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My take on IGF-1

  1.  03-19-2011  12:40 AM
    Registered User boosted5038's Avatar
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    does anyone know why grunt76 fell off the radar??



  2.  03-23-2011  12:46 AM
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    Hey guys, I am suffering from a rare stomach condition, and I saw that on the net you folks have the most information. I am actually looking into IGF-1 DES 1 3 as a therapeutic agent, and I was wondering about the following:

    1.) can it be injected subcutaneously for any effect?
    2.) Will the effect be local or systemic, if so?
    3.) What is the ideal manner of reconstitution for IGF DES 1 3?

    I know it's all experimental, but I want to give it a shot because nothing else has been working. I read IGF DES 1 3 stimulates gut cell proliferation, and also aids in nutrient uptake. Beyond that, I heard IGF helps protect the pathways responsible for gastrointestinal motility, which is a problem I am having.

    Any information would be hugely appreciated.

    Thank you.

  3.  05-22-2011  04:46 AM
    Registered User Ivan Valdez's Avatar
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    you can purchase all teh Naci in Ukraine that you want. just walk into the pharmacy and buy it

  4.  05-22-2011  04:47 AM
    Registered User Ivan Valdez's Avatar
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    you can purchase all the Naci in Ukraine that you want. just walk into the pharmacy and buy it

  5.  06-13-2011  01:57 PM
    Registered User stankyleg's Avatar
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    Originally Posted by HealthMystery View Post
    1.) can it be injected subcutaneously for any effect?
    Bump it yo

  6.  06-24-2011  08:40 PM
    Registered User Grunt7684's Avatar
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    Originally Posted by boosted5038 View Post
    does anyone know why grunt76 fell off the radar??
    I'm still around, kinda. I'm sick right now with extreme adrenal burnout and a concomitant metabolic disease, so I am mostly bedridden and most certainly cannot workout. So I am much less present on forums. But I hope to have all this fixed within a couple years and come back to my good ole habits.

    I am using this handle because my old Grunt76 handle got hijacked by a pirate/hacker some time back.

  7.  06-24-2011  08:41 PM
    Registered User Grunt7684's Avatar
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    Originally Posted by Patrick Arnold View Post
    potentially

    it cant hurt
    I'm pretty sure it has been demonstrated that ligaments don't have any IGF receptors, but that they do have GH receptors...

  8.  06-25-2011  06:07 AM
    Registered User RedwolfWV's Avatar
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    [QUOTE=Grunt7684;2916581]I'm still around, kinda. I'm sick right now with extreme adrenal burnout and a concomitant metabolic disease, so I am mostly bedridden and most certainly cannot workout. So I am much less present on forums. But I hope to have all this fixed within !

    Damn Grunt, get well soon.. We need ya here!

  9.  07-31-2011  10:59 PM
    Registered User stankyleg's Avatar
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    Any idea what caused ur contam disease? Hate to hear it bro
    Everything I say is fictional and for entertainment purposes only.

  10.  07-31-2011  11:23 PM
    Registered User Blergs's Avatar
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    " It means that technically, for the part of the muscle in which you inject, THERE IS NO DIFFERENCE BETWEEN rhIGF-1 and Long R3 IGF-1. They both have the EXACT SAME LOCAL EFFECT. But rhIGF-1 gets neutralized quick, whereas Long R3 gets to float around until it finds a receptor."

    THANKYOU!!!! :-)
    LG Sciences Board Rep
    These statements have not been evaluated by the FDA, do not constitute medical advice, and are not official or authorized comments by LG Sciences, LLC.

  11.  07-31-2011  11:24 PM
    Registered User Blergs's Avatar
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    I LOVE igf1LR3 myself I like it at 40-80mcg ed (and YES I NOTICE MORE FROM 70-80MCG ed then only 40! and yes its worth it) but i mostly stick to 40-50mcg for abotu 8 wks at a time
    LG Sciences Board Rep
    These statements have not been evaluated by the FDA, do not constitute medical advice, and are not official or authorized comments by LG Sciences, LLC.

  12.  07-31-2011  11:27 PM
    Registered User Blergs's Avatar
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    Originally Posted by HealthMystery View Post
    Hey guys, I am suffering from a rare stomach condition, and I saw that on the net you folks have the most information. I am actually looking into IGF-1 DES 1 3 as a therapeutic agent, and I was wondering about the following:

    1.) can it be injected subcutaneously for any effect?
    2.) Will the effect be local or systemic, if so?
    3.) What is the ideal manner of reconstitution for IGF DES 1 3?

    I know it's all experimental, but I want to give it a shot because nothing else has been working. I read IGF DES 1 3 stimulates gut cell proliferation, and also aids in nutrient uptake. Beyond that, I heard IGF helps protect the pathways responsible for gastrointestinal motility, which is a problem I am having.

    Any information would be hugely appreciated.

