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Old 09-04-2004, 04:11 PM   #1
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Dissolve caffeine into transdermal?

Does anyone know what chemical(s) is needed to dissolve caffeine anhydrous? I mixed 3 grams 7oxo and 5 grams of caffeine anhydrous into 125 millileters of transdermal solution and the caffeine wont dissolve. I used the following recipe:

40% isopropyl alcohol
15% isopropyl myristate
15% isopropyl palmitate
10% oleic acid
10% dmso
10% propylene glycol

Thanks for your help guys!

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Old 09-04-2004, 08:41 PM   #2
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Are you sure it is the caffeine not disolving. Trans 7-OXO (FL7) is usually a bit grainy/cloudy. Caffeine is water soluable, no? Though, you could be pushing the saturation point.
 

Last edited by b5150 : 09-04-2004 at 10:38 PM.
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Old 09-21-2004, 12:10 PM   #3
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Caffeine is hydrophilic, 7oxo lipophilic. I have no idea what carrier you should use though.

Could you dissolve both in the same dermal?
 
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