heres one study
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Title: The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome.
Author: Oben J , Kuate D , Agbor G , Momo C , Talla X
Source: Lipids Health Dis, 5(): 24 2006
Service Fee: $12.00 ; Copyright Royalties: $0.00
Abstract: AIM: Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. METHODS: The study was a randomized, double-blind, placebo-controlled design involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19-50). The 92 obese (BMI >30) participants were randomized into three groups; placebo, formulation/no diet, and formulation/diet (2100-2200 calories/day). The 31 overweight participants (BMI = 25-29) formed a fourth (no diet) treatment group. All participants received two daily doses of the formulation or placebo and remained on a normal or calorie-controlled diet for 8 weeks. RESULTS: At the end of the trial period, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein were observed in participants who received the formulation, regardless of diet. CONCLUSION: Cissus quadrangularis formulation appears to be useful in the management of weight loss and metabolic syndrome.
Language: eng
Unique Identifier:
MajorMeSH Heading: Diet, Reducing
MinorMeSH Heading Adult, Anti-Obesity Agents, Blood Glucose, Body Mass Index, Body Weight, Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Cissus, Diarrhea, Double-Blind Method, Female, Headache, Humans, Male, Metabolic Syndrome X, Middle Aged, Obesity, Overweight, Plant Extracts, Prospective Studies, Treatment Outcome, Triglycerides, Weight Loss,
--------------------------------------------------------------------------------
Publication Type: Journal Article
ISSN: 1476511X
Country of Publication: England
heres another(noting it decreases fatloss,improves health and lipid profile , cardiovasuclar function and builds muscle mass. one nice combo.
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New Search Save Article Save Query: cissus
Place in Cart Email Citation
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Title: The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress.
Author: Oben JE , Enyegue DM , Fomekong GI , Soukontoua YB , Agbor GA
Source: Lipids Health Dis, 6(): 4 2007
Service Fee: $12.00 ; Copyright Royalties: $0.00
Abstract: AIM: Obesity is generally linked to complications in lipid metabolism and oxidative stress. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a proprietary formulation containing CQR-300 (CORE) on weight, blood lipids, and oxidative stress in overweight and obese people. METHODS: The first part of the study investigated the in vitro antioxidant properties of CQR-300 and CORE using 3 different methods, while the second part of the study was a double-blind placebo controlled design, involving initially 168 overweight and obese persons (38.7% males; 61.3% females; ages 19-54), of whom 153 completed the study. All participants received two daily doses of CQR-300, CORE, or placebo and were encouraged to maintain their normal levels of physical activity. Anthropometric measurements and blood sampling were done at the beginning and end of the study period. RESULTS: CQR-300 as well as CORE exhibited antioxidant properties in vitro. They also acted as in vivo antioxidants, bringing about significant (p < 0.001) reductions in plasma TBARS and carbonyls. Both CQR-300 and CORE also brought about significant reductions in weight, body fat, total cholesterol, LDL-cholesterol, triglycerides, and fasting blood glucose levels over the respective study periods. These changes were accompanied by a significant increase in HDL-cholesterol levels, plasma 5-HT, and creatinine. CONCLUSION: CQR-300 (300 mg daily) and CORE (1028 mg daily) brought about significant reductions in weight and blood glucose levels, while decreasing serum lipids thus improving cardiovascular risk factors. The increase in plasma 5-HT and creatinine for both groups hypothesizes a mechanism of controlling appetite and promoting the increase of lean muscle mass by Cissus quadrangularis, thereby supporting the clinical data for weight loss and improving cardiovascular health.
Language: eng
Unique Identifier:
MajorMeSH Heading: Cissus
MinorMeSH Heading Adult, Anti-Obesity Agents, Antioxidants, Body Weight, Double-Blind Method, Female, Flavonoids, Humans, Male, Middle Aged, Obesity, Overweight, Oxidative Stress, Phenols, Placebos, Plant Extracts, Reference Values,
--------------------------------------------------------------------------------
Publication Type: Controlled Clinical Trial
ISSN: 1476511X
Country of Publication: England
Google it on pubmed there are many studies on Cissus
Search Results from the National Library of Medicine and PubMed. Disclaimer Notice
New Search Save Article Save Query: cissus
Place in Cart Email Citation
Export selected citation in EndNoteRefManProCite Export
Title: The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome.
