Thats a lot of questions you've got there. I'm looking to run a transdermal 1test/4ad cycle as well in the near future so I'm trying to work this stuff out myself. First, how many grams do you have of each (1test/4ad)? How long do you want to run the cycle? And what are your goals for the cycle? I'll try to help you the best I can with the information you gave me.
You should use 12g of powder for each carrier as this is just about the saturation point. I would personally do different carriers for the 4ad and the 1test so you can play with the doses. Here is an example of what I am going to do: 8 week cycle, 300mg 1test/600mg 4ad per day (keep in mind this is a pretty large dose). This would mean I need 24g of 4ad and 12g of 1test. That would mean I need 3 transdermal carriers, since each one will be holding 12g of powder.
Mixing the doses individually would be a total pain in the ass so I would say pass on doing it that way. In order to figure out the conversion you must know that each bottle of penetrate is 8oz's or ~240ml. Since you are putting in 12g of powder that would be 12000mg/240ml, or ~100mg per 2-2.5 ml. I would use an oral syringe to measure out doses because often times the squirt bottles will get clogged with powder.
The way to mix it is to get a pot and boil water. Then get a glass jar and pour the contents of the penetrate into the jar. Put the jar in the boiling water until the penetrate is heated. Slowly pour the powder into the jar while mixing (doing it slowly should ensure that all the contents get mixed in). If you are having a problem getting the contents fully mixed in you can add a marble to the jar to help crush up the powder. Once you get the 12g in and mixed you can put a lid on the jar and shake it up. If its not all mixed in, put it back in the hot water for a bit and repeat this step until the powder is thoroughly mixed in.
If your goal for the cycle is to gain lean or cut, then a good ratio is 2 parts 1test/1 part 4ad. You can also do a 1/1 ratio. If you don't mind bloat, the best gains will be at 1 part 1test/2 parts 4ad and this should surely take care of the lethargy/libido from the 1test. If you choose the latter option, I would say probably start out at 200mg 1test/400mg 4ad. You should apply your transdermal twice daily, say once in the morning and again at night.