Quick question guys. Does anyone know whether SSRI induced gyno is the result of increased serotonin or is it due to the chemical makeup or metabolites of the drug itself?? I've been off and on SSRI's since 2004, but have recently come off them altogether. I started taking 5-HTP which seems to be a more natural feeling alternative to the drugs. I have always battled with mild gyno symptoms and believe its because of the SSRI's. Since being off Zoloft now, the puffy nipples seem to be less common now then they were. Any ideas??