DMAA Alternative

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  1. Adderall


  2. Quote Originally Posted by d33zLBoy
    Adderall
    Probably more dangerous than anything mentioned in this thread. Wouldn't touch it
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  3. Quote Originally Posted by jamesm11 View Post
    Probably more dangerous than anything mentioned in this thread. Wouldn't touch it
    seen its bad side in action with my girlfriend's son. Overly and indiscriminately prescribed
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  4. Quote Originally Posted by truthornothin View Post
    seen its bad side in action with my girlfriend's son. Overly and indiscriminately prescribed
    Yea.... Amphetamines are no joke lol

  5. We now have our latest product in stock, Pyro Rx with Geranimol ~ http://www.ironmaglabs.com/product-list/pyro-rx/
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  6. Quote Originally Posted by IronMagLabs
    We now have our latest product in stock, Pyro Rx with Geranimol ~ http://www.ironmaglabs.com/product-list/pyro-rx/
    Doesn't this have DMAA?

  7. Quote Originally Posted by jamesm11 View Post
    Doesn't this have DMAA?
    yes sir.

  8. Quote Originally Posted by IronMagLabs View Post
    We now have our latest product in stock, Pyro Rx with Geranimol ~ http://www.ironmaglabs.com/product-list/pyro-rx/
    Yohimbe and DMAA, sh*ts intense haha

  9. The bottom line is anybody can market and sell an "Ephedra" based product.... It just can't contain Ephedrine alkaloids. So all of these fat burners that have "Ephedra Leaf" and "Ephedra Extract" are just a bunch of shadily marketd bullcrap. If any of them do happen to contain Ephedrine alkaloids they're really asking for trouble from the feds IMO.

  10. Quote Originally Posted by IronMagLabs
    We now have our latest product in stock, Pyro Rx with Geranimol ~ ]
    Would you mind posting the actual ingredient dosages here? I know the FDA allows you to refer to a "proprietary blend", but it is really a cop out to those who read this forum.

  11. Quote Originally Posted by punisher55 View Post
    Would you mind posting the actual ingredient dosages here? I know the FDA allows you to refer to a "proprietary blend", but it is really a cop out to those who read this forum.
    this isn't really the place to do that
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  12. Quote Originally Posted by dmaa View Post
    I read all the threads and no one talk about dmaa replacement, very disappointed about that.
    Here I recommend some ingredients:
    1.dendrobium extract
    2.higenamine hcl
    3.hordenine hcl
    4.Caffeine
    5.Citrus Aurantium, or bitter orange (synephrine)
    6.Phenylethylamine
    7.N-methyltyramine(Methyltyramine, N-methyltyramine, or NMT)
    8. Theobromine
    9. N-Acetyl Tyrosine
    10.DMAE

    dendrobium extract 1% and higenamine hcl are the most popular ones recently.
    Methylsynephrine
    Acacia ridigula
    ...::: Olympus Labs Athlete & Representative :::...
    Crossfit - DEMIGOD -

  13. Quote Originally Posted by dmaa View Post
    I read all the threads and no one talk about dmaa replacement, very disappointed about that.
    Here I recommend some ingredients:
    1.dendrobium extract
    2.higenamine hcl
    3.hordenine hcl
    4.Caffeine
    5.Citrus Aurantium, or bitter orange (synephrine)
    6.Phenylethylamine
    7.N-methyltyramine(Methyltyramine, N-methyltyramine, or NMT)
    8. Theobromine
    9. N-Acetyl Tyrosine
    10.DMAE

    dendrobium extract 1% and higenamine hcl are the most popular ones recently.

    first of all, caffeine is not a replacement since all DMAA products are stacked with caffeine.

    Second of all, none of these ingredients do anything close to what DMAA does. some do have stim action but to match DMAA is just too tall an order for these.
    Anabolicminds.com Featured Author

  14. Phosphatidic acid is not a stimulant and higenamine, like any stimulant, can be toxic at the right dose.

  15. Quote Originally Posted by dmaa View Post
    By the way, could you common on higenamine hcl? Some said it is toxic, is it true?
    What a coincidence that you are asking about Higenamine, we are right now discussing this substance in one of the Swedish boards.

    Recently I found an interesting molecular property predictor which gives you 5 free predictions as a guest and if you register (for free) another 30 predictions, each month*. There are some interesting predictions under Toxicity and ADME.

    It appears that Higenamine have not so good bioavailability and at least in rats according to the study** it is metabolized to coclaurine and isococlaurine.

    If you do not want to draw the molecules yourself, you can copy following SMILES descriptors instead, by clicking on the smile symbol in the application.
    Higenamine: Oc1ccc(cc1)CC2NCCc3cc(O)c(O)cc 23
    Coclaurine: Oc1ccc(cc1)CC2NCCc3cc(OC)c(O)c c23

    It appears that both Higenamine and its metabolite Coclaurine are predicted as weak binding to Estrogen Receptor alpha (LogRBA between -3 and 0). Under Toxicity/Endocrine Disruption.

    A question to Patrick (and others): How useful would you say are such a molecular prediction property tools? Have you used them yourself sometimes?

