They should be good for a week, educated guesstimate.Originally Posted by not_big_enuf
Does IGF make you break out more, I seem to be getting alot more breakouts since I started the IGF.
I'm pretty sure it doesn't, my skin seems to have cleared up.
Yep that's a sign your IGF is legit.Originally Posted by mywetnightmares
The back of my patella is scuffed up from too many hang cleans. If I pin local to my knee after a workout will there be any benefit to my patella?
There should be. The only problem is, you cannot use acetic acid inside your knee. So you either have to use those 100mcg vials and reconstitute with NaCl solution, or my favorite solution is use of Oratropin-1 which goes EVERYWHERE in the body.Originally Posted by vin
"you cannot use acetic acid inside your knee"
Are you saying I can put it IN my knee? I was thinking the quads and hams...
Get Oratropin-1 sold by a sponsor here. It is a MUCH better idea bro. Seriously. Oratropin-1 is still Long R3 IGF-1, but it is absorbed in a completely different way, through the walls of the mouth and it goes into the lymphatic system rather than the circulatory system. From there, it sort of jumps from cell to cell, reaching places with about no blood circulation.Originally Posted by vin
Seriously man, get that one.
I checked out the ponsors but had no luck finding any. Is it still being made?
hey grunt whats your take on BSA[bovine serm albumin] in all forms of IGF? and the safty of inject?
I believe that Lion was the only one selling IGF with BSA. Needless to say lion wasn't a very good source to begin with so why you would buy from him is beyond me.
Moreover, Lion's stuff wasn't IGF-1 to begin with. It was just the part of the molecule that binds to the receptor. You need the whole peptide for actual effect. It was absolutely harmful sh!t that.Originally Posted by mywetnightmares
Simple: never ever buy Lion.
YGMOriginally Posted by vin
A few questions for you regarding IGF-1 theory:
1. I have seen a study indicating that an increase in circulating IGF-1 increases bone density. What are your thoughts on exogenous use having this effect? And would this effect only be while circulating levels are high and the density would go back to normal upon cessation of exogenous use.
2. It is generaly excepted that IGF-1 use will, and does create new muscle cells. And this will have a permanent effect on the user's total muscle cell count. But how are we sure that there is no negative feedback loop regarding the number of muscle cells in the body and the level of IGF-1 circulating? So when we cease the exogenous use of IGF-1 our body loses the extra created cells eventually? Because we already have a genetic base level of circulating IGF-1 - this level would seem to be supporting our own current muscle cell numbers. It seems logical to me that upon going back to our own genetic level of IGF-1, we would eventually go back to our predisposed cell count also. Cells die and get replicated all the time - our growth factor seems to depend on the rate that each of these occur. More creation than death means growth - and vice versa.
3. Since IGF-1 use has a negative feedback effect on ones own circulating HGH levels - why is HGH use (even in relatively small amounts) not recommended with the use of IGF-1? I know that IGF-1 is derived from HGH but it is only a portion of what HGH does. Will lower levels of HGH cause connective tissue issues for example? If you are taking IGF-1 EOD or E3D - what are it's effects on HGH levels over a long cycle such as 20 weeks? This protocal might have this as a side-effect. Just a thought.
I'm not a scientist - and I'm only just starting my research on this topic - but these are some questions that I have not seen answered in the Pubmed studies that I've read. I respect your knowledge on all issues regarding anabolic substances - so I tought I'd ask your thoughts.
No, bone density is increased from the added regenerative ability to bone from IGF-1. It will remain elevated, at least for a good while. GH secretagogues are being investigated for this exact effect from the IGF-1 generated from the extra gh.Originally Posted by Stupes
Hyperplasia is a rare thing. When I state "rare" I mean that you cannot expect a significant number of myotubes to undergo mitosis at any time you are supplementing IGF-1. Over time it does add up. But the IGF does much more than hyperplasia: it fuses the myoblasts to the myotubes, making them permanently bigger. From all I know about IGF-1 and muscle cells, even if you had minuscule systemic (paracrine) igf-1 levels, no muscle cell would die from that. You also should know that these cells themselves express IGF-1.Originally Posted by Stupes
GH use *IS* recommended with IGF-1. That's a simply great stack. GH is expensive for a lot of people though, so that would be the reason it isn't added to more igf cycles. Heck some people think IGF-1 is pricey.Originally Posted by Stupes
Those are some good questions bro, I hope I helped.
3. Since IGF-1 use has a negative feedback effect on ones own circulating HGH levels - why is HGH use (even in relatively small amounts) not recommended with the use of IGF-1?
yeah, i don't know where you got that from. I've gotten better results from a low-dose combo of the two than on either one alone. anyone who has tried them stacked will attest to the fact that they are synergistic.
if you suspect that you might have insulin insensativity would that make IGF LR3 work better or worse?
Pretty much the same.Originally Posted by skull
I suppose I worded my question stupidly - maybe I should have said - is HGH use a needed with the use of IGF-1? Does IGF-1 deplete HGH enough to have negative effects on tissue if you are on just IGF-1 for 8 weeks?Originally Posted by NattyNow
And what dosage and dosing scheme would be recommended for GH while on IGF-1 3x week at 40mcg a day?