DarkDescartes
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Hey guys, first time poster and new to the peaktestosterone forums.
I'm going to keep this brief.
I did 2 test only cycles in 3 months each within an 8 month period in 2015. No AI nor HCG and everything was fine. I came off the first cycle not feeling 100 percent and stupidly followed my friends advice (not friends anymore) about going back on and coming off correctly and or even better.
The cycle was going well up until week 9 when i experience hormonal dysfunctions for the first time: fatigue, ed & libido issues, depression, etc. I stopped, did some hcg which i dont know if it was quality at the time, did nolva and clomid after and havent been right since.
I touched nothing for a year and a half until September 2017 when i decided to seek medical help. I've tried all the natural methods, hcg restarts, and did hgh, all of which provided benefits within the first few days to a week and never to work the same way again.
I also started trt in april 2018, restarted 4 different times. I felt great the very first time for the first 3 weeks in, but not again afterwards. each time i restarted, id feel good the first few days and then it stops. I've been doing the trt-hcg-ai combo and it seems i quite possibly cant handle hcg with trt.
I've dropped hcg a couple of weeks ago and decided yesterday was the last AI use ill use. I'm scheduled for blood work in late october.
My most recent bloods are the following:06/06/2019 blood work:
TOTAL GLUTATHIONE 752 (544-1228 uM)
OMEGA 3 (EPA+DHA) 2.1 (2.2-3.2)
OMEGA 6/OMEGA 3 RATIO 12.3 (5.7-21.3)
EPA/ARACHIDONIC ACID RATIO <0.1 (0.2 OR LESS)
ARACHIDONIC ACID 11.3 (5.2-12.9 %)
EPA 0.3 (0.2-1.5 %)
DHA 1.8 (1.2-3.9 %)
OSMOLALITY,SERUM 290 (275-295 mOsm/kg H2O)
MAGNESIUM 2.0 (1.5-2.5 mg/dL)
FIBRINOGEN ACTIV,CLAUSS FIBRINOGEN 237 (175-425 mg/dL)
FSH <0.7 L (1.6-8.0 mIU/mL)
LH <0.2 L (1.5-9.3 mIU/mL)
THYROID PEROXIDASE AB <1 <9 IU/mL
THYROGLOBULIN ANTIBODIES <1 < OR = 1 IU/mL
CERULOPLASMIN 31 (18-36 mg/dL)
VITAMIN C 0.7 (0.2-2.1 mg/dL)
TNF-ALPHA,HIGHLY SENSITIVE 0.54 L (0.56-1.40 pg/mL)
ESTRADIOL, ULTRASEN,LC/MS 51 H
DIHYDROTESTOSTERON,LCMSMS 64 (16-79 ng/dL)
TESTOSTERONE,TOTAL, MS 1387 H (250-1100 ng/dL)
TESTOSTERONE,FREE 274.6 H (35.0-155.0 pg/mL)
17-HYDROXYPROGESTERONE 40 (32-307 ng/dL)
VITAMIN A (RETINOL) 46 (38-98 mcg/dL)
IMMUNOGLOBULIN A 150 (81-463 mg/dL)
SEX HORMONE BINDING GLOB 41 (10-50 nmol/L)
WBC 2.9 L (3.8-10.8 Thousand/uL)
RBC 5.95 H (4.20-5.80 Million/uL)
HEMOGLOBIN 16.3 (13.2-17.1 g/dL)
HEMATOCRIT 49.5 (38.5-50.0 %)
MCV 83.2 (80.0-100.0 fL)
MCH 27.4 (27.0-33.0 pg)
MCHC 32.9 (32.0-36.0 g/dL)
RDW 15.3 H (11.0-15.0 %)
PLATELET COUNT 231 (140-400 Thousand/uL)
MPV 9.9 (7.5-12.5 fL)
TOTAL NEUTROPHILS,% 46.8 (38-80 %)
TOTAL LYMPHOCYTES,% 42.3 (15-49 %)
