My take on IGF-1

r1ck · 10-23-2006, 01:08 PM

Quote:

Originally Posted by Grunt76

No, unless your estrogen is really high to begin with, and that's another matter entirely for sure.

should use some armidex .5 ed to stay estrogen low
with igf1-lr3

and since I have low lbm should i go stick 20mcg eod instead
of 30mcg

Grunt76 · 10-23-2006, 02:03 PM

Quote:

Originally Posted by r1ck

should use some armidex .5 ed to stay estrogen low
with igf1-lr3

and since I have low lbm should i go stick 20mcg eod instead
of 30mcg

Now there is a smart man. Start with 20mcg and run the first half of your mg at that dose if you get some good effects. Then kick it up to 30 if you feel you need more.

**TeamSavage** · 10-23-2006, 06:40 PM

Very interesting thread. Perhaps I'm missing something and this is a stupid question, but...

Since Long R3 IGF-1 is localized and binds to the closest receptors first, is it ideal to rotate the point of injection within a single muscle? In other words, if one is injecting pecs, should he just always inject in the center of the pectoral or should he sometimes inject on the upper portion, sometimes on the lower, etc? Thanks.

Jaxxx · 10-23-2006, 08:09 PM

For pecs injecting through the nipples works best.

mywetnightmares · 10-23-2006, 08:22 PM

If I want a systemic effect can I pin sub q. I ask because I worry about intestinal growth, but I'd only be pinning twice/week at 40 mcg or maybe 3 times/week at 30 mcg.

**TeamSavage** · 10-23-2006, 08:33 PM

Quote:

Originally Posted by Jaxxx

For pecs injecting through the nipples works best.

Thanks for the tip. I was just using pecs as an example though. Basically, I'm wondering if just injecting in the center of each muscle (pecs or otherwise) is sufficient and the IGF will be distributed throughout the muscle, or if it's preferable to inject in different areas on each injection to ensure effects are evenly distributed throughout that muscle.

**Ubiquitous** · 10-23-2006, 11:03 PM

Quote:

Originally Posted by TeamSavage

Thanks for the tip. I was just using pecs as an example though. Basically, I'm wondering if just injecting in the center of each muscle (pecs or otherwise) is sufficient and the IGF will be distributed throughout the muscle, or if it's preferable to inject in different areas on each injection to ensure effects are evenly distributed throughout that muscle.

I had wondered this, and tried different locations per muscle group. It can't hurt. Pecs, I keep one inch inside the nipple and go up from there accordingly. I keep to the thickest part of the pec.

Grunt76 · 10-24-2006, 01:16 AM

Quote:

Originally Posted by TeamSavage

Very interesting thread. Perhaps I'm missing something and this is a stupid question, but...

Since Long R3 IGF-1 is localized and binds to the closest receptors first, is it ideal to rotate the point of injection within a single muscle? In other words, if one is injecting pecs, should he just always inject in the center of the pectoral or should he sometimes inject on the upper portion, sometimes on the lower, etc? Thanks.

It is not ONLY localized. It was first designed to be a systemic drug and it will have some degree of systemic effect no matter what we do. Some slight systemic effect should be preferred, as it will help maintain tendons, cartilage, bone, internal organs and most soft tissue in good repair. The rest of the effect we want in the muscle. Too much systemic effec means that some of the LBM we are gaining comes from enlarged abdominal organs. I feel that rotating injection sites within a muscle is no effort at all, so why not.

Quote:

Originally Posted by mywetnightmares

If I want a systemic effect can I pin sub q. I ask because I worry about intestinal growth, but I'd only be pinning twice/week at 40 mcg or maybe 3 times/week at 30 mcg.

Systemic effect is the best way to grow guts. Injecting inside the muscle immediately postworkout ensures that it will primarily affect your muscle. That's what you want.

**Ubiquitous** · 10-24-2006, 03:49 AM

i need to spread some goddamn reps around before I hit you again Grunt.. but just know I love you.

Grunt76 · 10-24-2006, 02:00 PM

Quote:

Originally Posted by Ubiquitous

i need to spread some goddamn reps around before I hit you again Grunt.. but just know I love you.

W000h000 Someone loves me!

OK, I'm putting away the rat poison now...

joikd · 10-24-2006, 04:21 PM

I want no gut growth at all!!! I mean none. So, would using rhIGF-1 be the best way for me to go?

r1ck · 10-24-2006, 06:10 PM

Quote:

Originally Posted by joikd

I want no gut growth at all!!! I mean none. So, would using rhIGF-1 be the best way for me to go?

I would say no, because at low dosage 20mcg or 30mcg eod e3d you will destroy it in urine if you exceed what u need, your not going to take 100mcg a day of course because ull get the coleman gut of the beast, but ill let grunt ze master answer.

Grunt76 · 10-24-2006, 08:12 PM

Quote:

Originally Posted by joikd

I want no gut growth at all!!! I mean none. So, would using rhIGF-1 be the best way for me to go?

Just follow my protocol and you won't get any.

**TeamSavage** · 10-24-2006, 09:24 PM

Thanks for your previous response. Another issue on which I require clarification:

Let's say one is not focusing on a specific lagging muscle but wishes to hit most or all of the muscle groups...

I'm assuming the receptor downregulation only occurs on the muscle injected. Is this accurate? So if this is the case, then could you avoid downregulation even at 40mcg ED provided that each specific muscle group was only pinned E7D?

On a related issue, if one were pinning 40mcg ED but only hitting each muscle E7D, would you still recommend limiting to 4 week cycles?

Grunt76 · 10-25-2006, 01:21 AM

Quote:

Originally Posted by TeamSavage

Thanks for your previous response. Another issue on which I require clarification:

Let's say one is not focusing on a specific lagging muscle but wishes to hit most or all of the muscle groups...

I'm assuming the receptor downregulation only occurs on the muscle injected. Is this accurate? So if this is the case, then could you avoid downregulation even at 40mcg ED provided that each specific muscle group was only pinned E7D?

On a related issue, if one were pinning 40mcg ED but only hitting each muscle E7D, would you still recommend limiting to 4 week cycles?

There seems to be this huge problem with the idea that IGF-1 is both local and systemic. When you inject immediately postworkout in the muscle trained, most of the effect will go to the intended muscle, and there will be some degree of systemic spillover depending on your dosage.

For this reason, an EOD or E3D protocol is best. That is, not for any given muscle, but for any IGF-1 at all. You may get increased results by pinning the same muscle twice a week, provided you keep to an EOD or E3D pinning scheduled as indicated above.

**Mach .78** · 10-25-2006, 07:19 AM

It's been awhile since I been here(months). I've been reading up on all of this good info recently. I go and try to give Grunt some reps and I get denied. I have to spread it around before I can give anymore to you G. Good info on the IGF-1.