    Thank you.
    1) YES of course it can thats the only way iv been usign ti with great results
    1) all igf1 or igf1lr3 go's systemic but igf1 gets cleared out fast in minutes and igf1lr3 is like 20hrs
    3) google
    LG Sciences Board Rep
    These statements have not been evaluated by the FDA, do not constitute medical advice, and are not official or authorized comments by LG Sciences, LLC.

  13.  07-31-2011  11:29 PM
    Registered User Blergs's Avatar
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    Originally Posted by Eyescream View Post
    My entire lower body is the injured area, though. How would I go about spot treatment with an injury of this magnitude?
    use 30-40mcg of IGF1LR3 it gose systemic. no need to pin a bunch of time. why some people still pin igf1 a bunch of times a day boggles my mind.
    LG Sciences Board Rep
    These statements have not been evaluated by the FDA, do not constitute medical advice, and are not official or authorized comments by LG Sciences, LLC.

  14.  08-01-2011  06:45 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by Grunt7684 View Post
    I'm pretty sure it has been demonstrated that ligaments don't have any IGF receptors, but that they do have GH receptors...

    i thought every tissue had igf-1 receptors

  15.  08-01-2011  06:47 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by Blergs View Post
    " It means that technically, for the part of the muscle in which you inject, THERE IS NO DIFFERENCE BETWEEN rhIGF-1 and Long R3 IGF-1. They both have the EXACT SAME LOCAL EFFECT. But rhIGF-1 gets neutralized quick, whereas Long R3 gets to float around until it finds a receptor."

    THANKYOU!!!! :-)

    longr3 does not last too long in the body. since it cannot bind to binding proteins it is susceptible to proteolytic cleavage

  16.  08-01-2011  06:47 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by Grunt7684 View Post
    I'm still around, kinda. I'm sick right now with extreme adrenal burnout and a concomitant metabolic disease, so I am mostly bedridden and most certainly cannot workout. So I am much less present on forums. But I hope to have all this fixed within a couple years and come back to my good ole habits.

    I am using this handle because my old Grunt76 handle got hijacked by a pirate/hacker some time back.
    take care of yourself man

  17.  08-01-2011  06:50 AM
    Featured Author Patrick Arnold's Avatar
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    Originally Posted by Blergs View Post
    1) 1) all igf1 or igf1lr3 go's systemic but igf1 gets cleared out fast in minutes and igf1lr3 is like 20hrs

    this is not true at all. in fact the opposite is true. regular igf-1 has a long half life and longr3 not as long


    people have had this misconception for long time. i think palumbo or someone was the guy that perpertrated the falsehood and it became brofact

  18.  12-01-2011  02:15 AM
    Registered User trenboloni's Avatar
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    Great... no, superb thread! I have four questions which I have in bold below.

    One question that's kind of been answered but is still debated: IGF-1r3long... PreWO or PostWO?

    I was thinking of pinning 40mcg bilaterally (20mcg + 20mcg), 3 times a week. The base of my cycle is test 500mg/wk, tren acetate 75mg/EOD. Basically the point of this cycle is body recomposition: more muscle, less fat. Very simple Diet will be in 2 week cycles and this will reflect in training methods as well: bulk, cut, bulk, cut... rinse and repeat until PCT starts at week 13.

    Also second question: will also include HGH, either the "standard" AM dosage, around 3iu ED AM... or 10iu PWO 2-3 times per week. If PWO, should I pin HGH PWO at the same days as I take IGF or pin IGF for example on Mon, Wed, Fri and HGH Tue, Thu, Sat?

    Any contraindications for taking a low dose T3 (25-50mcg ED for 12 weeks) with test, tren, HGH and IGF or is that old-school and/or dangerous?

    Taking HGH subQ and IGF IM, ok? Just asking this just in case I got something wrong, I am relying on "old" information, I have been out of the scene for 3-4 years or so. Please comment, thank you! My cycle starts at December 12th.

  19.  12-06-2011  10:30 AM
    Registered User francesco's Avatar
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    Originally Posted by Grunt76 View Post
    Having been informed that a sprain is a ligament injury, I will inform you in turn that sadly IGF-1 will not heal ligament. Cissus may help, and the proven ligament regenerators are: hGH, Anavar, Nandrolone and Boldenone. Testosterone above 200mg per week will inhibit the positive effects from those, though.



    I have used p-GH with very good results. From what I have read, p-GHt is equally a good product.
    I am looking into hgh for tendons stregthening/repairing, but i am on 600 mg test prop/week, does anybody have the knowledge to elaborate on the above statement?? if so which dose? is 2iu hgh 6/1 enough for my goal??? what is p-GH?

  20.  12-11-2011  08:05 PM
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    Most recommended igflr3 if u can find legit but it being so delicate makes it a bitch to handle. Also deca works
    ~ IRON LIVER™________ *[It's just advice man, that's all it is! You can take or do whatever the FCUK you wanna do!]

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