MONOCYTES,% 6.8 (0-13 %)
EOSINOPHILS,% 3.4 (0-8 %)
BASOPHILS,% 0.7 (0-2 %)
NEUTROPHILS,ABSOLUTE 1357 L (1500-7800 cells/uL)
LYMPHOCYTES,ABSOLUTE 1227 (850-3900 cells/uL)
MONOCYTES,ABSOLUTE 197 L (200-950 cells/uL)
EOSINOPHILS,ABSOLUTE 99 (15-500 cells/uL)
BASOPHILS,ABSOLUTE 20 (0-200 cells/uL)
ACTH,PLASMA 33 (6-50 pg/mL)
HEMOGLOBIN A1C 5.3 (<5.7 % of total Hgb)
COPPER 124 (70-175 mcg/dL)
MAGNESIUM,RBC 4.5 (4.0-6.4 mg/dL)
SELENIUM 142 (63-160 mcg/L)
ZINC 63 (60-130 mcg/dL)
VITAMIN B6, PLASMA 38.0 H (2.1-21.7 ng/mL)
VEGF,ELISA QNI VASCULAR ENDOTHELIAL GF <31 L (31-86 pg/mL)
HUMAN TGF BETA 1 (TGF-B1) 15460 H (344-2382 pg/mL)
VITAMIN B1 (THIAMINE), B 76 L (78-185 nmol/L)
VITAMIN E (TOCOPHEROL) AMD ALPHA-TOCOPHEROL 12.9 (5.7-19.9 mg/L)
Comp Metab Panel
GLUCOSE,FASTING 91 (65-99 mg/dL)
SODIUM 139 (135-146 mmol/L)
POTASSIUM 4.3 (3.5-5.3 mmol/L)
CHLORIDE 105 (98-110 mmol/L)
CARBON DIOXIDE 30 (20-32 mmol/L)
UREA NITROGEN 17 (7-25 mg/dL)
CREATININE 1.33 (0.60-1.35 mg/dL)
CALCIUM 9.4 (8.6-10.3 mg/dL)
PROTEIN, TOTAL 6.9 (6.1-8.1 g/dL)
ALBUMIN 4.4 (3.6-5.1 g/dL)
GLOBULIN 2.5 (1.9-3.7 g/dL) (calc)
ALBUMIN/GLOBULIN RATIO 1.8 (1.0-2.5) (calc)
BILIRUBIN,TOTAL 0.6 (0.2-1.2 mg/dL)
ALKALINE PHOSPHATASE 109 (40-115 U/L)
AST 37 (10-40 U/L)
ALT 28 (9-46 U/L)
EGFR NON AFR AMERICAN 73 >=60 mL/min/1.73m2
EGFR AFRICAN AMERICAN 85 >=60 mL/min/1.73m2
LIPID PANEL
CHOLESTEROL,TOTAL 175 (<200 mg/dL)
HDL CHOLESTEROL 62 (>40 mg/dL)
CHOLESTEROL/HDL RATIO 2.8 (<5.0 calc)
LDL-CHOLESTEROL 101 H (<100 mg/dL) (calc)
TRIGLYCERIDES 41 (<150 mg/dL)
NON HDL CHOLESTEROL 113 (<130 mg/dL) (calc)
GGT 10 (3-70 U/L)
IRON,TOTAL 75 (50-195 mcg/dL)
IRON BINDING CAPACITY 298 (250-425 mcg/dL) (calc)
IRON % SATURATION 25 (15-60 %)
TSH 1.34 (0.40-4.50 mIU/L)
T4,FREE 1.1 (0.8-1.8 ng/dL)
T3,FREE 3.0 (2.3-4.2 pg/mL)
LIPASE 46 (7-60 U/L)
FERRITIN 59 (20-345 ng/mL)
PROGESTERONE 0.5 (<1.4 ng/mL)
VITAMIN B12 510 (200-1100 pg/mL)
FOLATE,SERUM 13.4 (> 5.4 ng/mL)
CORTISOL (AM) 11.8 (4.0-22.0 mcg/dL)
INSULIN 3.0 (2.0-19.6 uIU/mL)
DHEA SULFATE 392 (85-690 mcg/dL)
HS CRP 0.8 mg/L
HOMOCYSTEINE 7.6 (<11.4 umol/L)
VITAMIN D,25-OH,TOTAL,IA 52 (30-100 ng/mL)
INTERLEUKIN-6(IL-6),SERUM <1.40 (<5.00 pg/mL)
PREGNENOLONE,LC/MS/MS 62 (22-237 ng/dL)
T3 REVERSE, LC/MS/MS 14 (8-25 ng/dL)
VIP <50 (<75 pg/mL)
Besides the obvious in terms of my test being a bit too high and my T/E2 ratio still off, I'd like to know if theres anything here that anybody sees that i could build a possible diagnosis from and begin to cure.
TGF1-Beta & VEGF are weirdly off and nothing online nor any doctor can tell me what it means.
I'm supplementing with pregnenolone, did a course of ferritin supplementation.
My trt dose for the next 2 months will be 100mg twice a week, no hcg, no ai.
Anybody got any suggestions on where to go from here besides waiting for my next round of bloods?
