[warriorway]

I'm going to whip up a transdermal forskolin. I am also thinking of adding some yohimbine, I've read that oral vs. trans is equally effective but I can make tons of transdermals and it's easier than capping. I also want to add some kind of antioxidant to the mix, perhaps cat's claw.

Anyone else have any suggestions?

Here are links to a couple articles:

Natural Acne Treatment
Coleus oil was found to more effectively inhibit the growth of skin pathogens including Propionibacterium acnes (associated with acne) 7 , Staphylococcus aureus (a bacterial strain found in infected wounds and skin eruptions including acne) 8 , Staphylococcus epidermis a bacterial strain occurring in a variety of opportunistic bacterial skin infections and in acne.


Rosacea • topical forskolin: possible rub on tan
Another potential way to increase the amount of melanin in the skin is gaining some publicity from a Sep. 21 article in Nature. Whereas melanotan (Clinuvel, epitan) uses a synthetic melanocyte stimulating hormone, forskolin stimulates the production of melanocyte in fair skinned individuals by raising a chemical known as cyclic AMP (cAMP)

[warriorway]

Does anybody have any of the stronger extracts of forskolin? Anywhere from 40-95%. I would be interested in trading for some of my homebrew TDS(transdermal delivery system).

Otherwise the 20% forskolin we can get from board sponsors will be fine. I have read that forskolin may work synergistically with all the other compounds in coleus forskolli.

[pmiller383]

Well I am pretty interested to see your results here, I hope you find a stronger extract. The only thing I have seen that was extremely pure was USP's bolic, but that was a limited run supp.

[warriorway]

CustomNW told me he was working on getting the 95% stuff again. Of course for the acne fighting it's actually the essential oils in the herb and not the forskolin that is credited. But yeah, if I had 40-50% forskolin then that would be better.

[warriorway]

Looks like Coleus oil takes care of some Staph too.

[jmh80]

Sounds very interesting. Keep us updated.
I'm interested in your results.

I just have no idea what carrier you'd put this stuff in. Might want to ask the Avant folks.

[warriorway]

Forskolin is soluble in dmso and ethanol, I hope Isopropyl alcohol will work because ethanol does irritate the skin.

I have all the supplies to make a hydro alcoholic carrier, kind of like t-gel. I'll just have to play around with the formula and I think it will work.

[jmh80]

DMSO is a no-no for me. I used it when I ran 1-test/4-ad a few years ago - really irritated my skin for a long time.

Skulpt I can tolerate for 4 days per week - then I have to use something else.

[EasyEJL]

i've been pondering trying this too, was waiting till I could find over 90% forslean without having to buy a kilo from sabinsa

[warriorway]

Yeah I don't want to use dmso either, hopeful isopropyl alcohol will work. I've seen msm used in transdermals before, I don't know how harsh that would be on skin though.

Methylsulfonylmethane (MSM) -- also known as methyl sulfone or dimethylsulfone (DMSO2) -- is an odorless breakdown product of dimethyl sulfoxide (DMSO)

[warriorway]

I found 2 similar products on the net where yohimbine was the main ingredient. One was Patrick Arnolds, it was Water, isopropyl alcohol, dmso based. The other one I found only had water and carbomer.

I will use forskolin and greet tea extract in a 2:1 ratio. I am using green tea for the antioxidant EGCG, and a little caffeine kick.

For my TDS I will try something that should be easy on the skin. I guess the formula depends on how well the alcohol and terpenes can dissolve the forskolin. I don't want to use too much alcohol so I'm going to try starting at 20%

Water 50%
isopropyl alcohol 20%
emulsifying wax 10%
extra virgin coconut oil 5% (for lauric acid and skin penetrating enhancer)
extra virgin olive oil 5% (for oleic acid, spe and vit E)
sweet almond oil 5% (for vit B1,B2,B3, B6 and B9)
d-limonene 2.5% (for a natural terpene, vit c and spe)
eucalyptus oil 2.5% (for a natural terpene, antibacterial, and spe)

edit
That formula didn't work and the eucalyptus stinks.

[bound]

Subbed, cause I've got that wonderfully burnable Irish skin.

[warriorway]

My second batch I am more happy with, but not quite 100% It seemed to work well but it's dark brown. Maybe I should back off on the ammount of forskolin I put in it. In 4 oz of carrier I put in 7 grams forskolin and 3.5g green tea. I rubbed 1/2ml on the back side of my L forearm. It seemed to darken the skin for 5 minutes or so but now there's no significant difference between my other arm.

It has a nice sweet eastern spice smell, there is absolutely no citrus scent from the limonene. In the 1t 4 ad trans I'm using the lemon scent just kills me.
There is no oily residue left on the skin, maybe I can increase the ammount of oil in it and the d-limonene.
It is a little thin for my liking, I like a thicker smoother product.

The formula I used was closer to my tried and true recipe, I didn't want to play around. My first batch with all the water didn't hold too well, I think it seperated from the water and clumped together.


I think for my next experiment I will cut out the water and see what happens.

[warriorway]

I have a pretty good formula I think anyone could make. If not for the isopropyl alcohol everything in it is natural. The stuff goes on good, it's thin but doesn't run all over the place. It dries fast, doesn't feel greasy and makes you look tan!

I got it pretty potent for my sample 2oz batch. I put in 5 grams forskolin and 2.5 grams green tea extract. That equates to 125mg per ml.

Here's the ratio's

isopropyl alcohol 40%
emulsifying wax 10%
extra virgin coconut oil 20% (for lauric acid and skin penetrating enhancer)
extra virgin olive oil 10% (for oleic acid, spe and vit E)
sweet almond oil 10% (for vit B1,B2,B3, B6 and B9)
d-limonene 10% (for a natural terpene, vit c and spe)

1st step
In a glass jar measure out the alcohol and d-limonene. Then add the forskolin and green tea. Warm it in the microwave for 20 sec, shake until blended.

2nd step
In a seperate glass jar measure out the oil's and emulsifying wax. Warm it in the microwave in 30 second increments until fully melted.

3rd step
Re warm the forskolin for 10 sec in the microwave and slowly stir in the oil mix. Stir for 1 minute to get a good emulsion.

The next part I found works best for getting it thicker, otherwise if I just bottle it, it stays very runny. I put the jar in the freezer uncovered for 10-15 minutes until it turns into a thick paste. Then I take it out and let it warm up some it will become thinner. Use a funnel and pour it into your lotion bottle. Voila your done!

Emulsifying wax is very cheap I got mine from snowdriftfarm.com The d-limonene I got at greenterpene. com
Everything else you can get at the grocery store and from board sponsors.

Edit-
The freezer trick didn't work too well at these ratio's. It did work on my previous batch when I had half the alcohol and much less forkolin. The color was also a medium brown instead of dark brown. It felt too greasy though, like I just got a massage from this chick who likes to use alot of lube.

[EasyEJL]

hmm the question is how well does it work with sun added

[warriorway]

It's supposed to work pretty well for people. They did not burn as easy and got a deeper tan than normal.