Trying to Upregulate Beta Receptors

  1. Post Trying to Upregulate Beta Receptors


    Had a great two weeks of Clen. Only dropped a few pounds on the scale (about 4 lbs, from 202 to 198), but thatís OK since Iím doing a gradual cut. Most importantly, Iím firming up in the waistline, and seeing 4 abs plus delt striations. Strength has not dropped at all, and is actually up a bit in some exercises. Basically just eating all whole foods, and running about 2400-2700 cals a day. Dropped most all of the protein drinks and getting most of the pro from chicken, fish, and meat
    Anyway, Iím taking a week break in the Clen, in an effort to re-up my Beta Receptors. I donít have any Ketotifen, so Iím trying 25-50 mg of Benadryl before bed. So a 1 week break from Clen and some anti-histamine therapy, so that next week, I can get some shakes from 20 mcg again.

    My question is this:
    Will I still up-reg Beta receptors if I take Yohimbe, Geranium Stem or other popular thermogenic herbs in my ďoff weekĒ from Clen? Or do they have a similar (downregulating) effect on Beta Receptors, like Clen or Ephedrine do?
    Thanks in advance, my bruthas!


  2. Well, I took a week off Clenbuterol, and took 25-50 mg Benadryl every night.
    I did take some OEP and Yohimbe last week. I read somewhere that Yohimbe acts on alpha receptors, so I figured it would not hit my (already hurting) Beta Receptors. I got effect off the Yohimbe - jittery, you know?

    So today I go back down to 40 mcg Clen, and guess what - I got the warm feeling back, and some mild hand shakes (which I actually like - lets you know its working). Also, I sweated like a pig doing a variety of deadlifts, hams, and Cardio today

    Don't know if it was the 1 week break, or the 1 week break plus Benadryl that did the trick for me. Patrick Arnold does not put faith in Benadryl for cleaning Beta Receptors. Said it is nothing like Ketotifen, pharmacologically. But it is way cheaper! I think my sinuses were so "anti-histamined up" that it made my nose run excessively.

    Any similar experiences with Clen cleaning?

  3. Dnp upregulates receptors while burning fat.
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  4. Quote Originally Posted by vein5 View Post
    Dnp upregulates receptors while burning fat.
    nice
    The difference between who you are and who you want to be is what you do.

  5. Quote Originally Posted by vein5 View Post
    Dnp upregulates receptors while burning fat.

  6. I am curious about other anti-histamines.

    Is this beta receptor cleaning helped out by other OTC antihistamines? I am convinced that Benadryl helps.

  7. Has anyone used the ketotifen eye drops? Those are OTC, I can't find tablets anywhere.

  8. Why Benadryl? Why not just take a two week break? I don't understand why take Benadryl if you aren't running straight thru.

  9. Quote Originally Posted by Magg0078 View Post
    Why Benadryl? Why not just take a two week break? I don't understand why take Benadryl if you aren't running straight thru.
    I've heard by people who use it say 3-4 weeks is the sweet spot to obtain max fat loss, unfortunately around the 2 week point is when receptors are down regulated, so the theory is that Diphenhydramine in Benadryl upregulates the receptors (even Benadryl is questionable, most say ketotifen is the way to go) to allow the longer cycle to obtain maximize fat loss. I've been told taking 2 weeks off isn't enough time to up regulate receptors without any meds. Half life of the clen is about 34-38 hours, a saturated body will still have clen in the system for about 1 week, only giving the body just about 1week to bounce back, which IMO isn't enough time.

  10. Why Benadryl you ask? Well, like everything else around here, you give it a try and see if it works. Benadryl is cheap as nuts, and it help you sleep too. Thinking out loud, I'm not sure what the downside is (like does Bendryl hit the Kidneys, Liver, or something like that?) Not sure.

    But as I found through self experimentation, 1 week off Clen w/ 50 mg Benadryl nightly (after 3 weeks on Clen to 80 mcg), and I was able to go back to 40 mcg, after only one week off, and get the effects at a reasonably low dose.

    By the way, I'm doing a two week break in Clen this time. With Benadryl

  11. Why don't you buy some Ketotifen from a chem site? Keto works wonders for up-regulating your receptors, and you'll sleep like a baby

  12. Quote Originally Posted by john.patterson View Post
    Why don't you buy some Ketotifen from a chem site? Keto works wonders for up-regulating your receptors, and you'll sleep like a baby
    They actually believe benadryl upregulates beta receptors.
    The difference between who you are and who you want to be is what you do.

  13. 5 year second breath of life for this thread! LOL

  14. Heads up play with the article tho, didnt know testosterone and DHT played a role in upregulating receptors
    The difference between who you are and who you want to be is what you do.

  15. Quote Originally Posted by rochabp View Post
    Heads up play with the article tho, didnt know testosterone and DHT played a role in upregulating receptors
    Reboot with test/DHT/dhea post eca/clen cycle? Whaaat? Sounds like my log

  16. Quote Originally Posted by rochabp View Post
    Heads up play with the article tho, didnt know testosterone and DHT played a role in upregulating receptors
    i dont know about beta receptors but ive seen a study that found test upregulates adrogen receptors?? and proviron also does this

  17. Quote Originally Posted by rochabp View Post
    Heads up play with the article tho, didnt know testosterone and DHT played a role in upregulating receptors
    Yup, DHEA as cited in the studies increases beta-3-densities, testosterone upregulates all of them , especially in adipose/BFT/BAT - and DHT preserves beta receptors or at least prevents them from being downregulated by some biochemical interferences. Of all of these, it's most likely that testosterone plays the biggest role , seeing as it has a potent lipolytic effect; superior to all three...but DHT can help nervous system strength too. You've all seen the DHT role in CNS / Brain article right?

  18. Quote Originally Posted by baitslinger View Post
    Why Benadryl you ask? Well, like everything else around here, you give it a try and see if it works. Benadryl is cheap as nuts, and it help you sleep too. Thinking out loud, I'm not sure what the downside is (like does Bendryl hit the Kidneys, Liver, or something like that?) Not sure.

    But as I found through self experimentation, 1 week off Clen w/ 50 mg Benadryl nightly (after 3 weeks on Clen to 80 mcg), and I was able to go back to 40 mcg, after only one week off, and get the effects at a reasonably low dose.

    By the way, I'm doing a two week break in Clen this time. With Benadryl
    Benadryl isn't really the best agent for doing this, I would use ketotifen...also , benadryl isn't purely an antihistamine, it is also a serotonin reuptake inhibitor (mild) and anti-muscarinic agent..the SRI/antimuscarinic properties are the ones that you should be worried about. Antihistamines themselves aren't that bad, if they don't cause you that much lethargy.

    Also, if you are going to Zambia..ditch the benadryl, apparently it's illegal there.

    http://en.wikipedia.org/wiki/Diphenh...nism_of_action
    http://emedicine.medscape.com/article/1010513-overview
    http://www.ncbi.nlm.nih.gov/pubmed/10511010
  

  
 

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