Anabolic Pump FAQ

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  1. Quote Originally Posted by ono View Post
    hmm sounds like an awesome product. Just a bit concerned about the possible mental confusion it can cause if you don't stick to the recommended dosage and timings. What causes this? It's sounds like a fun side effect to have
    This is caused by your blood sugar levels dropping too low aka hypoglycemia. It is not a fun side effect at all, actually lol


  2. Quote Originally Posted by hawks31 View Post
    just a few things i want to double check before i buy this product. ive researchde it a bunch but sometimes i need direct answers from people. so basically any kind of cutting diet without carbs wont work with AP? and will AP work well with Leviathan Reloaded?
    You need carbohydrates with Anabolic Pump in order for it to work.

    AP would work with Leviathan Reloaded but make sure that you take them at the same time.
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  3. alright great Dex. and thanks for the that huge list of foods that would be alright for me to eat while on these 2 supps. but im a little curious as to why it's best to take the AP and the LR at the same times during the day.?

  4. Quote Originally Posted by dexterium View Post
    This is caused by your blood sugar levels dropping too low aka hypoglycemia. It is not a fun side effect at all, actually lol
    Haha i realised it's probably that. And yeah it's happened to me quite a few times before. It's horrible.

  5. What if I'm injured and can't lift for a week or 2? Should I continue AP?
    "I would be proud to sport that body on the beach, or for a hot date." -Dsade commenting on my pics
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  6. Can AP be takin while on PCT? I just finished a 4 week cycle of Methyl1D and now am taking Formadrol and Psarm for a PCT.
    I have a bottle of AP but should i wait until after PCT to start on it?
    I posted this in the PCT section a few days ago and got no responce,Hope i have better luck here. Thanks

    BTW, I plan on bulking at least 2 more months before cutting if that makes a difference.

  7. I think AP is a great supplement in an environment attempting to reboot one's HPTA. Not only due to its GLUT4 translocation, but also its anti-lipogenic and anti-cholesterolemic functions.

  8. Does it work well with a stack of RPM/Drive or should I wait to dose AP on its own?

  9. 11th day, not noticing anything. I've tried waiting different times, anywhere from 10-75 minutes. I've tried various amounts of complex carbs, anywhere from 35-70 grams, still nothing.

    Anything else I can do to hopefully feel the effects of this supplement?

  10. Quote Originally Posted by ono View Post
    Aha it's probably just hypoglacemia or however you spell it. That shizzle is no fun. Suppose it will be ok if i carb up when am on it....which is what i'll be doing
    You clarified your own confusion just now! Bravo.
    Freedom means nothing here.

  11. Quote Originally Posted by AM07 View Post
    11th day, not noticing anything. I've tried waiting different times, anywhere from 10-75 minutes. I've tried various amounts of complex carbs, anywhere from 35-70 grams, still nothing.

    Anything else I can do to hopefully feel the effects of this supplement?
    Have you tried any simple carbs?

  12. Quote Originally Posted by dexterium View Post
    Have you tried any simple carbs?
    Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.

  13. Quote Originally Posted by AM07 View Post
    Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.
    Even if the supplement negates any negatives associated with said simple carb? You will avoid insulin spikes, insulin resistance and weight gain that accompany them when precipitated by AP.

    I am a no sugars advocate myself ... well, I was before trying them with AP. FWIW
    Recent log:http://anabolicminds.com/forum/supplement-reviews-logs/213350-lean-efx-refined.html

  14. I picked up a couple bottles each of P-Slin and AP... DAMN! Amazing stuff! I had a really nice run with it before and wasn't afraid to abide by and trust the instructions that say : (P-Slin) "Use 60-100 grams of carbs" & (AP) "Use atleast 40 grams of complex carbs"... whatever... outstanding results manifested themselves from the first dose of each! No exaggeration!
    Freedom means nothing here.

  15. Quote Originally Posted by AM07 View Post
    Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.
    It does not require simple carbohydrates, but Dex was merely suggesting you may respond better with a mixture; this could be due to your insulin sensitivity predisposition.

  16. Before I spend almost £40 on this product will someone please explain how Phellodendron the first ingredient, works in this formula .I have searched Google and despite the claim that only USP had heard of this plant/herb ,lots of information is available through Google, quote from one-Phellodendron has been used to treat gastric ulcers, bacterial infections, fungal infections, and diabetes. It has also been used for immunosuppression and as a topical anti-inflammatory agent.