Modify message
I'm going to keep this brief.
I did 2 test only cycles in 3 months each within an 8 month period in 2015. No AI nor HCG and everything was fine. I came off the first cycle not feeling 100 percent and stupidly followed my friends advice (not friends anymore) about going back on and coming off correctly and or even better.
The cycle was going well up until week 9 when i experience hormonal dysfunctions for the first time: fatigue, ed & libido issues, depression, etc. I stopped, did some hcg which i dont know if it was quality at the time, did nolva and clomid after and havent been right since.
I touched nothing for a year and a half until September 2017 when i decided to seek medical help. I've tried all the natural methods, hcg restarts, and did hgh, all of which provided benefits within the first few days to a week and never to work the same way again.
I also started trt in april 2018, restarted 4 different times. I felt great the very first time for the first 3 weeks in, but not again afterwards. each time i restarted, id feel good the first few days and then it stops. I've been doing the trt-hcg-ai combo and it seems i quite possibly cant handle hcg with trt.
I've dropped hcg a couple of weeks ago and decided yesterday was the last AI use ill use. I'm scheduled for blood work in late october.
My most recent bloods are the following:06/06/2019 blood work:
TOTAL GLUTATHIONE 752 (544-1228 uM)
OMEGA 3 (EPA+DHA) 2.1 (2.2-3.2)
OMEGA 6/OMEGA 3 RATIO 12.3 (5.7-21.3)
EPA/ARACHIDONIC ACID RATIO <0.1 (0.2 OR LESS)
ARACHIDONIC ACID 11.3 (5.2-12.9 %)
EPA 0.3 (0.2-1.5 %)
DHA 1.8 (1.2-3.9 %)
OSMOLALITY,SERUM 290 (275-295 mOsm/kg H2O)
MAGNESIUM 2.0 (1.5-2.5 mg/dL)
FIBRINOGEN ACTIV,CLAUSS FIBRINOGEN 237 (175-425 mg/dL)
FSH <0.7 L (1.6-8.0 mIU/mL)
LH <0.2 L (1.5-9.3 mIU/mL)
THYROID PEROXIDASE AB <1 <9 IU/mL
THYROGLOBULIN ANTIBODIES <1 < OR = 1 IU/mL
CERULOPLASMIN 31 (18-36 mg/dL)
VITAMIN C 0.7 (0.2-2.1 mg/dL)
TNF-ALPHA,HIGHLY SENSITIVE 0.54 L (0.56-1.40 pg/mL)
ESTRADIOL, ULTRASEN,LC/MS 51 H
DIHYDROTESTOSTERON,LCMSMS 64 (16-79 ng/dL)
TESTOSTERONE,TOTAL, MS 1387 H (250-1100 ng/dL)
TESTOSTERONE,FREE 274.6 H (35.0-155.0 pg/mL)
17-HYDROXYPROGESTERONE 40 (32-307 ng/dL)
VITAMIN A (RETINOL) 46 (38-98 mcg/dL)
IMMUNOGLOBULIN A 150 (81-463 mg/dL)
SEX HORMONE BINDING GLOB 41 (10-50 nmol/L)
WBC 2.9 L (3.8-10.8 Thousand/uL)
RBC 5.95 H (4.20-5.80 Million/uL)
HEMOGLOBIN 16.3 (13.2-17.1 g/dL)
HEMATOCRIT 49.5 (38.5-50.0 %)
MCV 83.2 (80.0-100.0 fL)
MCH 27.4 (27.0-33.0 pg)
MCHC 32.9 (32.0-36.0 g/dL)
RDW 15.3 H (11.0-15.0 %)
PLATELET COUNT 231 (140-400 Thousand/uL)
MPV 9.9 (7.5-12.5 fL)
TOTAL NEUTROPHILS,% 46.8 (38-80 %)
TOTAL LYMPHOCYTES,% 42.3 (15-49 %)
MONOCYTES,% 6.8 (0-13 %)
EOSINOPHILS,% 3.4 (0-8 %)
BASOPHILS,% 0.7 (0-2 %)
