Topical Tamoxifen experiment.

  1. New Member
    Autobody's Avatar
    Join Date
    Mar 2009
    Posts
    57
    Rep Power
    98
    Level
    7
    Lv. Percent
    8.03%

    Topical Tamoxifen experiment.


    following this study.

    Tamoxifen-Loaded Liposomal Topical Formulation Arrests Hair Growth in Mice.
    Bhatia A, Singh B, Amarji B, Katare OP.

    University Institute of Pharmaceutical Sciences - UGC Centre of Advanced Study Panjab University, Chandigarh, India.
    ABSTRACT Background For several decades, androgens have dominated endocrine research in the domain of hair growth control. However, it has long been known that estrogens also tend to alter hair follicle (HF) growth and cycling significantly by binding to locally expressed high-affinity estrogen receptors (ER). Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM). Objective The current work aims to investigate the effect of topically applied TAM on the hair growth of mice. Method The test formulations were applied once-a-day on the shaved back area of the mice consecutively for a period of five weeks. The effect of these formulations was studied by visual and histological examinations. Results The saline and placebo-gel formulation treated animals showed significant hair growth on the 20(th) day. The number and length of follicles were also found to be normal. In contrast, no hair growth was observed in the animals treated with TAM-gel, even after the termination of treatment. The HFs found to be arrested in telogen phase with clear signs of follicle dystrophy. Conclusion Hair growth retarding effect of TAM observed in the current studies, clearly demonstrates its ER agonistic effect on hair growth. This work also provides a distinct lead towards the possible potential of TAM liposomal-gel in the treatment of hirsutism.
    Id like to make and try a small amount of this on a tiny patch of skin with hair to see what happens. It only needs to get into the pores I believe to disable to follicles.

    any comments before I die of sitting in a vat of tamoxifen?

  2. New Member
    weeniman's Avatar
    Stats
    6'0"  280 lbs.
    Join Date
    Jul 2009
    Posts
    70
    Rep Power
    101
    Level
    7
    Lv. Percent
    66.75%

    If it works, I hope your vat has room for me.
  3. New Member
    dizdabiz's Avatar
    Stats
    4'6"  900 lbs.
    Join Date
    Nov 2008
    Posts
    84
    Rep Power
    117
    Level
    8
    Lv. Percent
    73.89%

    If it works, I hope your vat has room for me.
    That^^^ just sounds soooo wrong! lol, just kidding! Subbed mr autobody, I love experiments and want to see how this one ends up, hopefully well!
    •   
       

  4. Professional Member
    celc5's Avatar
    Stats
    5'10"  195 lbs.
    Join Date
    Mar 2007
    Age
    35
    Posts
    3,211
    Rep Power
    140365
    Level
    41
    Lv. Percent
    89.93%
    Achievements Activity ProPosting Pro

    subbed....
  5. New Member
    weeniman's Avatar
    Stats
    6'0"  280 lbs.
    Join Date
    Jul 2009
    Posts
    70
    Rep Power
    101
    Level
    7
    Lv. Percent
    66.75%

    It must have killed him....

    Wonder if his corpse is nice and smooth?

  6. Advanced Member
    bulldogz's Avatar
    Join Date
    Dec 2007
    Age
    39
    Posts
    954
    Rep Power
    562
    Level
    23
    Lv. Percent
    84.44%

    interesting....subbed!
  7. New Member
    DogSlime's Avatar
    Join Date
    Jan 2008
    Posts
    10
    Rep Power
    90
    Level
    2
    Lv. Percent
    78.5%

    updates?
  8. Advanced Member
    james122's Avatar
    Stats
    6'4"  230 lbs.
    Join Date
    Feb 2010
    Posts
    570
    Rep Power
    1739
    Level
    19
    Lv. Percent
    41.69%

    Quote Originally Posted by weeniman View Post
    It must have killed him....

    Wonder if his corpse is nice and smooth?

    lol
    for while bodily training is of some value, godliness is of value in every way, as it holds promise for the present life and also for the life to come 1 Tim 4:8
  9. New Member
    novicebb's Avatar
    Stats
    5'11"  289 lbs.
    Join Date
    Feb 2010
    Posts
    22
    Rep Power
    70
    Level
    4
    Lv. Percent
    41.15%

    I remember reading about this study in an Muscular Development mag and emailed Dr. Colker about the possible positive applications of Topical Tamoxifen. At the time use the name Podthebod. Made fun of my name in the article and called me PodtheBoob. Never forget that.

    Definitely would love to see the effects of Topical Raloxifene on Male breast tissue sites and if there are any effects.
  10. Board Moderator
    Never enough
    EasyEJL's Avatar
    Stats
    5'10"  205 lbs.
    Join Date
    Jun 2007
    Age
    47
    Posts
    31,888
    Rep Power
    852764
    Level
    95
    Lv. Percent
    49.84%
    Achievements Activity VeteranActivity RoyaltyActivity ProActivity AuthorityPosting Pro

    I wonder what the tamox concentration was for the gel?
  

  
 

Similar Forum Threads

  1. Is there a difference between Tamoxifen and Tamoxifen Citrate?
    By compcentral in forum Post Cycle Therapy
    Replies: 1
    Last Post: 01-09-2010, 03:05 PM
  2. tamoxifen citrate-tamoxifen question
    By Brian5225 in forum Post Cycle Therapy
    Replies: 21
    Last Post: 01-11-2008, 10:52 PM
  3. Topical tamoxifen to prevent excessive scar tissue
    By YellowJacket in forum Anabolics
    Replies: 3
    Last Post: 02-12-2003, 08:07 PM
  4. Topical tamoxifen to prevent excessive scar tissue
    By YellowJacket in forum Anabolics
    Replies: 0
    Last Post: 02-03-2003, 10:27 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in