The Official Hypothyroidism Thread

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  1. I have honestly just given up on fat loss. I lift, been doing 5/3/1 with really good results, and spin for about 40min 4 times a week and eat pretty clean. I figure when it is meant to be it will happen


  2. Hey everyone...so I'm not sure if this forum is still in use, but I will try anyways. Here's my story...

    My name is Amy, I'm 25, im 5'10" and about 245 pounds. I've always been a little over weight, but I dont look awful since im so tall. And when I have the energy and time to, I have been able to lose weight. So for the past 4 or 5 months I have been feeling like hell...I've never had a migraine in my life, but have had them constantly for the last 4 months. I am nauseous, dizzy, numb and tingly down the right side of my body, no energy, extremely moody, loosing hair, gaining a little weight but not too much, very absent minded, forgetting A LOT!! So my doctors did every test imaginable...except a blood test. My brain MRI came back with some "non-specific white matter" in my frontal lobes (whatever that means). So right now I am waiting to see my neurolgist and figure out a treatment plan. Well when I was at my Dr. Last thursday I suggested we should do a CBC since I hadnt had one done in about 2 years. So I had some blood drawn, and she called me Friday morning. My TSH was off the charts. A 43. She couldn't believe it. She said it explains almost all of my symptoms except the headaches. So I am still dealing with that. She called in a script of Synthroid to my pharmacy and I picked it up after work and started my frist dose sat morning. I still am not seeing any results in my energy levels, but im pretty used to being tired all the time.

    About a year ago I was doing Hot Yoga 6 days a week and going to the gym twice a day, 6 days a weeks for about 2 months and I lost about 30 pounds. Im not exactly sure when my Thyroid started to give...but I am going to try to lose weight again, hopefully successfully. I guess my question is, does anyone have any tips and diet and exercise? My diet has been awful. I have started a new job and am working from 7am to 6pm, so I dont really eat meals, just kind of snack here and there.

    They also have me on all sorts of meds. Topamax for the migraines, Synthroid for the Thyroid, Percocet for my back (6 bulging disks from a car accident), Ambien CR for sleep...and I think thats it...I can't remember Anyway...any help would be GREATLY appreciated!!!!

    Thanks!!
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  3. GREAT thread. I'm a fellow hypothyroid lifter, diagnosed a year ago.

    I'll be along for the ride if this picks up again.

    AmyKat, that is quite a story, at the least you will want to get off those narcotics. The average MD won't give you any alternatives, but if you find a good doc they will prescribe you massage therapy which can have enormous effects on your pain and healing process from the car accident/bulging disks. Definitely something to look into. Although, that post was from 3/4 a year ago... I hope you are doing better!

    MidwestBeast, if you don't mind me asking, how has your condition progressed?
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.
  4. AnabolicMinds Site Rep
    MidwestBeast's Avatar

    Quote Originally Posted by rambofireball View Post
    MidwestBeast, if you don't mind me asking, how has your condition progressed?
    No success in finding the cause(s) or solution, yet. I just met with an endocrinologist (pituitary and thyroid specialist) at Vanderbilt, last week. She is checking cortisol as the problem again (by 2 midnight salivary tests and a 24-hour urine test). If either or both of those come back suspect, it will be the dexamethasone suppression test and that will tell if it's Cushing's or not.

    She said I'd effectively ruled out the thyroid as a problem in all of this by all the testing and experimenting I'd done and that it was just something I'm dealing with, but not a cause. The disappointing thing was when she said if it's not cortisol, then there's (in her mind) nothing else to check/do and she mentioned I should consider prescription weight-loss drugs (phentermine, etc. and even metformin). I proposed the chance it's a DNA mutation/flaw or a problem at a cellular level (mitochondrial issue, perhaps-->energy expenditure issue). She said even if it was, there was nothing to do to fix those problems.

    These last 2+ years have sucked, and as tired as I am, I refuse to give up or believe this can't be fixed. So, saliva tests just got mailed back today (she said the lab would take 3-4 weeks to process them) and I'll do the urine testing next week, most likely (not in as much of a rush since it'll still get done before the saliva results come in). I'm not getting ahead of myself. I'll see if cortisol is an issue and if not, I'll go from there. If it means going to Mayo, I'll do that.

  5. Wow, that does sound rough. I can kinda commiserate. In 2003, I had a full body CAT scan when was unconscious in the ER after being hit by a car, and when I woke up they told me I had all these broken bones and a concusion and what not, "..and, oh, we also found a pituitary tumor" lol. The tumor has had a lot of fun with wreaking havoc on my endocrine system for most of my life, and stopped responding to the expensive meds a couple years ago, so I had the doc crack me open and take it out last September. My hormones never stabilized as promised so I'm back on quite a bit of HRT and the tumor is back! The damn thing still isn't responding to the meds, persistent little f*ck. Lol, when life gives you lemons..