    I have no wish to knock this product as anecdotal feedback seems to be good, but if we are trying to create an anabolic window throughout the day , why not eat every 2/3 hours slow release carbs along with good quality protein.This will create an insulin rise ,and shuttle gradually nutrients into the bloodstream , but not a spike as in after training when its wanted.

    For me personally supplement companies have to do a lot more hard work and research to convince me to buy their product. So many supplements contain herbs which have been used in folklore medicine for years and for something not related to bodybuilding. As soon as it gets into the bodybuilding arena , for some reason its the icing on the cake to getting the "physique of your dreams!"

    So back to where I came in , can someone come up with information that will convince me to buy this product .I am not taken in by advertising claims .

  17. Quote Originally Posted by Mulletsoldier View Post
    It does not require simple carbohydrates, but Dex was merely suggesting you may respond better with a mixture; this could be due to your insulin sensitivity predisposition.
    But the thing is, with my diet, there is nothing that includes simple carbohydrates. I don't even consume a PWO shake; I just come home and typically eat a full meal containing complex carbohydrates and lean meat.

    So should I take an AP right after my workout, then try having a PWO shake consisting of 50 grams dextrose with 35 grams whey 20 minutes later?

    I don't understand how insulin sensitivity (specifically mine, which I doubt could be figured out just by the feel of things after I eat something) could have anything to do with this if I've tried eating at various times after taking the AP. So is it better if one has a higher insulin sensitivity (better for overall health) with this product than a lower sensitivity? Do the non-responders of this product tend to have a high insulin sensitivity?

  18. If you want to increase your own insulin sensitivity see what L.REA has to say about doing just that in his book "Building the perfect beast -naturally "


    Before spending money on a product which may or may not work .After youve read what he has to say on insulin, then decide what you want to do

  19. I believe the non-responders may have a higher resistance yes. AP often requires time to increase your sensitivity to insulin before it's full effects are realized. The increased glut4 creates an environment where less insulin is required thus less insulin is released. Over time the decreased levels increase sensitivity. For overall health this is a very good thing as even a cursory exposition to the effect of insulin will reveal it's intrinsically toxic nature.
    Recent log:http://anabolicminds.com/forum/supplement-reviews-logs/213350-lean-efx-refined.html

  20. So do you think I may not be responding because my insulin sensitivity is high or low?

  21. Quote Originally Posted by AM07 View Post
    So do you think I may not be responding because my insulin sensitivity is high or low?
    I can only speculate, but you may have some resistance or "low sensitivity". I would suggest continuing using it with your existing diet and see if you start to notice some effects by the end of the bottle. Even if you are not "feeling" anything, the process I described above regarding the glut-4 translocation and reduced insulin release should indeed still be taking place if dosing as prescribed and that is reason enough for me to continue taking it.

    Really, the overall health benefits of AP make any "pump", accelerated muscle gain or fatloss effects take second stage in my book.
    Recent log:http://anabolicminds.com/forum/supplement-reviews-logs/213350-lean-efx-refined.html

  22. Quote Originally Posted by corsaking View Post
    Before I spend almost £40 on this product will someone please explain how Phellodendron the first ingredient, works in this formula .I have searched Google and despite the claim that only USP had heard of this plant/herb ,lots of information is available through Google, quote from one-Phellodendron has been used to treat gastric ulcers, bacterial infections, fungal infections, and diabetes. It has also been used for immunosuppression and as a topical anti-inflammatory agent.

    I have no wish to knock this product as anecdotal feedback seems to be good, but if we are trying to create an anabolic window throughout the day , why not eat every 2/3 hours slow release carbs along with good quality protein.This will create an insulin rise ,and shuttle gradually nutrients into the bloodstream , but not a spike as in after training when its wanted.

    For me personally supplement companies have to do a lot more hard work and research to convince me to buy their product. So many supplements contain herbs which have been used in folklore medicine for years and for something not related to bodybuilding. As soon as it gets into the bodybuilding arena , for some reason its the icing on the cake to getting the "physique of your dreams!"

    So back to where I came in , can someone come up with information that will convince me to buy this product .I am not taken in by advertising claims .
    Phellodendron has been shown to mitigate AMPk. AMPk is immediately involved in the glycogen uptake pathway via induction of GLUT4; especially in terms of contractile tissue. GLUT4 mRNA expression and translocation can be adversely affected by the downregulation of AMPk and other kinases.

