Look at the cohort - 52kg young woman! It ain’t gonna be that low stacked on anyone of any consequential size on gear. She should be 100/70.
What do you mean how it affects prep? If you can’t control BP, you are damaging kidneys. You wear those out and you are out of this game. So you may have to take more drugs to control bp because you are pushing it harder with the nicotine in the stack. If it were me, I would rather take less bp meds, be healthier at the given dose of bp meds, or take more gear for the same higher bp that gear+nicotine would be.
The flip side of course is if you are already addicted, pulling the appetite suppression you already get from nicotine while also prepping is asking for a failed diet.