    It is inspiring to hear that you are driven to find the cause and solution. A lot of people just give up when they have come as far as you have.

    Best of luck with the forward progress.
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.
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  6. AnabolicMinds Site Rep
    MidwestBeast's Avatar

    Quote Originally Posted by rambofireball View Post
    Wow, that does sound rough. I can kinda commiserate. In 2003, I had a full body CAT scan when was unconscious in the ER after being hit by a car, and when I woke up they told me I had all these broken bones and a concusion and what not, "..and, oh, we also found a pituitary tumor" lol. The tumor has had a lot of fun with wreaking havoc on my endocrine system for most of my life, and stopped responding to the expensive meds a couple years ago, so I had the doc crack me open and take it out last September. My hormones never stabilized as promised so I'm back on quite a bit of HRT and the tumor is back! The damn thing still isn't responding to the meds, persistent little f*ck. Lol, when life gives you lemons..

    It is inspiring to hear that you are driven to find the cause and solution. A lot of people just give up when they have come as far as you have.

    Best of luck with the forward progress.
    That's rough, man. I definitely respect your drive in all of this, too.

    I'd be lying if I said I hadn't thought about giving up, but I also know who I am and fitness/health/nutrition is such a huge part of my life that even though these couple years have been downright miserable, I have to fight through it. I'm a big believer in that God has a plan and that it will make sense, eventually. I've felt that way for practically my whole life, but this is the first time I've really been tested. That just goes to show how lucky I've been and how awesome my life has been. This all sucks, but through all of it, I've never lost faith that there's a reason for this and that it'll one day make sense. I just hope that I'm closer to finding that out and getting this resolved.

    If you ever want/need to chat, just hit me up, man.

  7. Quote Originally Posted by MidwestBeast View Post
    That's rough, man. I definitely respect your drive in all of this, too.

    I'd be lying if I said I hadn't thought about giving up, but I also know who I am and fitness/health/nutrition is such a huge part of my life that even though these couple years have been downright miserable, I have to fight through it. I'm a big believer in that God has a plan and that it will make sense, eventually. I've felt that way for practically my whole life, but this is the first time I've really been tested. That just goes to show how lucky I've been and how awesome my life has been. This all sucks, but through all of it, I've never lost faith that there's a reason for this and that it'll one day make sense. I just hope that I'm closer to finding that out and getting this resolved.

    If you ever want/need to chat, just hit me up, man.
    Damn, good luck man. And I agree, there is always a reason, spiritual and physiological. And if there is a cause, there is a solution. I once read a story about a carpenter whose wife had fallen ill with some sort of chronic disease that there was no cure for. The guy had no scientific know-how when she was first diagnosed, and the doctors told him it was more a matter of prolonging life and making her comfortable than it was beating the illness. Well, some amount of time later and after a whole lot of reading the guy eventually found a way to save his wife. I can't remember what the illness was or when it was, but I think the dude was Italian? Anyway, it's stories like that which can really help you push through the feelings of hopelessness.

    There is a solution. If you persevere, you will find it.
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.

  8. hey guys ive been reading through this thread and have learned a lot. i recently found out that i may be having issues w my thyroid. im getting more bloodwork done soon and have endocrine appointment next month. i was told thyroid seems slow but the free hormone levels were not effected. also, i have "high prolactin" levels. i was screened for a tumor which came back negative. anyone have any experience w this?
  9. AnabolicMinds Site Rep
    MidwestBeast's Avatar

    Quote Originally Posted by GIJane1928 View Post
    hey guys ive been reading through this thread and have learned a lot. i recently found out that i may be having issues w my thyroid. im getting more bloodwork done soon and have endocrine appointment next month. i was told thyroid seems slow but the free hormone levels were not effected. also, i have "high prolactin" levels. i was screened for a tumor which came back negative. anyone have any experience w this?
    Prolactin can vary a bit between men and women (depending on her age; whether it's around pregnancy; etc.). I did in fact have elevated prolactin levels and had a dynamic brain MRI done to specifically look at the pituitary and no prolactinomas/adenomas (small tumors) were found. However, they did point out that there are micro-prolactinomas and there's a possibility in those cases that a tumor does exist, but it just can't be seen.

    I'd say it depends on your situation and what your prolactin levels are as far as how you go about treating it.

