So I sent a link to an interesting study and article today so I thought I would post it up.
Plus it fits in well with the log I will be starting this Saturday AlphaMass/5 AlphaTest :thumbsup:
1-DHEA - Powerful Prohormone According to Researchers | Designer Steroids | TunedSports.com - Legal Anabolic Steroid & Pro-hormone Supplement Blog.1-DHEA – Powerful According to Researchers
1-DHEA is a prohormone to 1-Testosterone (dihydroboldenone). It is commonly sold under the brand name of “1-Andro” (1-Androsterone). 1-Andro is a non 17-aa prohormone requiring two steps in its conversion to 1-Test. Reduction of the 17-ketone functional group by 17b-HSD produces 1-Androstendiol while oxidation of the 3-hydroxyl group by 3b-HSD produces 1-Androstenedione. Both of these metabolites may have some intrinsic anabolic/androgenic properties, but it is their further conversion to 1-Testosterone that produces the anabolic muscle building effects seen from 1-Andro.
http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1552&context=ijesab3-hydroxy-5alpha-androst-1-en-17-one Enhances Muscular Gains but Impairs the Cardio-metabolic Health of Resistance Trained Males.
Anabolic steroids increase resistance training (RT) gains (muscle strength and hypertrophy) but are illegal
to purchase. Prohormone supplements are purported to offer similar benefits but research on the efficacy
and side effects of these supplements is scarce. Purpose: To assess the efficacy and side effects of a popular
prohormone supplement in resistance-trained males. Methods: 16 males (23±1yrs; 13.1±1.5%BF; 5.3±1.0yrs
RT experience) were randomly assigned to ingest either 330 mg/d 3-hydroxy-5alpha-androst-1-en-17-one
(PROHORMONE; n=9) or 330 mg/d sugar (PLACEBO; n=7) while completing a 4 week (16 session)
structured RT program. Data collection was double-blind. Body composition (lean mass:
hydrodensitometry), muscular strength (total load (kg) on 1 repetition maximum of
bench/squat/deadlift), circulating lipids (cholesterol, HDL-C, LDL-C), cardio-metabolic function
(creatinine, serum glutamic oxaloacetic transaminase (SGOT), circulating cytokines (TNF-a, Il-6, Il-10) and
psychological factors (anger: State/Trait Anger Expression Inventory/ anxiety: Hospital Anxiety &
Depression Scale/ fatigue: Fatigue Impact Scale/ mood: Profile of Mood States) were assessed at the
beginning and end of the supplementation period. A 2-factor [Time*Condition] repeated measures
ANOVA was used to discern differences between groups. Results: Increases in lean mass (4.7±0.9 VS.
0.5±0.6 kg; p=0.013) and muscular strength (73.2±5.8 VS. 31.4.1± 8.6 kg; p=0.008) were greater in
PROHORMONE than PLACEBO. However, creatinine (1.06±0.03 to 1.27±0.04 mg/dl; p=0.033), SGOT
(24.8±0.9 to 41.4±6.3 IU/L; p=0.008), LDL-C/HDL-C (2.2±0.2 to 4.8±0.6; p=0.008), and Cholesterol/HDL-C
(3.6±0.3 to 6.4±0.6; p=0.003) increased and HDL-C (46.1±3.5 to 27.3±1.3 mg/dl; p=0.018) decreased from
pre-posttest in PROHORMONE; these variables were unchanged in PLACEBO. None of the circulating
cytokines nor any of the psychological factors changed from pre-posttest in either group. Conclusion: The
prohormone supplement contributed to robust improvements in muscle mass and strength in resistancetrained males but these gains came at the price of subject’s cardio-metabolic function
Plus it fits in well with the log I will be starting this Saturday AlphaMass/5 AlphaTest :thumbsup: