Data on amyotrophic lateral sclerosis published by researchers at National Institute of Neurological Disorders and Stroke
09-28-07
"The etiology of several neurodegenerative disorders is thought to involve impaired mitochondrial function and oxidative stress. Coenzyme Q-10 (CoQ(10)) acts both as an antioxidant and as an electron acceptor at the level of the mitochondria," researchers in the United States report.
"In several animal models of neurodegenerative diseases including amyotrophic lateral sclerosis, Huntington's disease, and Parkinson's disease, CoQ(10) has shown beneficial effects. Based on its biochemical properties and the effects in animal models, several clinical trials evaluating CoQ(10) have been undertaken in many neurodegenerative diseases," wrote W.R. Galpern and colleagues, National Institute of Neurological Disorders and Stroke.
The researchers concluded: "CoQ(10) appears to be safe and well tolerated, and several efficacy trials are planned."
Galpern and colleagues published their study in Mitochondrion (Coenzyme Q treatment of neurodegenerative diseases of aging. Mitochondrion, 2007;7(Suppl. S):S146-S153).
09-28-07
"The etiology of several neurodegenerative disorders is thought to involve impaired mitochondrial function and oxidative stress. Coenzyme Q-10 (CoQ(10)) acts both as an antioxidant and as an electron acceptor at the level of the mitochondria," researchers in the United States report.
"In several animal models of neurodegenerative diseases including amyotrophic lateral sclerosis, Huntington's disease, and Parkinson's disease, CoQ(10) has shown beneficial effects. Based on its biochemical properties and the effects in animal models, several clinical trials evaluating CoQ(10) have been undertaken in many neurodegenerative diseases," wrote W.R. Galpern and colleagues, National Institute of Neurological Disorders and Stroke.
The researchers concluded: "CoQ(10) appears to be safe and well tolerated, and several efficacy trials are planned."
Galpern and colleagues published their study in Mitochondrion (Coenzyme Q treatment of neurodegenerative diseases of aging. Mitochondrion, 2007;7(Suppl. S):S146-S153).