Grape Seed Extract as an AI - dosage recommendations

felixfly

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I'm looking for some advice on using grape seed extract as an AI. E2 isn't too bad (47), but needs to come down. Dex is just really bad news for me - feel like crap on it. Anyone have some guidelines they can share?
 
rms80

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I'm looking for some advice on using grape seed extract as an AI. E2 isn't too bad (47), but needs to come down. Dex is just really bad news for me - feel like crap on it. Anyone have some guidelines they can share?
100 to 300 mg/day seems to help some....
 
Steveoph

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I dose at 100mg , 2x daily just for the anti-oxidant benefits. I would suggest looking into other compounds that are stronger AI's, Trione, ATD, 6-Bromo and Formestane are great options.
 

felixfly

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100 to 300 mg/day seems to help some....
I should have mentioned I've also added 100mg of zinc for the same purpose. I'll try the 300 mg. I really would like to get below 30 on the e2 but the dex causes problems. I read on another board it inhibits some good estrogens as well. I'm a TRT guy, not on a cycle, so a strong Ai is probably going to be too much.

Thanks for the feedback! I'd love to hear from anyone else using GSE and zinc in combination.
 
pistonpump

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hit up the broccoli man! its a good source of zinc and i3c

Like other cruciferous vegetables, broccoli contains the phytonutrients sulforaphane and the indoles, which have significant anti-cancer effects. Research on indole-3-carbinol shows this compound helps deactivate a potent estrogen metabolite (4-hydroxyestrone) that promotes tumor growth, especially in estrogen-sensitive breast cells, while at the same time increasing the level of 2-hydroxyestrone, a form of estrogen that can be cancer-protective. Indole-3-carbinol has been shown to suppress not only breast tumor cell growth, but also cancer cell metastasis (the movement of cancerous cells to other parts of the body).
 

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