    Evidence:

    Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

    Yun S. Lee1

    Berberine has been shown to have antidiabetic properties, although its mode of action is not known. Here, we have investigated the metabolic effects of berberine in two animal models of insulin resistance and in insulin-responsive cell lines. Berberine reduced body weight and caused a significant improvement in glucose tolerance without altering food intake in db/db mice. Similarly, berberine reduced body weight and plasma triglycerides and improved insulin action in high-fat–fed Wistar rats. Berberine downregulated the expression of genes involved in lipogenesis and upregulated those involved in energy expenditure in adipose tissue and muscle. Berberine treatment resulted in increased AMP-activated protein kinase (AMPK) activity in 3T3-L1 adipocytes and L6 myotubes, increased GLUT4 translocation in L6 cells in a phosphatidylinositol 3' kinase–independent manner, and reduced lipid accumulation in 3T3-L1 adipocytes. These findings suggest that berberine displays beneficial effects in the treatment of diabetes and obesity at least in part via stimulation of AMPK activity.
    As stated, this study explains Berberine's ability to regulate energy expenditure as a whole - rather than simply glucose metabolism - in both myocytes and adipocytes. Further, it inhibited both differentiation and hypertrophy in accumulated lipids, most likely regulating the PPAR family. In terms of the AP-specific glucose effect, it lead to increased levels of GLUT4 in myocytes specifically.

    Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

    Zhe Cheng, Tao Pang, Min Gu, An-Hui Gao, Chuan-Ming Xie, Jing-Ya Li, Fa-Jun Nan and Jia Li

    National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, P. R. China


    Received 17 May 2006; revised 13 September 2006; accepted 13 September 2006. Available online 20 September 2006.

    Abstract

    Berberine is a plant alkaloid used in traditional Chinese medicine and has been reported to have antihyperglycemic activity in NIDDM patients. However, the molecular basis for this action is yet to be elucidated. Here we investigate the effects and signaling pathways of berberine on L6 rat skeletal muscles. Our study demonstrates that berberine stimulates glucose uptake in a time- and dose-dependent manner. Intriguingly, berberine-stimulated glucose uptake does not vary as insulin concentration increases, and could not be blocked by the PI 3-kinase inhibitor wortmannin. Berberine only weakly stimulates the phosphorylation of Akt/PKB, a key molecule in the insulin signaling pathway, but strongly promotes the phosphorylation of AMPK and p38 MAPK. The effects of berberine are not a result of pro-oxidant action, but a consequence of an increased cellular AMP:ATP ratio. Moreover, berberine-stimulated glucose uptake is inhibited by the AMPK inhibitor Compound C and the p38 MAPK inhibitor SB202190. Inhibition of AMPK reduces p38 MAPK phosphorylation, suggesting that AMPK lies upstream of p38 MAPK. These results suggest that berberine circumvents insulin signaling pathways and stimulates glucose uptake through the AMP-AMPK-p38 MAPK pathway, which may account for the antihyperglycemic effects of this drug.
    As stated above, AMPk regulates glucose metabolism through insulin-reactive, though not necessarily insulin-dependent, pathways. It has a weak affinity for Akt/PKB which are IR-dependent compounds, whereas both studies show a direct induction of AMPk/p38 MAPK, which are more or less GLUT4 specific kinases. This all leads to lower serum levels of insulin via increased glycogen storage while circumventing insulin's action.

    Lagerstroemia (extracted for both Corosolic and Tannic Acid) works in a corollary manner - creating positive energy turnover ratios between adipocytes and myocytes.

  23. Quote Originally Posted by AM07 View Post
    So do you think I may not be responding because my insulin sensitivity is high or low?
    It could very well be either. If you are sensitive to the action of insulin already, than the insulin-reactive pathways AP is mitigating will not see immediate benefit; similarly, if you have been insensitive to the action of insulin, AP may take some time to affect the above mentioned kinases.

    How long have you been using the product?

  24. Quote Originally Posted by bpmartyr View Post
    I believe the non-responders may have a higher resistance yes. AP often requires time to increase your sensitivity to insulin before it's full effects are realized. The increased glut4 creates an environment where less insulin is required thus less insulin is released. Over time the decreased levels increase sensitivity. For overall health this is a very good thing as even a cursory exposition to the effect of insulin will reveal it's intrinsically toxic nature.
    I saw results immediately... I pretty much already had the carbohydrate content already setup in a configuration that's optimal for AP and P-Slin. Now, all I had to do was dose it 15 minutes before hand. I'm amazed.
    Freedom means nothing here.
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