I have seen some mechanisms for this - I am impressed you pulled that up. I feel like it is a long-term appetite modifier, not an acute suppressant though. In other words, if you take it today, you will probably still be hungry with maybe a very minor reduction in appetite, but if you take it consistently for 6 months, it can improve your metabolic profile in a way that you will slowly eat more normally without realizing it.
I have been extremely obese and I am convinced I messed my hunger signals up pretty good from this. I've researched a bunch of natural compounds to correct this lont-term and tested them. Cissus is definately on my list from that angle.
My "Off Switch" for eating is very poor. Actually, even after I lost significant weight, I could eat and NEVER feel full. It was pretty amazing. People had a hard time believing it. One holiday season from Thanksgiving to New Years I put on 25 pounds, no joke. I just didn't have any signal to stop eating. I would say I have 4-5 compounds I've tried, some of which people would laugh at if I recommended them on here, that have corrected this and Vitamin D and Cissus are 2 of them. The others...kind of want to keep to myself for a while
Most people look for short-term, accute effects though, so I am not sure a product that you have to take for 6 months before you see any effects will have much market (and even then the effects may be unconscious if you're not being meticulous in paying attention).