NEUTROPHILS,ABSOLUTE 1357 L (1500-7800 cells/uL)
LYMPHOCYTES,ABSOLUTE 1227 (850-3900 cells/uL)
MONOCYTES,ABSOLUTE 197 L (200-950 cells/uL)
EOSINOPHILS,ABSOLUTE 99 (15-500 cells/uL)
BASOPHILS,ABSOLUTE 20 (0-200 cells/uL)
ACTH,PLASMA 33 (6-50 pg/mL)
HEMOGLOBIN A1C 5.3 (<5.7 % of total Hgb)
COPPER 124 (70-175 mcg/dL)
MAGNESIUM,RBC 4.5 (4.0-6.4 mg/dL)
SELENIUM 142 (63-160 mcg/L)
ZINC 63 (60-130 mcg/dL)
VITAMIN B6, PLASMA 38.0 H (2.1-21.7 ng/mL)
VEGF,ELISA QNI VASCULAR ENDOTHELIAL GF <31 L (31-86 pg/mL)
HUMAN TGF BETA 1 (TGF-B1) 15460 H (344-2382 pg/mL)
VITAMIN B1 (THIAMINE), B 76 L (78-185 nmol/L)
VITAMIN E (TOCOPHEROL) AMD ALPHA-TOCOPHEROL 12.9 (5.7-19.9 mg/L)
Comp Metab Panel
GLUCOSE,FASTING 91 (65-99 mg/dL)
SODIUM 139 (135-146 mmol/L)
POTASSIUM 4.3 (3.5-5.3 mmol/L)
CHLORIDE 105 (98-110 mmol/L)
CARBON DIOXIDE 30 (20-32 mmol/L)
UREA NITROGEN 17 (7-25 mg/dL)
CREATININE 1.33 (0.60-1.35 mg/dL)
CALCIUM 9.4 (8.6-10.3 mg/dL)
PROTEIN, TOTAL 6.9 (6.1-8.1 g/dL)
ALBUMIN 4.4 (3.6-5.1 g/dL)
GLOBULIN 2.5 (1.9-3.7 g/dL) (calc)
ALBUMIN/GLOBULIN RATIO 1.8 (1.0-2.5) (calc)
BILIRUBIN,TOTAL 0.6 (0.2-1.2 mg/dL)
ALKALINE PHOSPHATASE 109 (40-115 U/L)
AST 37 (10-40 U/L)
ALT 28 (9-46 U/L)
EGFR NON AFR AMERICAN 73 >=60 mL/min/1.73m2
EGFR AFRICAN AMERICAN 85 >=60 mL/min/1.73m2
LIPID PANEL
CHOLESTEROL,TOTAL 175 (<200 mg/dL)
HDL CHOLESTEROL 62 (>40 mg/dL)
CHOLESTEROL/HDL RATIO 2.8 (<5.0 calc)
LDL-CHOLESTEROL 101 H (<100 mg/dL) (calc)
TRIGLYCERIDES 41 (<150 mg/dL)
NON HDL CHOLESTEROL 113 (<130 mg/dL) (calc)
GGT 10 (3-70 U/L)
IRON,TOTAL 75 (50-195 mcg/dL)
IRON BINDING CAPACITY 298 (250-425 mcg/dL) (calc)
IRON % SATURATION 25 (15-60 %)
TSH 1.34 (0.40-4.50 mIU/L)
T4,FREE 1.1 (0.8-1.8 ng/dL)
T3,FREE 3.0 (2.3-4.2 pg/mL)
LIPASE 46 (7-60 U/L)
FERRITIN 59 (20-345 ng/mL)
PROGESTERONE 0.5 (<1.4 ng/mL)
VITAMIN B12 510 (200-1100 pg/mL)
FOLATE,SERUM 13.4 (> 5.4 ng/mL)
CORTISOL (AM) 11.8 (4.0-22.0 mcg/dL)
INSULIN 3.0 (2.0-19.6 uIU/mL)
DHEA SULFATE 392 (85-690 mcg/dL)
HS CRP 0.8 mg/L
HOMOCYSTEINE 7.6 (<11.4 umol/L)
VITAMIN D,25-OH,TOTAL,IA 52 (30-100 ng/mL)
INTERLEUKIN-6(IL-6),SERUM <1.40 (<5.00 pg/mL)
PREGNENOLONE,LC/MS/MS 62 (22-237 ng/dL)
T3 REVERSE, LC/MS/MS 14 (8-25 ng/dL)
VIP <50 (<75 pg/mL)
Besides the obvious in terms of my test being a bit too high and my T/E2 ratio still off, I'd like to know if theres anything here that anybody sees that i could build a possible diagnosis from and begin to cure.
TGF1-Beta & VEGF are weirdly off and nothing online nor any doctor can tell me what it means.
I'm supplementing with pregnenolone, did a course of ferritin supplementation.
My trt dose for the next 2 months will be 100mg twice a week, no hcg, no ai.
Anybody got any suggestions on where to go from here besides waiting for my next round of bloods?
Modify message
Last edited: