try to wait 30 minutes before eating. but it is not an absolute. dosing looks fine. regarding caffeine, this from the HEAT write up :
"Caffeine tends to be included in most thermogenics. It is cheap, it provides good stimulation, and it potentiates the effects of stimulants and catecholamine signaling via adenosine blockade (10, 11). Thus, it will increase short-term appetite suppression and help with fat loss peripherally, via norepinephrine and dopamine potentiation. It will make things even worse for the adipostat via NE but better via dopamine.
It also has negative effects on nutrient partitioning at the cellular level. Adenosine senses fuel availability, so antagonism tricks the cell into thinking it is full and energized. A full cell is a nutrient insensitive cell, so caffeine will inhibit nutrient uptake, and the excess will just float around and cause problems. High serum lipid and glucose levels are also strongly associated with obesity, insulin and leptin resistance, as well as cardiovascular disease (12, 13).
Because of the trade-offs, we went back and forth on caffeine, finally deciding to leave it out and just let the user have some coffee with it if they really wanted that extra kick. Coffee is yummy and part of a major social scene, anyway. Those who are pretty lean will get the most positives and least negatives from adding caffeine."
