed Michaelis-Menten kinetics and K-m, (mean+/-SD; mu M) was 0.63=/-0.03 (liver, n = 5) and 0.50+/-0.26 (duodenum, n = 5, p = 0.39) and V-max (mean+/-SD, pmol/min/mg cytosolic protein) were 125+/-31 (liver, n = 5) and 129+85 (duodenum, n = 5, p = 0.62).4. Resveratrol sulphation was inhibited by the flavonoid quercetin, by mefenamic acid and salicylic acid, two commonly used non-steroidal anti-inflammatory drugs. IC50 of resveratrol sulphation for quercetin was 12+/-2 pM (liver) and 15+/-2 pM (duodenum), those for mefenamic acid were 24+/-3 nM (liver) and 11+/-0.6 nM (duodenum), and those for salicylic acid were 53+/-9 mu M (liver) and 66+/-4 mu M (duodenum).5. The potent inhibition of resveratrol sulphation by quercetin, a flavonoid present in wine, fruits and vegetables, suggests that compounds present in the diet may inhibit the sulphation of resveratrol, thus improving its bioavailability.
09-05-2008, 05:14 PM
09-05-2008, 05:47 PM
09-06-2008, 01:47 PM
09-06-2008, 04:34 PM
09-06-2008, 05:35 PM
Ive seen a bunch of products only giving around 1,200 mg at 50% or around 600 mg a day comparable
Is 1,200 mg a day really needed .. even dosed at 2x a day its still 800 mg vs other companies 600 mg.
09-12-2008, 01:17 PM
no, it's not necessary to dose res-v that high.
for general helth benefits a lower dose would suffice and allow your product to last longer.
however, the studies showing an improvement in enhancing testesterone production were using higher dosages.
09-12-2008, 04:04 PM
Just thinking out loud here, but now that we've reduced the T-Rez to 60 caps of 400mg 98% trans-resveratrol with piperine. Would anybody be interested in 120 caps with half the dose, so say 200mg? This might help spread it out more evenly over the day, not positive what the jump in cost would be but 60 gel caps isn't very much, and the bottle already fit 120 caps.
09-12-2008, 06:16 PM
09-15-2008, 04:52 AM
09-15-2008, 05:34 AM
09-15-2008, 08:36 AM
09-15-2008, 05:51 PM
09-15-2008, 06:35 PM
09-16-2008, 09:58 AM
09-16-2008, 04:51 PM
09-16-2008, 07:38 PM
http://www.nutraplanet.com/product/n...-capsules.html (Capped OOS, can get bulk http://www.nutraplanet.com/product/n...-50-grams.html ). That way you can use more of the T that dermacrine gives you.
09-16-2008, 09:34 PM
09-21-2008, 05:18 PM
10-04-2008, 04:46 PM
10-04-2008, 06:22 PM
Slight delay because I think we went ahead and added the Piperine. Pushed it back a bit, but should be shipped to us this coming week.
10-04-2008, 09:23 PM
10-14-2008, 08:46 PM
so is there a way i can just pay for the t-rez nd you guys send it too me when i get it because i want to make a big order and im waiting on the t-rez?
10-14-2008, 09:30 PM
10-14-2008, 09:39 PM
Combination of Lipids and Emulsifiers Enhances the Absorption of Orally Administered Quercetin in Rats
Ethanol is not helpful for the effective absorption of quercetin, as a high concentration is required. In conclusion, a combination of lipids and emulsifiers is necessary for enhancing quercetin absorption.
10-15-2008, 07:03 AM
10-21-2008, 10:23 PM
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