    Due to the rules I cannot post links directly therefore you have to google it yourselfs.
    *The predictor name is ACD/I-Lab.
    **The title of the article is Identification of higenamine and its metabolites in rat by gas chromatography/mass spectrometry.

    EDIT: Somehow, there is introduced a gap in the end of SMILES, however when I try to correct it, the gap is nonexistent in the editing text. Therefore if you copy the SMILES, erase the gaps before use in the prediction tool.

  16. Quote Originally Posted by dmaa View Post
    well, you are all experts. I just follow suits. we only suppy ingredients, as sales, we are lack of such internal knowledge of the ingredients.
    Well I am not an expert and to clarify, I do not represent that company. I just found it interesting that there are such a tools online that gives you the opportunity for predicating properties of various molecules.

  17. Quote Originally Posted by dmaa View Post
    So do you have an ideal candidate for DMAA?
    One of my clients said Phosphatidic Acid is good enough,right?
    By the way, could you common on higenamine hcl? Some said it is toxic, is it true?
    You are an expert, we admire your comments.
    Thank you, patrick.

    i have no candidate

    phosphatidic acid will not give any stimulant activity

    people that tried higenamine have said it doesnt do much. i personally have not tried it. i know nothing of any toxicity
    Anabolicminds.com Featured Author

  18. Quote Originally Posted by Kelt View Post
    What a coincidence that you are asking about Higenamine, we are right now discussing this substance in one of the Swedish boards.

    Recently I found an interesting molecular property predictor which gives you 5 free predictions as a guest and if you register (for free) another 30 predictions, each month*. There are some interesting predictions under Toxicity and ADME.

    It appears that Higenamine have not so good bioavailability and at least in rats according to the study** it is metabolized to coclaurine and isococlaurine.

    If you do not want to draw the molecules yourself, you can copy following SMILES descriptors instead, by clicking on the smile symbol in the application.
    Higenamine: Oc1ccc(cc1)CC2NCCc3cc(O)c(O)cc 23
    Coclaurine: Oc1ccc(cc1)CC2NCCc3cc(OC)c(O)c c23

    It appears that both Higenamine and its metabolite Coclaurine are predicted as weak binding to Estrogen Receptor alpha (LogRBA between -3 and 0). Under Toxicity/Endocrine Disruption.

    A question to Patrick (and others): How useful would you say are such a molecular prediction property tools? Have you used them yourself sometimes?

    Due to the rules I cannot post links directly therefore you have to google it yourselfs.
    *The predictor name is ACD/I-Lab.
    **The title of the article is Identification of higenamine and its metabolites in rat by gas chromatography/mass spectrometry.

    i never used such a thing

    thanks for the tip
    Anabolicminds.com Featured Author

  19. Quote Originally Posted by Patrick Arnold View Post
    i never used such a thing

    thanks for the tip
    Ok, I understand. What I know is that most of the big pharma companies usually do some kind of prediction on all of their new designs. I presume that the synthesis costs both time and money so they probably want to see whether it is worth to even try.

    For us I would say it could be useful to get some kind of indication for the more “exotic” substances that are found in the supplements nowadays which do not have so many published papers about.

  20. The very first time I tried a product containing higenamine, I felt an ephedra-like boost and was able to run much faster than I normally do for the first 12-15 minutes of my run (which usually lasts longer than an hour). I didn't experience a huge crash when it wore off -- it was more like I just didn't feel the "boost" anymore. However, every time I have used the same product since then, I haven't felt anything at all. I guess I built tolerance to it REALLY fast.

  21. Quote Originally Posted by SpicedCider View Post
    The very first time I tried a product containing higenamine, I felt an ephedra-like boost and was able to run much faster than I normally do for the first 12-15 minutes of my run (which usually lasts longer than an hour). I didn't experience a huge crash when it wore off -- it was more like I just didn't feel the "boost" anymore. However, every time I have used the same product since then, I haven't felt anything at all. I guess I built tolerance to it REALLY fast.
    Unlikely, given the ~10 minute plasma HL in humans

  22. DMAA is still around and with the study showing its in geranium it may stick around for a bit.
    Anabolicminds.com Featured Author

  23. Quote Originally Posted by Patrick Arnold View Post
    DMAA is still around and with the study showing its in geranium it may stick around for a bit.
    You are lucky. Unfortunately in Sweden it has been classified as hazardous/harmful substance and therefor forbidden to sell, import or possess. The penalty for breaking the law can give up to one year in prison.

  24. Quote Originally Posted by Patrick Arnold View Post
    DMAA is still around and with the study showing its in geranium it may stick around for a bit.
    Unfortunately, my experience with DMAA was almost identical to my experience with higenamine. The first time I tried a product containing DMAA, it was actually your AMP product back in 2006. That first time was great. But ever since then, I haven't felt a thing from taking any product containing DMAA. Apparently my receptors must downregulate really fast or something.

  25. Quote Originally Posted by Kelt View Post
    You are lucky. Unfortunately in Sweden it has been classified as hazardous/harmful substance and therefor forbidden to sell, import or possess. The penalty for breaking the law can give up to one year in prison.
    Do they still allow you to smoke cigarettes there? hmmmm
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