Dissolve caffeine into transdermal?

[nozzi]

Does anyone know what chemical(s) is needed to dissolve caffeine anhydrous? I mixed 3 grams 7oxo and 5 grams of caffeine anhydrous into 125 millileters of transdermal solution and the caffeine wont dissolve. I used the following recipe:

40% isopropyl alcohol
15% isopropyl myristate
15% isopropyl palmitate
10% oleic acid
10% dmso
10% propylene glycol

Thanks for your help guys!

Nozzi

 

[B5150]

Are you sure it is the caffeine not disolving. Trans 7-OXO (FL7) is usually a bit grainy/cloudy. Caffeine is water soluable, no? Though, you could be pushing the saturation point.

 

[meathead1987]

Caffeine is hydrophilic, 7oxo lipophilic. I have no idea what carrier you should use though.

Could you dissolve both in the same dermal?