GH reduces 11beta-HSD1 activity, here is an article that explains everythign about it. Long fun read...
Log In Problems
once you are done with reading all that, now it doesnt make any sense why people hold water at their feet and hands if GH is supposed to lower cortisol.
what i am thinking is that 11bHSD1 activity goes down, there are alot of aldosterone and cortisone around, so if the big bad boss (cortisol) is out of the picture the little guys will dominate causing water retention? at this point 11bHSD2 doesnt have any control over it at Kidney (mineralocorticoids receptors in play with cortisone/cortisol/aldosterone etc)
any thoughts?
bobaslaw? LOL
Log In Problems
once you are done with reading all that, now it doesnt make any sense why people hold water at their feet and hands if GH is supposed to lower cortisol.
what i am thinking is that 11bHSD1 activity goes down, there are alot of aldosterone and cortisone around, so if the big bad boss (cortisol) is out of the picture the little guys will dominate causing water retention? at this point 11bHSD2 doesnt have any control over it at Kidney (mineralocorticoids receptors in play with cortisone/cortisol/aldosterone etc)
any thoughts?
bobaslaw? LOL