Let's talk about Defuse.

ma70

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Seems like an underrated supplement that could be useful for more than just cheat meals. I got some for a good deal and figure I'd try it on a mass gaining phase. Basic recommendations for Defuse are 3-4 weeks max at using the full dosage (4 caps, 2x a day) and I've heard some use 4 caps 1x a day for a much longer duration. Since Defuse doesn't actually prevent nutrient absorption and just stops fat gain from happening, I think this would be great for a lean bulk. Anyone else try it like this? I've only seen 1-2 posters using it like this.
 
LeanEngineer

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I personally havent used it so i cant say anything with my opinion but in to see how it works.
 
Driven2lift

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I wouldn't use it in a bulk.

Are there mechanisms that could be useful? Sure

Generally speaking a lot of these same mechanisms also inhibit hypertrophy.

+antioxidants
+ dsade recommended not to use too long

This us a great supplement for being able to minimize damage from cheat meals but not for continual use, IMO.
 

ma70

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I wouldn't use it in a bulk.

Are there mechanisms that could be useful? Sure

Generally speaking a lot of these same mechanisms also inhibit hypertrophy.

+antioxidants
+ dsade recommended not to use too long

This us a great supplement for being able to minimize damage from cheat meals but not for continual use, IMO.
I didn't know it had antioxidants. Hmm. I guess it could be dosed far away from workouts, but also, like I said, dsade recommends a maximum of 21 days on full dosage. I figure you could have a planned mass gaining phase where you beat the crap out of yourself for 3 weeks then deload, haha.
 
JudoJosh

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I have been meaning to try it but unfortunately haven't had a chance to :(
 
digitalducki

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I tried it last year when I went on vacation. I definetly gained fat, but it came off rather quickly when I returned to diet and training. I have another vaca coming up in May and I'll get another bottle
 
Geoforce

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It was designed for the purpose of damage control for huge cheat meals and that is the best purpose for it. Matt has said it could be used during a bulk, but this is definitely not a long term use product. It's best to use all at once or sporadically for big cheat meals (that's how I use it). It will inhibit fat gain, but it is not going to keep a 5000 calorie meal from having an effect. The goal is to lessen the effect of that giant cheat.

You can read more on the write-up and the science here.

http://anabolicminds.com/forum/evomuse/238248-evomuse-defuse-writeup.html

We have more feedback on people who use it to mitigate fat gain while cutting, but that doesn't mean it can't be effective on a bulk. I would have to dig around our feedback to see if we have some people who have done that.
 
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