    If you've got copies of any of your blood work, feel free to post the results and I'd be happy to interpret them (just know I'm not the greatest at it; I just have 2+ years of experience digging through/researching all this stuff).

    If you had an elevated TSH, I'd check TPO-Ab and Tg-Ab to rule out or confirm Hashimoto's, since it's the number one cause of hypothyroidism (in the US, at least) and is far more predominant in women (this is what I have).

  10. thank you. i will try to post new results in 2 wks when they run the bloodwork again. i'm 32 y/o female and definately not pregnant. the dr is trying to determine if my thyroid tested slow due to supps i was on so they are really looking at results this time around. hypothyroidism does run in my family though. i was told poor thyroid function can elevate prolactin levels. i guess im concerned about effects of elevated prolactin, as i dont have common side effects of women such as fluid leakage.
  11. AnabolicMinds Site Rep
    MidwestBeast's Avatar

    Quote Originally Posted by GIJane1928 View Post
    thank you. i will try to post new results in 2 wks when they run the bloodwork again. i'm 32 y/o female and definately not pregnant. the dr is trying to determine if my thyroid tested slow due to supps i was on so they are really looking at results this time around. hypothyroidism does run in my family though. i was told poor thyroid function can elevate prolactin levels. i guess im concerned about effects of elevated prolactin, as i dont have common side effects of women such as fluid leakage.
    It really depends how high the prolactin is/was. Mine was at 17 at its highest (measured) with a ref. range of 3-13 for males. I didn't have any lactation or anything like that, but I was concerned with the long-term effect on decreasing fertility.

    TSH is a pituitary hormone, so it can make sense for prolactin to go up, as it is, as well.
  12. T4 CRASH


    Just started T4 @ 50mcg/day in a.m. after a second FT4 reading came in even lower @ 0.56 (ref range 0.82-1.77) than from the June reading. It's never been this low. At first, I believed it to be from taking T3, but now my hunch is it's from eating VLC paleo/keto as I adjust my calories (need more from fat to make up loss from carbs!) - or perhaps both. FT3 was also slightly low (I have been on 100 mcg T3 [75mcg sustained-release T3 + 25mcg Cynomel]). Another possibility: carnitine supplementation.

    I am on day 4 and am just now starting to crash with evening fatigue, wanting to lie down against my will. If I resist the fatigue, I "un-crash and reset" in about an hour.

    Is this a normal "adjustment" reaction, as I did not notice this from when starting T3?
    Should I try cutting the dose in half to 25mcg (this is why my doc doesn't always advocate natural thyroid like Armour, as you can't adjust the T3 or T4)?
    I have never tried T4 before and thought this was a prime time to give it a shot and see. My biggest fear was that T4 would shunt to start boosting my rT3 levels which is why we stuck with T3 only.

    Other relevant readings:
    - rT3 was @14.7 (ref range 13.5-34.2)
    - TSH @1.63.
    - preg is low @ 43 (I cannot tolerate oral preg any longer). I will be trying Dr. John's OTC TD preg cream.
    - a.m. serum cortisol is 12.7 (am waiting to get my 4x's saliva cort in)
    - homocysteine increased from 7 to 9.2 despite my heavy methylation support for my MTHFR C677T genetic mutation
    - TPO AB and TgAb are both low normal
    - SHBG is elevated @61.4 (my guess: from taking T3)
    - Prog is high normal @ 1.4
    - E2 is low normal @ 8
    - Lipid profiles have improved significantly from June labs which I will report on separately
    - Plasma Renin Activity & Aldosterone is LOW @ 0.55 (ref range 1.31-3.95) and Aldosterone is also low @ 3.4 (ref range 0.0-30.0) though my BP runs high, not low.
  13. AnabolicMinds Site Rep
    MidwestBeast's Avatar

    A few thoughts:

    I was initially sucked into the Wilson's syndrome/rT3 wormhole and was concerned that it was hurting my conversion to T3, thus, hindering me. What I've learned through further research is that it's pretty much garbage. Reverse T3 is a stress indicator; it's elevated when there's something else going wrong, so the whole T3-only supplementation at a high dose to "clear" rT3 isn't necessary at all. I did the same thing and it also drove my FT4 levels into the ground. No idea bout the carnitine or your diet, but that's likely the number one culprit for your FT4 being low OOR.

    As far as a crash, I don't think that's something that the Synthroid/T4 should be causing. The half-life of it is very long and it will build up in your blood stream over time (that's why they don't recommend blood work until 6 weeks after being on that dose). 50mcg is actually the general starting dose and very low (I'm on 137mcg right now and some go even higher), so I wouldn't be concerned about halving it.

