awesome thanks..i just have a few more questions..is it true that once i start helping out this help i should start up doing the other pathways with like b12 and folic acid,..but i shouldnt do that until i have fixed this cbs pathway right..or else things will just get worse. I dont have time to get all those tests but i knwow b6 and zinc have always helped me more than any others supps. Sometimes back to normal. My only question would be about the NAC, how does that help with the cbs pathway..and how long does it usually take to get this one going before moving on to the other things and adding in some sulfur components to help detoxify..Really appreciate your help hardasnails..This stuff is pretty tought for me to understand but I am young and if i can fix my body with this stuff rather than hormones and injections, i would SOO rather do it that way. Thanks again
well problem is you need to identify where the block is.
Sam-e gets things going goes into homocysteine then homocystein can be broken down into 3 ways
1.CBS - magnesium, p5p, nac
2. MS - methy b-12, folonic acid
3. BHMT - TMG and PC
problem is to find the hole and plug it.
my hole was in methyation reason being hidden build up of 16 and 4 hydrox and imagnesium,iodine defiency (from not salting my foods for almost 2 decades) causing metabolic blockage and depletion of methyl groups. This was shown with high sarconsine in urine that idenitifed FUNCTIONAL folic acid defiency. I was like WTF i have all this folic acid in my blood but still deficient. Drs were baffled and could not explain it but after dilgenit research it was just telling me I was an undermethyator and nto converting it to its ACTIVE FORM. When I first got sick i pissed out high amounts of xylene and the remedy what glycine even at high dosages it did not work. Upon futher investigation this was idenitfy a screw up in estrogen metabolism and gluthione production. I could not for life of me understand why i felt estrogen dominant but had normal e2 reasdings in the blood.
Point blank people with low iodine levels are undermethyators due to the fact iodine bleeds out th 16 hydrox into estriol if it does not then you get a build up of 16 hydrox and if your can not methyate you get a back log.
Think about it what factors affect cancer
1. alteration of methyation of DNA - CBS and MS, BHMT imbalances due to enviorment, genetics, diet, stress
2. iodine defiency
3. fukd estrogen metabolism -due to enviroment or mineral imbalances
4. alkalinity of the body - goes back to step 1 diet affects DNA polymorphism
So to wrap it up nicely our own lifestyles and how we chose to deal with the issues of today will affect our chances of getting cancer which has been shown to be prevented and even in some cases reversed through life style changes and nutritional intervention
Why i mainly emphassis
1. slow down enjoy life
2. take time out for your self at least 20 minutes 1-2 times a day and just practice belly breathing and clear mind
3. wake up with sun goto bed in dark (no computer after sun goes down)
4. alkaline diet - 80% alkaline 20% acid
5. 1/2 hour or more of sun a day if not up to 4000 ius vitamin D in the winter time starting in september and get vitamin D levels check should be about 60 or higher for optimal health
6. find a job that you enjoy and can look forward to every day.
7. have a super being to believe in because faith is a very powerful thing and this aspect of life is very forgotten these days and is one of th emost important...