
i read more recent articles on inclusion complexes of ursolic with cyclodextrins and i tried to make complexes myself. Its a dead end. A cursory glimpse of that patent suggests that they are using all kinds of surfactants and stuff along with the cyclodextrins to acheive a clear looking solution
the interior of cyclodextrin molecules have a polarity similar to methanol. so if your stuff dissolves in methanol (and is of the appropriate size for a particular cyclodextrin) it may form an inclusion complex. ursolic acid is virtually insoluble in methanol. therefore it just doesnt form inclusion complexes to any meaningful extent
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