    Cortisol/ACTH would be interesting to look into further with the low aldosterone levels. I actually have a doc that wanted to check that one last time for me and she had me do a 24-hour urine collection for cortisol, again, but made me drink minimal fluids to keep total urine volume down (it was 6 liters last time and this time was maybe 1.5) because the high urine content can keep the cortisol circulating instead of being reabsorbed by the kidneys. She also had me do 2 midnight saliva cortisol tests and said the daytime saliva tests aren't that important.

    Anyway, I hope that helps some.

  14. can someone give me cliffs, or a link, about why and how hypothyroidism works and how it can beat math? Ive heard of people having this condition but it never made sense to me since cals in vs cals out is complete mathematics.... id like to understand what you guys go through as my mom says she has this but i never understood
  15. AnabolicMinds Site Rep
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    Quote Originally Posted by y0lked View Post
    can someone give me cliffs, or a link, about why and how hypothyroidism works and how it can beat math? Ive heard of people having this condition but it never made sense to me since cals in vs cals out is complete mathematics.... id like to understand what you guys go through as my mom says she has this but i never understood
    Well, essentially, you're right. Hypothyroidism results in a slower metabolism that decreasing cals or upping exercise should take care of. I would assume that more often than not, people with hypothyroidism have other accompanying issues that make it more difficult. I'm still not sure what all I'm dealing with, but it's more than just hypothyroidism.

    So to answer your question, in my opinion, it isn't the hypothyroidism that defies science, but something else at play (and then the hypothyroidism obviously doesn't help things).

  16. Has anyone mentioned anything about fluoride in this?
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  17. not that i read. care to elaborate?

  18. So - the questions remains - based on my deficient FT4 levels, should I add T4 or not? Assuming I have a conversion block, we can assume T4 will shunt to rT3 - the exact opposite of the goal of the T3 monotherapy (which was to suppress TSH and rT3 levels) which we have accomplished to a degree. Since T4 is a storage hormone whose job is to convert (in euthyroid individuals) to T3, does it even have any metabolic significance itself? Does it really matter if my FT4 levels are depressed?

  19. heard back from dr. thyroid hormones now test normal but prolactin still elevated. the only side i experience from this is low libido. any other possible causes?

  20. Quote Originally Posted by GIJane1928 View Post
    heard back from dr. thyroid hormones now test normal but prolactin still elevated. the only side i experience from this is low libido. any other possible causes?
    Has the doc talked to you about the possibility of a prolactinoma? This is the main cause of prolactiaemia (high prolactin), a tumor of the anterior lobe of the pituitary gland which is an overgrowth of lactotroph cells that secrete prolactin. There are currently only two treatments accepted as valid in the medical community; dopamine receptor agonist therapy (cabergoline or bromocryptine, preferably cabergoline) which mimics the inhibitive properties of dopamine on prolactin secretion in order to cause cell shrinkage and prolactin secretion decline, or transphenoidal adenectomy - a surgery in which the tumor is removed. Usually people start with cabergoline and go to surgery if they are non-responsive to the cabergoline, which is not very often as cabergoline has a high success rate.

    As far as other treatment methods, when studies are done on prolactinomas, the researchers usually inject the test rats with a mega dose of estradiol to instigate tumor formation. Because of this connection prolactinaemia to high levels of estrogen, some docs have started using aromatase inhibitors to lower estrogen and subsequently prolactin. This may not be the best mode of treatment for you as you are female, but it may be worth it to get a lab of your e2 (estradiol).

    Also, I've been following a study in Iran which is currently underway investigating the effectiveness of Curcumin from Turmeric extract as a viable treatment for clinical prolactinaemia in humans. It was scheduled to have already been finished, but the results have not been posted/published yet. There have been several studies done in rats showing promise for treatment of prolactinaemia, but none in humans that I am aware of besides the above.
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.

  21. I just read above that you have already had an MRI showing no macroadenoma (big tumor), but as beast said above, it is entirely possible you have a microadenoma (small tumor), which is much easier to deal with.
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.

  22. i go to see the endocrinologist in a week or so. i will ask about a smaller mass that may not have been seen. any supps that i could have taken that could play w prolactin?

  23. Of the top of my head D-Aspartic Acid and Agmatine can both raise prolactin. I'm sure there are many more. Do you have a list of what you have been on?
    My parents created my body, in which I create my mind. I will honor them, by developing both to their utmost potential.

  24. currently: womens multivit, half a dexaprine a day (new version) vitamin C and D, tyrosine, calcium, magnesium, glucosamine, green tea extract, trib test, zma, l carnatine and kelp

    in the past: l-dopa, abliderate advanced, lean xtreme
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