I find that results with Prime get better with time. It usually takes about two weeks to really hit for me, so I would say yes there does seem to be a saturation point. Don't take any time off, just continue dosing and make sure not to miss days. Write yourself notes, set reminders on your cell phone, whatever you have to do. As for your schedule, that looks pretty good. I wouldn't do two before bed, as I think all but the preworkout dose should be taken with meals (particularly containing healthy fats). Even dosing throughout the day is probably the most important factor.