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| | #61 |
| Registered User | To add to the prolactin discussion, what about SAM-e during and post-cycle? It has been shown to have positive effects on prolactin and dopamine levels, helps with hepatoxicity and can elevate mood. Plus methyl donors help with various reactions that can affect performance. |
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| | #62 | |
| Registered User | Quote:
![]() However, I have to admit that my line of thinking was more in terms of liver protection and mood and I was unaware of s-adenyl's affect on prolactin | |
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| | #63 | |
| Registered User | Quote:
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| | #64 |
| Registered User | My mistake. I just looked again and it is listed in your post-cycle supplements. I would like to point out that any info I pass along here is just from what I have read online; I am not trained in biochem or endocrinology and I am not presenting it as absolute fact. I try to only refer to reputable info that is scientifically referenced. With that said, here is an interesting abstract: J Psychiatry Res 1990;24(2):177-84 Neuroendocrine effects of S-adenosyl-L-methionine, a novel putative antidepressant. Fava M, Rosenbaum JF, MacLaughlin R, Falk WE, Pollack MH, Cohen LS, Jones L, Pill L Clinical Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114. S-adenosyl-L-methionine (SAMe), a putative antidepressant, is a naturally occurring substance whose mechanism of action is still a matter of speculation. It has been recently postulated that SAMe may increase the dopaminergic tone in depressed patients. Since dopamine inhibits both thyrotropin (TSH) and prolactin secretion, we investigated the effects of treatment with SAMe on the TSH and prolactin response to thyrotropin-releasing-hormone (TRH) stimulation in 7 depressed outpatient women (mean age: 46.1 +/- 7.2 years) and 10 depressed outpatient men (mean age: 38.0 +/- 10.0 years) participating in a six-week open study of oral SAMe in the treatment of major depression. At the end of the study, there was a significant reduction after treatment with SAMe in the response of both prolactin and TSH to TRH stimulation in the group of depressed men compared to pre-treatment values. On the other hand, in the group of depressed women, the posttreatment prolactin response to TRH did not appear to change when compared to pre-treatment and the TSH response to TRH challenge tended even to augment slightly after treatment with SAMe. Our results, at least in depressed men, seem to support the hypothesis of a stimulating effect of SAMe on the dopaminergic system. While this deals with a different population than we may be addressing here, it shows that SAM-e may affect prolactin levels through its positive actions on dopamine. The increase in dopamine should also benefit libido as previously discussed in this thread. Also some of the emotional effects of steroid cycles are probably linked to this pathway anyway, so it might be even more relevant. Also for anyone REALLY interested in neurotransmitters, check out this link: http://www.umsha.ac.ir/Vice%20Chance...20Function.pdf Sorry if this has gotten off topic. ![]() |
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| | #65 |
| Registered User | Messenger, this is actually the same SamE (see how clever phera makes me ) study my pharmacist printed out for me when I discussed SamE with him a few months ago. Good find bro!Day 16 A bit of lethargy is starting to set in. It's not debilitating, it just makes my aass feel too heavy to get up out of a chair. This has not affected my lifting whatsoever, but it has made light cardio very burdensome. My chest and lats seem to be progressing the most quickly to this point which I am very happy with. My shoulders and arms are looking a little fuller, although they are typically weaker points for me. Quads, calves, and traps are growing like crazy although these are typically very very strong parts for me that grow even with less emphasis. I actually dropped shrugs from my shoulder routine because my neck was disappearing ![]() I did decide that 40mg was the right dosage for me rather than staying at 30. I appreciate everyone's opinions and ALL of them were strongly considered in making this decision. My thought process was this: If I'm going to run a cycle, I want to put EVERYTHING into it and not sell myself short. I believe that I'm prepared to handle whatever sides show up, although I still expect minimal sides at this dosage. My entire life is dedicated to eating, sleeping, and training... so going all out with the supplement follows suite. |
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| | #66 |
| Muscle Pharm Rep | 40mg a day it is! MUSCLE PHARM........What's in your Arsenal?! Coupon code "pp30" to get great savings at Musclepharm . com |
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| | #67 | |
| Registered User | Quote:
That line made me smile!By the way Celc, congrats on naming your log after a Pink Floyd song. Bonus points for you! What is your plan of attack for the lethargy? Do you have stims on hand or are you planning on getting some? Curious to see if you can fend that off successfully. I hate signatures. | |
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| | #68 |
| Registered User | Sounds like your having great progress, this is making me very excited about my upcoming first run of PP. |
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| | #69 |
| Registered User | Piston, if I feel like things go haywire because of the dosage, I'd be sure to back off. I appreciate all of your feedback and hope that you continue to chime in often ![]() Hman, this stuff is SMOOTH to this point. IMO it has less sides and is less potent than the CEL halo clone... again, to THIS point. When it's all said and done, I expect this to be a tad more suppressive than halo. We'll see how this story unfolds. Ecto, I'm actually referencing a Rush bootleg called "Careful with that axe, Alex" which I'd bet is a reference to the said Pink Floyd song Btw, Alex is Alex Lifeson, the guitarist for Rush, which is Canada's second best contribution to the world after neoborn ![]() Also, here's the no BS explanation behind my strong points... body parts that have not been injured honestly don't reach plateau for me. I'd be able to shrug, squat, and deadlift in excess of 500 for reasonable reps if I did them on a regular basis, without hormones mind you. But, now that my personal focus has shifted from power and ego over to body composition, having poor balance is no longer productive. So, out go the shrugs for now. Re: lethargy, stims are out during this cycle. I'm guessing that the eratic sleep patterns from last week had something to do with the stims. I had some crazy chest pounding nights with anxiety but ONLY when I used a morning stim and/or a preworkout stim. My instinct was to "blame" the phera after all the controversy concerning BP and heart enlargement BLAH BLAH BLAH... ha! no stims, no issues. Btw, to anyone keeping score, resting heart rate has only went up about 5mm systolic since the start of the cycle. Negligible IMO. So, I've been using random non-stim supps that have beta alanine, occasionally some caffeine early in the day at work, and I'm just gonna man up and not be a puss. |
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| | #70 | |
| Registered User | Quote:
Great planning. This was done with alot of thought. You have everything in here and then some. Should be a great cycle. | |
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| | #71 | |
| Registered User | Quote:
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| | #72 | |
| Registered User | Quote:
Actually, rather than speculate on what someone else may or may not have recommended, feel free to contribute your own personal preference for taurine dosages. | |
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| | #73 | |
| Registered User | Quote:
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| | #74 |
| Registered User | hey celc5--- I thought you told me that you didn't get much out of activate extreme? I see you have it on your post cycle plan. I also see the form/trione combo. That I love!! I'm post cycle right now after a 3 week superdrol run that was fantastic at 30 mg. per day. I'm also taking the activate, ZMA, icariin, resveratrol and a few other goodies. I'm actually getting stronger in PCT. I have a suggestion on the stim issue. Try some B-12, fruit and a little honey pre-workout. It will help a little!! Have a great cycle celc5. My next run will be phera-plex as well at 30 mg. per day the whole 4 weeks. |
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| | #75 |
| Appnut at large Board Sponsor |