Not sure how high I would go with this stuff. I can't give you any science behind why 100e/800caff, etc, is the "upper limit"...at least right now (too busy). I know beyond 600 or 800mg of caffeine you start getting detrimental effects, like jacking up cortisol (I think this is right, its been a long time since I've researched it).
Personally, I use E/C only and I do half doses for appetite suppression only. I also find that if I ramp up my dosing I don't desensitize to the effects that fast. For me, appetite is the ENTIRE battle...if I can keep myself from eating, I don't have an issue burning off the fat.
I don't know which length of cycle would be better for you. Try 2 weeks straight, and if you start getting desensitized to the effects and want to cycle off, go off it for a week (2 off might be overkill). Or, alternately, do 5 on 2 off...plan the 2 "off" days around your cheat days/refeeds.
If you are starting to get desensitized, try taking benadryl at night for a week...again, its "bro-telligence", but apparently it works to stimulate Beta receptor repopulation. This idea stems from published studies on ketotifen, an antihistamine, having that affect in lung tissue (repopulating beta2 receptors for asthma users who chronically use albuterol inhalers). The MOA of ketotifen in this regard seems to be completely dependent on it's blocking the histamine receptor...BUT...ketotifen and benadryl (diphenhydramine) are different substances, and might work differently on the histamine receptor...different binding properties, different effects, etc...look at how close testosterone and methyl-1-testosterone are chemically and you'll see what I mean. In addition, I haven't seen any research showing that anti-Hs repopulate B1/B3 receptors in the rest of the body...which is what we want for fat loss, not just B2. So take this bit of advice with a grain of salt.
