Trying to Upregulate Beta Receptors
- 02-08-2011, 09:22 AM
Trying to Upregulate Beta Receptors
Had a great two weeks of Clen. Only dropped a few pounds on the scale (about 4 lbs, from 202 to 198), but thatís OK since Iím doing a gradual cut. Most importantly, Iím firming up in the waistline, and seeing 4 abs plus delt striations. Strength has not dropped at all, and is actually up a bit in some exercises. Basically just eating all whole foods, and running about 2400-2700 cals a day. Dropped most all of the protein drinks and getting most of the pro from chicken, fish, and meat
Anyway, Iím taking a week break in the Clen, in an effort to re-up my Beta Receptors. I donít have any Ketotifen, so Iím trying 25-50 mg of Benadryl before bed. So a 1 week break from Clen and some anti-histamine therapy, so that next week, I can get some shakes from 20 mcg again.
My question is this:
Will I still up-reg Beta receptors if I take Yohimbe, Geranium Stem or other popular thermogenic herbs in my ďoff weekĒ from Clen? Or do they have a similar (downregulating) effect on Beta Receptors, like Clen or Ephedrine do?
Thanks in advance, my bruthas!
- 02-14-2011, 03:44 PM
Well, I took a week off Clenbuterol, and took 25-50 mg Benadryl every night.
I did take some OEP and Yohimbe last week. I read somewhere that Yohimbe acts on alpha receptors, so I figured it would not hit my (already hurting) Beta Receptors. I got effect off the Yohimbe - jittery, you know?
So today I go back down to 40 mcg Clen, and guess what - I got the warm feeling back, and some mild hand shakes (which I actually like - lets you know its working). Also, I sweated like a pig doing a variety of deadlifts, hams, and Cardio today
Don't know if it was the 1 week break, or the 1 week break plus Benadryl that did the trick for me. Patrick Arnold does not put faith in Benadryl for cleaning Beta Receptors. Said it is nothing like Ketotifen, pharmacologically. But it is way cheaper! I think my sinuses were so "anti-histamined up" that it made my nose run excessively.
Any similar experiences with Clen cleaning?
02-21-2011, 07:39 AM
02-26-2011, 12:50 PM
02-26-2011, 03:38 PM
02-28-2011, 09:04 AM
I am curious about other anti-histamines.
Is this beta receptor cleaning helped out by other OTC antihistamines? I am convinced that Benadryl helps.
02-28-2011, 03:40 PM
02-28-2011, 04:08 PM
Why Benadryl? Why not just take a two week break? I don't understand why take Benadryl if you aren't running straight thru.
02-28-2011, 10:21 PM
03-07-2011, 02:40 PM
Why Benadryl you ask? Well, like everything else around here, you give it a try and see if it works. Benadryl is cheap as nuts, and it help you sleep too. Thinking out loud, I'm not sure what the downside is (like does Bendryl hit the Kidneys, Liver, or something like that?) Not sure.
But as I found through self experimentation, 1 week off Clen w/ 50 mg Benadryl nightly (after 3 weeks on Clen to 80 mcg), and I was able to go back to 40 mcg, after only one week off, and get the effects at a reasonably low dose.
By the way, I'm doing a two week break in Clen this time. With Benadryl
06-09-2015, 01:43 PM
06-09-2015, 05:29 PM
Why don't you buy some Ketotifen from a chem site? Keto works wonders for up-regulating your receptors, and you'll sleep like a baby
06-09-2015, 09:42 PM
06-09-2015, 09:46 PM
06-09-2015, 09:49 PM
06-10-2015, 02:16 AM
06-10-2015, 03:56 AM
06-10-2015, 06:19 AM
06-12-2015, 12:16 AM
Also, if you are going to Zambia..ditch the benadryl, apparently it's illegal there.
12-02-2015, 12:45 PM
Metals play a role..minerals...magnesium and Zinc can UR beta-adrenergic receptors..though magnesium decreases net norepinephrine levels..so only in coordination with *certain* stims it yields these benefits..but mag has other benefits like anti-cortisol and neuroprotection etc...!
12-02-2015, 01:21 PM
02-08-2016, 12:27 PM
04-23-2016, 04:28 PM
04-23-2016, 04:32 PM
The above is a good read, as it goes into not just how the receptors become desensitized (unable to respond to agonists like albuterol or lessened at least, even in response to natural adrenaline/epinephrine), and downregulated (decreased in number), but also the exact mediators and this gives insight, further, into possible methods to reverse the reduction in function of beta-receptors.
04-29-2016, 12:21 AM
04-29-2016, 06:01 AM
I'm still very confused as to whether or not it's ok to take oral DHEA because of its supposed suppression etc. I personally would love to take it daily at a dose of 50 mg daily. I'm 30 yrs old but every single time I do some research it's 50 percent saying it's ok to take and 50 percent saying it's not a good idea. It's frustrating
04-29-2016, 06:28 AM
That one guy's link above has a pretty good blog. I've been looking over it and can't find a lot of things I would disagree with. It's also rare to see anyone knowledgeable of the Pauling protocol for vessel repair, but he has an entry about that too. (unrelated - sorry for the hijack!)
"...The sole test of the validity of any idea is experiment." - Feynman
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