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Zantac and Gyno?!

  1.  04-24-2003  10:51 AM
    Gold Member jweave23's Avatar
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    Zantac and Gyno?!


    From fizler over at BB.com: he said he has gyno and has been taking Zantac for 4 years now, seems odd to me also. Here are some links he provided:

    http://www.gastrosite.com/physician/zantac/za615saf.htm

    http://www.rxlist.com/cgi/generic/ranit_ad.htm

    Anyone know why rantidine would cause this?



  2.  04-24-2003  11:17 AM
    Registered User Jay Mc's Avatar
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    However, occasional cases of gynecomastia, impotence, and loss of libido have been reported in male patients receiving ranitidine HCl, but the incidence did not differ from that in the general population.
    Sounds to me like he was just doomed to get it. According to that link the drug DOES NOT cause gyno at an increased rate. I don't see how an H2 recepotor antagonist would have any effect on estrogen levels or gyno...that one link even says it has no neurosecretory properties...Its all about Occam's razor...why look for a contrived explanation when a more likely obvious one is available...

    J

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  3.  04-24-2003  11:23 AM
    Registered User scotty2's Avatar
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    I would think one would have to be genetically predisposed to gyno. Or, would already have a mild case. I don't see where the use of this substance could cause gyno without those pre-existing conditions.

  4.  04-24-2003  12:31 PM
    Registered User Sheesh's Avatar
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    There is no way it could've caused it IMHO...

    From the first link
    Incidence of gynecomastia, impotence, and loss of libido does not differ from that in the general population
    From the second link...

    However, occasional cases of gynecomastia, impotence, and loss of libido have been reported in male patients receiving ranitidine HCl, but the incidence did not differ from that in the general population.
    Both of these say that it DOESN'T have anything to do with gynecomastia. That guy over at BB.com needs to learn how to read the fine print...

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