Gyno Gel Homebrew: Is it possible?

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  1. I would guess it has to do with it being metabolized differently in the skin compared to taking it orally. I don't know if it would help with Dbol, but it might. The downside would be a large decrease in bioavailability, since transdermally you would only get maybe 20%, if not less (not sure on the exact %, just know it would be less)

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  2. BROMO


    I was doing a combination of inj fina w/test prop from Dazed's kit (100 mg prop, 75 mg tren eod) and could have sworn I was getting gyno (nipple tenderness, itching, etc.). This was despite the fact that I was taking arimidex at .5 mg ed and nolvadex 80mg ed. But I was also taking some trazadone (100 mg ed) and recalled reading that both trazadone and fina elevate prolactin. So, I stopped taking the trazadone and started taking 2.5 mg bromo twice a day and the symptoms went away within several days.

  3. 3-beta would be much better suited for home brew anactrim gel since it attatches itself to the estrogen receptor. Throw in some yohimbine and you would be in good shape. The only problem would be you would not want to use alcohol if you were applying it to your nips since it would cause great irritation.

    If someone could come up to a brew similar to Yomiburn, maybe with some DMSO and some other absorption ingredients and take that along with an anti-e I'm sure it would be great for relieving gyno.

  4. Originally posted by pogue
    3-beta would be much better suited for home brew anactrim gel since it attatches itself to the estrogen receptor. Throw in some yohimbine and you would be in good shape. The only problem would be you would not want to use alcohol if you were applying it to your nips since it would cause great irritation.

    If someone could come up to a brew similar to Yomiburn, maybe with some DMSO and some other absorption ingredients and take that along with an anti-e I'm sure it would be great for relieving gyno.
    Yes, but I believe that the ER would be effectively antagonized from local DHT if simply 5aa was used....?
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  5. Originally posted by nightop


    Yes, but I believe that the ER would be effectively antagonized from local DHT if simply 5aa was used....?
    No idea. The mfg of anactrim might have some data about localized DHT, but when we start using PHs, we're on our own

  6. Originally posted by pogue


    No idea. The mfg of anactrim might have some data about localized DHT, but when we start using PHs, we're on our own
    ooops nvmd, I was confusing 3-beta with 3-alpha....

    I was referring to local conversion of 5aa to DHT (which has ER antagonistic properties).
  7. what ever happened to Viratase?


    It's supposed to be an anti-E. Did it get caught up in the ph ban?

  8. Just wanted to point out that depending on how your gyno was formed, it may not be an issue of estrogen, but rather an issue of prolactin.

    Cabergoline (I hope I spelled that right) and vitamin B6 seem to work wonders for this.

    Pyridoxine (B6) has a MW of 167, and although oral administration has worked wonders for me in the past, I'm not knowledgable enough on the subject to say whether or not a localized TD effect would be beneficial for your cause. Just something else to think about when trying to get the nips to shrink back up.

  9. Quote Originally Posted by thesinner
    Just wanted to point out that depending on how your gyno was formed, it may not be an issue of estrogen, but rather an issue of prolactin.

    Cabergoline (I hope I spelled that right) and vitamin B6 seem to work wonders for this.

    Pyridoxine (B6) has a MW of 167, and although oral administration has worked wonders for me in the past, I'm not knowledgable enough on the subject to say whether or not a localized TD effect would be beneficial for your cause. Just something else to think about when trying to get the nips to shrink back up.
    I think you are off on that line of thinking. I believe that gyno is always estrogen related. It can be exacerbated by progesterone.

    check out the thread below, posts 24,25 &26 especially:

    anti progesterone?
    Give a man a fish, feed him for a day. Teach a man to fish, feed him for life. Lao Tse 6th century BC

  10. Interesting read....so whats the winning TD formula for gyno?

  11. I did some 6-oxo in DMSO and applied it to the gyno, and I diod it befoer by simply mixing Letrozol with PEG and alcohols.

    Both worked very well and Ive got a significant reduction in size, as well as the 6-oxo seems to do very well transdermal as a systemic aromatase inhibitor as well as letro.

  12. Sry, but the only cure that I have ever witnessed is surgery.
    I would love to see a topical cure, but it doesnt seem likely

  13. Quote Originally Posted by ianm4208 View Post
    Sry, but the only cure that I have ever witnessed is surgery.
    I would love to see a topical cure, but it doesnt seem likely
    Well, since Andractim is hormonal and acts directly on the breast cells, it can and does work for some people. Probably worth a try before going straight to surgery.
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