I may be late because the study below was posted on Mar 17:
ncbi.nlm.nih.gov/
pmc/articles/PMC5566634/#!po=27.4194
I don’t think the higher MTOR signaling urolithin B made vs insulin would make a significant difference. Especially considering insulin makes it’s incursion multiple times a day through out our bodies. The cells were also incubated with rapamaycin which is an inhibitor of the MTOR pathway. A normal weight lifting person is not taking this stuff everyday. So our MTOR pathway is by no means already down graded, it’s being used more often than not. The insulin and UB probably caused some rebound effect.
In the hyper trophy study, mice gained muscle weight in 4 weeks but lost testicular weight. But plasma test lvls weren’t impacted.
Ellagitannins (ETs) and ellagic acid (EA) are polyphenols present in some fruits, nuts and seeds, such as pomegranates, black raspberries, raspberries, strawberries, walnuts and almonds. ETs are hydrolyzed to EA under physiological conditions in vivo and EA is then gradually metabolized by the intestinal microbiota to produce different types of urolithins.
ncbi.nlm.nih.gov/
pmc/articles/PMC5566634/#!po=27.4194
I don’t think the higher MTOR signaling urolithin B made vs insulin would make a significant difference. Especially considering insulin makes it’s incursion multiple times a day through out our bodies. The cells were also incubated with rapamaycin which is an inhibitor of the MTOR pathway. A normal weight lifting person is not taking this stuff everyday. So our MTOR pathway is by no means already down graded, it’s being used more often than not. The insulin and UB probably caused some rebound effect.
In the hyper trophy study, mice gained muscle weight in 4 weeks but lost testicular weight. But plasma test lvls weren’t impacted.
Ellagitannins (ETs) and ellagic acid (EA) are polyphenols present in some fruits, nuts and seeds, such as pomegranates, black raspberries, raspberries, strawberries, walnuts and almonds. ETs are hydrolyzed to EA under physiological conditions in vivo and EA is then gradually metabolized by the intestinal microbiota to produce different types of urolithins.