mr.cooper69
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With that dose of aspirin, you are good to go . Go too high and you risk negative effects completely unrelated to the EC stack.The purpose of the aspirin is to inhibit prostaglandin production which helps to enhance and prolong the effects of EC. The purpose of ephedrine is to increase the release of adrenaline and noradrenaline. Problem is noradrenaline is inhibited by prostaglandins and adenosine. This is where caffeine and aspirin come in. Aspirin inhibits the peripheral synthesis of prostaglandins and caffeine antagonizes adenosine. Basically the aspirin and caffeine disrupt the negative feedback loops and allows for the optimal release noradrenaline.
Is aspirin NEEDED? No. Is caffeine NEEDED? Yes! As Easy said above, the extent of how much of a difference the addition of aspirin actually makes with regards to enhanced fat burning has been questionable and for those who are sensitive to aspirin E+C is still pretty effective. Caffeine works to antagonizes adenosine and also antagonizes phosphodiesterase (which is important for ensuring optimal cAMP levels)
From my experience with ECA, I have noticed better fat loss with the aspirin. Personally I take only one 81mg enteric-coated aspirin with my morning dose of ECA and the remaining doses are just EC.