Androgens common in obese teenage girls

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    Post Androgens common in obese teenage girls


    Androgens common in obese teenage girls

    Charlottesville (Virginia) - Girls who are obese during the early stages of puberty have an increased risk of developing abnormally high levels of androgens, a type of steroid hormone, according to a report in The Journal of Clinical Endocrinology & Metabolism.

    This condition, referred to as hyperandrogenemia, is characterised by high levels of androgens, such as testosterone or androsterone, hormones that control the development masculine characteristics.

    Hyperandrogenemia is also associated with the later development of polycystic ovarian syndrome, a condition that includes infertility, obesity, abnormal menstrual cycles and excessive hair growth.

    "I would be pleased if these findings contribute to an increased awareness that hyperandrogenemia may be more common in obese children and adolescents, and that relative hyperandrogenemia may be present very early on (ie even before clinical puberty is evident)," Dr Christopher McCartney from the University of Virginia Health System, Charlottesville, said.

    McCartney and colleagues evaluated the relationship between weight, hormonal measurements and pubertal stage in 76 girls aged seven to 17 years. Forty-one of the girls were classified as obese.

    Total testosterone levels were 2,1 times higher, sex-hormone binding globulin 50 percent lower, and free testosterone three times higher in obese girls than in normal-weight girls, the team reports.

    The associations were similar, but less marked, when girls with excessive facial hair growth (hirsutism) or irregular menstrual periods were excluded from the analysis.

    Obesity was also associated with higher testosterone and lower sex-hormone binding globulin levels when considering only girls earlier in puberty, the results indicate, even when girls with hirsutism were excluded.

    Most doctors know that childhood obesity is associated with abnormal glucose metabolism, high blood pressure and cholesterol problems, and all conditions the increase the future risk of cardiovascular disease, McCartney said.

    "However, it seems less well appreciated that obesity may be associated with cosmetic problems (eg, hirsutism) in the near-term and may have implications for future fertility."

    He said it is important for obese adolescent girls and their parents to be aware of these potential risks. - Reuters

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    I got a good laugh when I was reading my notes one day. I think it was nutrition class (I'm in PA school). Stated that excess body fat releases small amounts of testosterone. People often think of fat as just a blob, but fat has vasculature and can even secrete hormones. Anyway I laughed in class picturing some of the "bigger" girls I'm known and some did seem awfully masculine!!!
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    C'mon, who hasn't seen a fat-chick with a "stache"? They're also usually the ones that threaten to beat you up and can pick you up and squash you like a grape
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    So can we get a source of exogenous test by dating large girls? Is that what you are saying? lol


    I think I have read that excess estrogen also is secreted by large amounts of adipose tissue which, of course, makes it even harder to lose weight.
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    Quote Originally Posted by bioman
    I think I have read that excess estrogen also is secreted by large amounts of adipose tissue which, of course, makes it even harder to lose weight.
    This is indeed true for men, as aromatase thrives in adipose tissue.
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    Now if we could only extract all that test out of these fat girls. It's like a limitless supply right under our noses. Some sort of test donation center where we give them a few bucks.
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    Quote Originally Posted by bioman
    Now if we could only extract all that test out of these fat girls. It's like a limitless supply right under our noses. Some sort of test donation center where we give them a few bucks.
    This is called androgel.
  

  
 

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