Author: Oben J , Kuate D , Agbor G , Momo C , Talla X
Source: Lipids Health Dis, 5(): 24 2006
Service Fee: $12.00 ; Copyright Royalties: $0.00
Abstract: AIM: Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. METHODS: The study was a randomized, double-blind, placebo-controlled design involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19-50). The 92 obese (BMI >30) participants were randomized into three groups; placebo, formulation/no diet, and formulation/diet (2100-2200 calories/day). The 31 overweight participants (BMI = 25-29) formed a fourth (no diet) treatment group. All participants received two daily doses of the formulation or placebo and remained on a normal or calorie-controlled diet for 8 weeks. RESULTS: At the end of the trial period, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein were observed in participants who received the formulation, regardless of diet. CONCLUSION: Cissus quadrangularis formulation appears to be useful in the management of weight loss and metabolic syndrome.
Language: eng
Unique Identifier:
MajorMeSH Heading: Diet, Reducing
MinorMeSH Heading Adult, Anti-Obesity Agents, Blood Glucose, Body Mass Index, Body Weight, Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Cissus, Diarrhea, Double-Blind Method, Female, Headache, Humans, Male, Metabolic Syndrome X, Middle Aged, Obesity, Overweight, Plant Extracts, Prospective Studies, Treatment Outcome, Triglycerides, Weight Loss,
--------------------------------------------------------------------------------
Publication Type: Journal Article
ISSN: 1476511X
Country of Publication: England
heres another(noting it decreases fatloss,improves health and lipid profile , cardiovasuclar function and builds muscle mass. one nice combo.
Search Results from the National Library of Medicine and PubMed. Disclaimer Notice
New Search Save Article Save Query: cissus
Place in Cart Email Citation
Export selected citation in EndNoteRefManProCite Export
Title: The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress.
Author: Oben JE , Enyegue DM , Fomekong GI , Soukontoua YB , Agbor GA
Source: Lipids Health Dis, 6(): 4 2007
Service Fee: $12.00 ; Copyright Royalties: $0.00
Abstract: AIM: Obesity is generally linked to complications in lipid metabolism and oxidative stress. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a proprietary formulation containing CQR-300 (CORE) on weight, blood lipids, and oxidative stress in overweight and obese people. METHODS: The first part of the study investigated the in vitro antioxidant properties of CQR-300 and CORE using 3 different methods, while the second part of the study was a double-blind placebo controlled design, involving initially 168 overweight and obese persons (38.7% males; 61.3% females; ages 19-54), of whom 153 completed the study. All participants received two daily doses of CQR-300, CORE, or placebo and were encouraged to maintain their normal levels of physical activity. Anthropometric measurements and blood sampling were done at the beginning and end of the study period. RESULTS: CQR-300 as well as CORE exhibited antioxidant properties in vitro. They also acted as in vivo antioxidants, bringing about significant (p < 0.001) reductions in plasma TBARS and carbonyls. Both CQR-300 and CORE also brought about significant reductions in weight, body fat, total cholesterol, LDL-cholesterol, triglycerides, and fasting blood glucose levels over the respective study periods. These changes were accompanied by a significant increase in HDL-cholesterol levels, plasma 5-HT, and creatinine. CONCLUSION: CQR-300 (300 mg daily) and CORE (1028 mg daily) brought about significant reductions in weight and blood glucose levels, while decreasing serum lipids thus improving cardiovascular risk factors. The increase in plasma 5-HT and creatinine for both groups hypothesizes a mechanism of controlling appetite and promoting the increase of lean muscle mass by Cissus quadrangularis, thereby supporting the clinical data for weight loss and improving cardiovascular health.
Language: eng
Unique Identifier:
MajorMeSH Heading: Cissus
MinorMeSH Heading Adult, Anti-Obesity Agents, Antioxidants, Body Weight, Double-Blind Method, Female, Flavonoids, Humans, Male, Middle Aged, Obesity, Overweight, Oxidative Stress, Phenols, Placebos, Plant Extracts, Reference Values,
--------------------------------------------------------------------------------
Publication Type: Controlled Clinical Trial
ISSN: 1476511X
Country of Publication: England
Google it on pubmed there are many studies on Cissus