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There is our official write-up w/full citations if you choose to investigate further.
In a basic summary, Cissus blocks the reception of certain pro-inflammatory Cytokines (proteinacous compounds which are involved in a number of immune responses),as well as selective glucocorticoids which degrade bone, muscle, and connective tissue (cortisol is the most famously lamented one). As opposed to taking a reactive approach, Cissus takes a proactive role in simultaneously preventing and healing such degradation.